STRINGSTRING
Slf1 Slf1 Pias4 Pias4 Otub2 Otub2 Arid2 Arid2 Ppp4r2 Ppp4r2 Spire2 Spire2 Timeless Timeless Rad51ap1 Rad51ap1 Ppp4c Ppp4c Fmn2 Fmn2 Parp3 Parp3 Setd2 Setd2 Morf4l1 Morf4l1 Ruvbl2 Ruvbl2 Spire1 Spire1 Tex15 Tex15 Ep400 Ep400 Rnf169 Rnf169 Pml Pml Polq Polq Spidr Spidr Pogz Pogz Epc1 Epc1 Nsd2 Nsd2 Rpa2 Rpa2 LOC106023000 LOC106023000 Aunip Aunip ENSMAUP00000016870 ENSMAUP00000016870 Morf4l2 Morf4l2 Kat5 Kat5 Mrnip Mrnip Trrap Trrap ENSMAUP00000017580 ENSMAUP00000017580 Fignl1 Fignl1 Fbh1 Fbh1 Bcl7b Bcl7b Hmga2 Hmga2 LOC101843572 LOC101843572 Kmt5c Kmt5c Mrgbp Mrgbp Wdr48 Wdr48 Dtx3l Dtx3l Recql5 Recql5 Slf2 Slf2 Rmi2 Rmi2 ENSMAUP00000019481 ENSMAUP00000019481 Shld2 Shld2 Sirt7 Sirt7 Ogg1 Ogg1 Kdm1a Kdm1a ENSMAUP00000000943 ENSMAUP00000000943 Dmap1 Dmap1 Pnkp Pnkp Hsf1 Hsf1 Zcwpw1 Zcwpw1 Actl6a Actl6a Ubr5 Ubr5 Kmt5b Kmt5b ENSMAUP00000021193 ENSMAUP00000021193 Ppp4r3b Ppp4r3b Pot1 Pot1 Rad51 Rad51 Fancb Fancb Setmar Setmar Mad2l2 Mad2l2 Znf365 Znf365 Chek1 Chek1 Fam178b Fam178b Shld1 Shld1 Mbtd1 Mbtd1 Smchd1 Smchd1 Mms19 Mms19 Brd8 Brd8 Sirt6 Sirt6 Rtel1 Rtel1 Epc2 Epc2 Prkdc Prkdc Otub1 Otub1 Rif1 Rif1 Ruvbl1 Ruvbl1 Ddx11 Ddx11 ENSMAUP00000012929 ENSMAUP00000012929 Kdm4d Kdm4d Radx Radx Helq Helq Was Was ENSMAUP00000008841 ENSMAUP00000008841 Fus Fus Meaf6 Meaf6 Blm Blm Wrap53 Wrap53 Bcl7c Bcl7c Helb Helb Actb Actb ENSMAUP00000006748 ENSMAUP00000006748 Actr2 Actr2 Ercc6 Ercc6 Parp1 Parp1 Rbbp8 Rbbp8 Dek Dek Yeats4 Yeats4 Ubqln4 Ubqln4 Ube2v2 Ube2v2 Parpbp Parpbp Vps72 Vps72 Ube2n Ube2n Mgmt Mgmt Fh Fh Nudt16l1 Nudt16l1 ENSMAUP00000011610 ENSMAUP00000011610 Cyren Cyren Ing3 Ing3 Klhl15 Klhl15 Foxm1 Foxm1 Tp53bp1 Tp53bp1 Parp9 Parp9 Hdgfl2 Hdgfl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Slf1SMC5-SMC6 complex localization factor protein 1 isoform X1. (1061 aa)
Pias4E3 SUMO-protein ligase PIAS4 isoform X2. (508 aa)
Otub2Ubiquitin thioesterase. (236 aa)
Arid2AT-rich interactive domain-containing protein 2. (1766 aa)
Ppp4r2Serine/threonine-protein phosphatase 4 regulatory subunit 2. (365 aa)
Spire2Protein spire homolog 2 isoform X2. (720 aa)
TimelessProtein timeless homolog. (521 aa)
Rad51ap1RAD51-associated protein 1 isoform X1. (332 aa)
Ppp4cSerine/threonine-protein phosphatase. (307 aa)
Fmn2Formin-2. (1578 aa)
Parp3Poly [ADP-ribose] polymerase. (531 aa)
Setd2Histone-lysine N-methyltransferase SETD2. (2465 aa)
Morf4l1Mortality factor 4-like protein 1. (362 aa)
Ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (479 aa)
Spire1Protein spire homolog 1 isoform X2. (642 aa)
Tex15Testis-expressed protein 15. (2714 aa)
Ep400E1A-binding protein p400 isoform X9. (3062 aa)
Rnf169E3 ubiquitin-protein ligase RNF169. (694 aa)
PmlProtein PML isoform X1. (874 aa)
PolqDNA polymerase theta. (163 aa)
SpidrDNA repair-scaffolding protein isoform X1. (737 aa)
PogzPogo transposable element with ZNF domain isoform X1. (1410 aa)
Epc1Enhancer of polycomb homolog 1 isoform X2. (756 aa)
Nsd2Histone-lysine N-methyltransferase NSD2. (1367 aa)
Rpa2Replication protein A 32 kDa subunit. (270 aa)
LOC106023000DNA endonuclease RBBP8-like. (75 aa)
AunipAurora kinase A and ninein-interacting protein isoform X1. (345 aa)
ENSMAUP00000016870annotation not available (310 aa)
Morf4l2Mortality factor 4-like protein 2. (288 aa)
Kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (515 aa)
MrnipMRN complex-interacting protein. (316 aa)
TrrapTransformation/transcription domain-associated protein isoform X3; Belongs to the PI3/PI4-kinase family. (3860 aa)
ENSMAUP00000017580annotation not available (61 aa)
Fignl1Fidgetin-like protein 1 isoform X2; Belongs to the AAA ATPase family. (677 aa)
Fbh1F-box DNA helicase 1. (734 aa)
Bcl7bB-cell CLL/lymphoma 7 protein family member B isoform X2. (202 aa)
Hmga2High mobility group protein HMGI-C isoform X1. (108 aa)
LOC101843572F-box DNA helicase 1. (258 aa)
Kmt5cHistone-lysine N-methyltransferase KMT5C isoform X2. (474 aa)
MrgbpMRG/MORF4L-binding protein. (204 aa)
Wdr48WD repeat-containing protein 48 isoform X2. (678 aa)
Dtx3lE3 ubiquitin-protein ligase DTX3L. (738 aa)
Recql5ATP-dependent DNA helicase Q5. (977 aa)
Slf2SMC5-SMC6 complex localization factor protein 2 isoform X3. (1164 aa)
Rmi2recQ-mediated genome instability protein 2 isoform X2. (147 aa)
ENSMAUP00000019481annotation not available (257 aa)
Shld2Protein FAM35A isoform X2. (888 aa)
Sirt7NAD-dependent protein deacetylase sirtuin-7. (402 aa)
Ogg1N-glycosylase/DNA lyase. (203 aa)
Kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (870 aa)
ENSMAUP00000000943annotation not available (251 aa)
Dmap1DNA methyltransferase 1-associated protein 1. (468 aa)
PnkpBifunctional polynucleotide phosphatase/kinase isoform X2. (523 aa)
Hsf1Heat shock factor protein 1. (423 aa)
Zcwpw1Zinc finger CW-type PWWP domain protein 1. (442 aa)
Actl6aActin like 6A. (204 aa)
Ubr5E3 ubiquitin-protein ligase UBR5 isoform X2. (2798 aa)
Kmt5bHistone-lysine N-methyltransferase KMT5B. (883 aa)
ENSMAUP00000021193annotation not available (301 aa)
Ppp4r3bSerine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1. (820 aa)
Pot1Protection of telomeres protein 1. (639 aa)
Rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (187 aa)
FancbFanconi anemia group B protein isoform X1. (843 aa)
SetmarHistone-lysine N-methyltransferase SETMAR. (314 aa)
Mad2l2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
Znf365Protein ZNF365. (408 aa)
Chek1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
Fam178bProtein FAM178B isoform X2. (519 aa)
Shld1Uncharacterized protein C20orf196 homolog. (204 aa)
Mbtd1MBT domain-containing protein 1. (617 aa)
Smchd1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (2007 aa)
Mms19MMS19 nucleotide excision repair protein homolog isoform X1. (1031 aa)
Brd8Bromodomain-containing protein 8 isoform X4. (1154 aa)
Sirt6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (334 aa)
Rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1266 aa)
Epc2Enhancer of polycomb homolog. (109 aa)
PrkdcDNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3737 aa)
Otub1Ubiquitin thioesterase. (271 aa)
Rif1Telomere-associated protein RIF1. (2298 aa)
Ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
Ddx11ATP-dependent DNA helicase DDX11. (885 aa)
ENSMAUP00000012929annotation not available (90 aa)
Kdm4dLysine-specific demethylase 4D. (521 aa)
RadxUncharacterized protein CXorf57 homolog. (849 aa)
HelqHelicase POLQ-like. (925 aa)
Waswiskott-Aldrich syndrome protein. (515 aa)
ENSMAUP00000008841annotation not available (286 aa)
FusRNA-binding protein FUS isoform X1. (517 aa)
Meaf6Chromatin modification-related protein MEAF6. (171 aa)
BlmBloom syndrome protein. (1415 aa)
Wrap53Telomerase Cajal body protein 1; RNA chaperone that plays a key role in telomere maintenance and RNA localization to Cajal bodies. Specifically recognizes and binds the Cajal body box (CAB box) present in both small Cajal body RNAs (scaRNAs) and telomerase RNA template component (TERC). Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, required to stimulate the catalytic activity of the complex. Acts by specifically b [...] (538 aa)
Bcl7cB-cell CLL/lymphoma 7 protein family member C isoform X4. (217 aa)
HelbDNA helicase B. (1060 aa)
ActbActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
ENSMAUP00000006748annotation not available (119 aa)
Actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (380 aa)
Ercc6DNA excision repair protein ERCC-6. (1236 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
Rbbp8DNA endonuclease RBBP8 isoform X1. (813 aa)
DekProtein DEK. (395 aa)
Yeats4YEATS domain-containing protein 4. (227 aa)
Ubqln4Ubiquilin-4 isoform X1. (595 aa)
Ube2v2Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. (146 aa)
ParpbpPCNA-interacting partner isoform X1. (573 aa)
Vps72LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 72 homolog. (317 aa)
Ube2nUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
Mgmtmethylated-DNA--protein-cysteine methyltransferase. (212 aa)
FhFumarate hydratase, mitochondrial. (507 aa)
Nudt16l1Tudor-interacting repair regulator protein. (211 aa)
ENSMAUP00000011610annotation not available (261 aa)
CyrenModulator of retrovirus infection homolog. (154 aa)
Ing3Inhibitor of growth protein. (419 aa)
Klhl15Kelch-like protein 15. (604 aa)
Foxm1Forkhead box protein M1 isoform X2. (764 aa)
Tp53bp1TP53-binding protein 1 isoform X2. (716 aa)
Parp9Poly (ADP-ribose) polymerase family, member 9. (695 aa)
Hdgfl2Hepatoma-derived growth factor-related protein 2 isoform X1. (99 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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