STRINGSTRING
Hmgcs2 Hmgcs2 Stat6 Stat6 Ghr Ghr LOC101835654 LOC101835654 Cacybp Cacybp Igfbp5 Igfbp5 Ptk2 Ptk2 LOC101842510 LOC101842510 Myc Myc Pik3r1 Pik3r1 Jak2 Jak2 Stat3 Stat3 Irf1 Irf1 Jak1 Jak1 ENSMAUP00000008932 ENSMAUP00000008932 Jak3 Jak3 F7 F7 Cps1 Cps1 Socs2 Socs2 LOC110339561 LOC110339561 ENSMAUP00000012061 ENSMAUP00000012061 Ghsr Ghsr Akt1 Akt1 Ass1 Ass1 Slc34a1 Slc34a1 Pxn Pxn Pnpt1 Pnpt1 Phex Phex Tyk2 Tyk2 Ugt2b1 Ugt2b1 Srd5a1 Srd5a1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Hmgcs23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
Stat6Signal transducer and activator of transcription. (746 aa)
GhrGrowth hormone receptor. (593 aa)
LOC101835654Signal transducer and activator of transcription. (228 aa)
CacybpCalcyclin-binding protein. (222 aa)
Igfbp5Insulin-like growth factor-binding protein 5. (271 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (667 aa)
LOC101842510Signal transducer and activator of transcription 5A. (228 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Jak2Tyrosine-protein kinase. (1132 aa)
Stat3Signal transducer and activator of transcription. (758 aa)
Irf1Interferon regulatory factor. (132 aa)
Jak1Tyrosine-protein kinase. (1161 aa)
ENSMAUP00000008932annotation not available (196 aa)
Jak3Tyrosine-protein kinase. (1080 aa)
F7Coagulation factor VII. (446 aa)
Cps1Carbamoyl-phosphate synthase [ammonia], mitochondrial. (1500 aa)
Socs2Suppressor of cytokine signaling 2. (198 aa)
LOC110339561Signal transducer and activator of transcription 5B-like. (125 aa)
ENSMAUP00000012061annotation not available (121 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Ass1Argininosuccinate synthase. (412 aa)
Slc34a1Sodium-dependent phosphate transport protein 2A. (320 aa)
PxnPaxillin; Belongs to the paxillin family. (589 aa)
Pnpt1Polyribonucleotide nucleotidyltransferase 1, mitochondrial. (790 aa)
PhexPhosphate-regulating neutral endopeptidase. (749 aa)
Tyk2Tyrosine-protein kinase. (1190 aa)
Ugt2b1UDP-glucuronosyltransferase 2B1; Belongs to the UDP-glycosyltransferase family. (530 aa)
Srd5a13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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