STRINGSTRING
Pde4a Pde4a Syt11 Syt11 Fbxl20 Fbxl20 Cplx1 Cplx1 Pfn1 Pfn1 ENSMAUP00000013077 ENSMAUP00000013077 Chrm1 Chrm1 Gabbr1 Gabbr1 Cacng3 Cacng3 Grasp Grasp Ghsr Ghsr Stx3 Stx3 Ppp3ca Ppp3ca Adcy1 Adcy1 Nptn Nptn Picalm Picalm Apba2 Apba2 Sh3gl1 Sh3gl1 Anks1b Anks1b Dgki Dgki Synpo Synpo Rnf216 Rnf216 Synj1 Synj1 Gipc1 Gipc1 Slc6a7 Slc6a7 Apba1 Apba1 Ntng1 Ntng1 Epn1 Epn1 Dcc Dcc ENSMAUP00000007344 ENSMAUP00000007344 ENSMAUP00000007276 ENSMAUP00000007276 Stat3 Stat3 Actb Actb Cacna1b Cacna1b L1cam L1cam Lrfn2 Lrfn2 Dgkz Dgkz Lrrc4c Lrrc4c Fyn Fyn ENSMAUP00000005330 ENSMAUP00000005330 Syn1 Syn1 Fmr1 Fmr1 Myo6 Myo6 Iqsec1 Iqsec1 Snap91 Snap91 Nefl Nefl Capzb Capzb Cdc42 Cdc42 Epha4 Epha4 Grm1 Grm1 Cadm1 Cadm1 Nrxn3-2 Nrxn3-2 Ptprs Ptprs Plg Plg Adora2b Adora2b Actg1 Actg1 Plcg1 Plcg1 Myo5a Myo5a Apbb1 Apbb1 Efnb2 Efnb2 Grm5 Grm5 Ctnnb1 Ctnnb1 Myo5b Myo5b Itgb1 Itgb1 Dtnbp1 Dtnbp1 Tnr Tnr LOC101824858 LOC101824858 Ptprd Ptprd Epha7 Epha7 Cdh11 Cdh11 Cacng2 Cacng2 Gsk3b Gsk3b Gria2 Gria2 Plat Plat Syp Syp Prkcz Prkcz Cdk5 Cdk5 Wnt7a Wnt7a Pfn2 Pfn2 Itpr1 Itpr1 Iqsec2 Iqsec2 Pcdh8 Pcdh8 Cask Cask Rab11a Rab11a Lrrtm2 Lrrtm2 Baiap2 Baiap2 Shank1 Shank1 Camk2a Camk2a Ctnnd1 Ctnnd1 Ntng2 Ntng2 Akap12 Akap12 Dvl1 Dvl1 Prkci Prkci Ghrl Ghrl Ncam1 Ncam1 Slc30a1 Slc30a1 Stxbp5 Stxbp5 Csnk2b Csnk2b Mpp2 Mpp2 Lrrc4 Lrrc4 Abr Abr Cacng8 Cacng8 Ptpra Ptpra Bcr Bcr Sh3gl2 Sh3gl2 Ppp3r1 Ppp3r1 P2rx3 P2rx3 Adcy8 Adcy8 Gsg1l Gsg1l
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pde4aPhosphodiesterase. (843 aa)
Syt11Synaptotagmin-11 isoform X1. (124 aa)
Fbxl20F-box/LRR-repeat protein 20 isoform X2. (436 aa)
Cplx1Complexin-1. (134 aa)
Pfn1Profilin; Belongs to the profilin family. (140 aa)
ENSMAUP00000013077annotation not available (450 aa)
Chrm1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
Gabbr1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (979 aa)
Cacng3Voltage-dependent calcium channel gamma-3 subunit isoform X1. (315 aa)
GraspGeneral receptor for phosphoinositides 1-associated scaffold protein. (396 aa)
GhsrGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Stx3Syntaxin-3 isoform X1; Belongs to the syntaxin family. (289 aa)
Ppp3caSerine/threonine-protein phosphatase. (521 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1118 aa)
NptnNeuroplastin isoform X1. (397 aa)
PicalmPhosphatidylinositol-binding clathrin assembly protein. (531 aa)
Apba2Amyloid beta A4 precursor protein-binding family A member 2 isoform X1. (750 aa)
Sh3gl1endophilin-A2. (368 aa)
Anks1bAnkyrin repeat and sterile alpha motif domain-containing protein 1B. (1234 aa)
DgkiDiacylglycerol kinase. (1052 aa)
SynpoSynaptopodin isoform X1. (929 aa)
Rnf216E3 ubiquitin-protein ligase RNF216. (842 aa)
Synj1Synaptojanin-1 isoform X9. (1308 aa)
Gipc1PDZ domain-containing protein GIPC1. (333 aa)
Slc6a7Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (644 aa)
Apba1Amyloid beta A4 precursor protein-binding family A member 1 isoform X2. (837 aa)
Ntng1netrin-G1. (480 aa)
Epn1Epsin-1 isoform X1. (576 aa)
DccNetrin receptor DCC. (1354 aa)
ENSMAUP00000007344annotation not available (180 aa)
ENSMAUP00000007276annotation not available (359 aa)
Stat3Signal transducer and activator of transcription. (758 aa)
ActbActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
Cacna1bVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2331 aa)
L1camNeural cell adhesion molecule L1 isoform X1. (1259 aa)
Lrfn2Leucine-rich repeat and fibronectin type-III domain-containing protein 2. (788 aa)
DgkzDiacylglycerol kinase. (946 aa)
Lrrc4cLeucine-rich repeat-containing protein 4C. (640 aa)
FynTyrosine-protein kinase. (537 aa)
ENSMAUP00000005330annotation not available (140 aa)
Syn1Synapsin-1 isoform X1. (706 aa)
Fmr1Synaptic functional regulator FMR1. (355 aa)
Myo6Unconventional myosin-VI isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1272 aa)
Iqsec1IQ motif and SEC7 domain-containing protein 1 isoform X5. (1099 aa)
Snap91Clathrin coat assembly protein AP180 isoform X3. (892 aa)
NeflNeurofilament light polypeptide; Belongs to the intermediate filament family. (236 aa)
CapzbF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
Cdc42Cell division control protein 42 homolog isoform X1. (191 aa)
Epha4Ephrin type-A receptor 4 isoform X1. (986 aa)
Grm1Metabotropic glutamate receptor 1. (829 aa)
Cadm1Cell adhesion molecule 1 isoform X1. (474 aa)
Nrxn3-2Neurexin 3 isoform X24. (75 aa)
PtprsReceptor-type tyrosine-protein phosphatase S. (1930 aa)
PlgPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (797 aa)
Adora2bAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
Actg1Actin gamma 1. (133 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1293 aa)
Myo5aUnconventional myosin-Va; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1810 aa)
Apbb1Amyloid beta A4 precursor protein-binding family B member 1 isoform X1. (710 aa)
Efnb2ephrin-B2; Belongs to the ephrin family. (336 aa)
Grm5Metabotropic glutamate receptor 5 isoform X1. (1203 aa)
Ctnnb1Catenin beta-1. (781 aa)
Myo5bUnconventional myosin-Vb isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1843 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (92 aa)
Dtnbp1Dysbindin isoform X2. (355 aa)
Tnrtenascin-R isoform X1. (1358 aa)
LOC101824858Synaptic functional regulator FMR1. (280 aa)
PtprdReceptor-type tyrosine-protein phosphatase delta. (1883 aa)
Epha7Ephrin type-A receptor 7 isoform X1. (834 aa)
Cdh11Cadherin-11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
Cacng2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
Gsk3bGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (429 aa)
Gria2Glutamate receptor 2 isoform X3. (883 aa)
PlatPlasminogen activator; Belongs to the peptidase S1 family. (559 aa)
SypSynaptophysin. (313 aa)
PrkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
Cdk5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (318 aa)
Pfn2Profilin; Belongs to the profilin family. (91 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
Iqsec2IQ motif and SEC7 domain-containing protein 2. (1299 aa)
Pcdh8Protocadherin-8 isoform X1. (1069 aa)
CaskPeripheral plasma membrane protein CASK isoform X4; Belongs to the MAGUK family. (913 aa)
Rab11aRas-related protein Rab-11A. (216 aa)
Lrrtm2Leucine-rich repeat transmembrane neuronal protein 2. (518 aa)
Baiap2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
Shank1SH3 and multiple ankyrin repeat domains protein 1 isoform X1. (2166 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
Ctnnd1Catenin delta-1 isoform X7. (967 aa)
Ntng2netrin-G2 isoform X1. (564 aa)
Akap12A-kinase anchor protein 12 isoform X1. (836 aa)
Dvl1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (695 aa)
PrkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
GhrlGhrelin and obestatin prepropeptide. (78 aa)
Ncam1Neural cell adhesion molecule 1 isoform X5. (851 aa)
Slc30a1LOW QUALITY PROTEIN: zinc transporter 1. (478 aa)
Stxbp5Syntaxin-binding protein 5. (1136 aa)
Csnk2bCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
Mpp2MAGUK p55 subfamily member 2 isoform X2; Belongs to the MAGUK family. (552 aa)
Lrrc4Leucine-rich repeat-containing protein 4. (651 aa)
AbrActive breakpoint cluster region-related protein. (872 aa)
Cacng8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (412 aa)
PtpraReceptor-type tyrosine-protein phosphatase alpha. (793 aa)
BcrBreakpoint cluster region protein. (1065 aa)
Sh3gl2endophilin-A1. (347 aa)
Ppp3r1Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (157 aa)
P2rx3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
Gsg1lGerm cell-specific gene 1-like protein isoform X1. (324 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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