(46 nodes) FERM superfamily, second domain network (Mesocricetus auratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Ptk2	Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (667 aa)
	Tln1	Talin-1. (2541 aa)
	Ptpn4	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
	Frmd3	FERM domain-containing protein 3. (547 aa)
	Frmpd1	FERM and PDZ domain-containing protein 1. (1537 aa)
	Epb41l2	Band 4.1-like protein 2 isoform X11. (999 aa)
	Ptpn3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (785 aa)
	Ptpn13	LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 13. (2300 aa)
	Frmpd2	FERM and PDZ domain-containing protein 2. (303 aa)
	Myo7a	Unconventional myosin-VIIa isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2177 aa)
	Nf2	Merlin isoform X1. (596 aa)
	Ptpn14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (999 aa)
	Fermt1	Fermitin family homolog 1 isoform X1. (677 aa)
	Jak1	Tyrosine-protein kinase. (1161 aa)
	Jak2	Tyrosine-protein kinase. (1132 aa)
	Frmd4b	LOW QUALITY PROTEIN: FERM domain-containing protein 4B. (682 aa)
	Ezr	Ezrin. (576 aa)
	Epb41l1	Band 4.1-like protein 1 isoform X6. (856 aa)
	Plekhh3	Pleckstrin homology domain-containing family H member 3 isoform X1. (794 aa)
	Msn	Moesin. (579 aa)
	Frmpd4	FERM and PDZ domain-containing protein 4 isoform X2. (1320 aa)
	Frmd4a	FERM domain-containing protein 4A isoform X3. (1036 aa)
	Ptk2b	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	Frmd5	FERM domain-containing protein 5 isoform X3. (570 aa)
	Myo10	Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2060 aa)
	Tyk2	Tyrosine-protein kinase. (1190 aa)
	Frmd8	FERM domain-containing protein 8 isoform X1. (464 aa)
	Myo15b	Myosin XVB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (512 aa)
	Plekhh2	Pleckstrin homology domain-containing family H member 2. (1489 aa)
	Myo15	Unconventional myosin-XV; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3481 aa)
	Frmpd3	FERM and PDZ domain-containing protein 3 isoform X1. (1768 aa)
	Epb41l5	Band 4.1-like protein 5 isoform X1. (114 aa)
	Fermt2	Fermitin family homolog 2 isoform X6. (680 aa)
	Frmd6	FERM domain-containing protein 6 isoform X1. (619 aa)
	Fermt3	Fermitin family homolog 3. (665 aa)
	Mylip	E3 ubiquitin-protein ligase MYLIP isoform X1. (445 aa)
	Rdx	Radixin. (564 aa)
	Farp2	FERM, RhoGEF and pleckstrin domain-containing protein 2. (1062 aa)
	Ptpn21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (336 aa)
	Krit1	LOW QUALITY PROTEIN: krev interaction trapped protein 1. (728 aa)
	Farp1	FERM, RhoGEF and pleckstrin domain-containing protein 1. (269 aa)
	Myo7b	Unconventional myosin-VIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2071 aa)
	Epb41l3	Band 4.1-like protein 3. (913 aa)
	Epb41l4a	Band 4.1-like protein 4A. (655 aa)
	Plekhh1	Pleckstrin homology domain-containing family H member 1. (1355 aa)
	Tln2	Talin-2 isoform X2. (2542 aa)

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Epb41l1	Epb41l2	ENSMAUP00000004021	ENSMAUP00000001506	Band 4.1-like protein 1 isoform X6.	Band 4.1-like protein 2 isoform X11.	0.760
Epb41l1	Epb41l3	ENSMAUP00000004021	ENSMAUP00000011182	Band 4.1-like protein 1 isoform X6.	Band 4.1-like protein 3.	0.736
Epb41l1	Epb41l4a	ENSMAUP00000004021	ENSMAUP00000010828	Band 4.1-like protein 1 isoform X6.	Band 4.1-like protein 4A.	0.552
Epb41l1	Epb41l5	ENSMAUP00000004021	ENSMAUP00000017671	Band 4.1-like protein 1 isoform X6.	Band 4.1-like protein 5 isoform X1.	0.558
Epb41l1	Ezr	ENSMAUP00000004021	ENSMAUP00000005409	Band 4.1-like protein 1 isoform X6.	Ezrin.	0.648
Epb41l1	Farp1	ENSMAUP00000004021	ENSMAUP00000012782	Band 4.1-like protein 1 isoform X6.	FERM, RhoGEF and pleckstrin domain-containing protein 1.	0.724
Epb41l1	Msn	ENSMAUP00000004021	ENSMAUP00000004934	Band 4.1-like protein 1 isoform X6.	Moesin.	0.631
Epb41l1	Rdx	ENSMAUP00000004021	ENSMAUP00000014379	Band 4.1-like protein 1 isoform X6.	Radixin.	0.631
Epb41l2	Epb41l1	ENSMAUP00000001506	ENSMAUP00000004021	Band 4.1-like protein 2 isoform X11.	Band 4.1-like protein 1 isoform X6.	0.760
Epb41l2	Epb41l3	ENSMAUP00000001506	ENSMAUP00000011182	Band 4.1-like protein 2 isoform X11.	Band 4.1-like protein 3.	0.807
Epb41l2	Epb41l4a	ENSMAUP00000001506	ENSMAUP00000010828	Band 4.1-like protein 2 isoform X11.	Band 4.1-like protein 4A.	0.552
Epb41l2	Epb41l5	ENSMAUP00000001506	ENSMAUP00000017671	Band 4.1-like protein 2 isoform X11.	Band 4.1-like protein 5 isoform X1.	0.558
Epb41l2	Ezr	ENSMAUP00000001506	ENSMAUP00000005409	Band 4.1-like protein 2 isoform X11.	Ezrin.	0.424
Epb41l2	Msn	ENSMAUP00000001506	ENSMAUP00000004934	Band 4.1-like protein 2 isoform X11.	Moesin.	0.440
Epb41l2	Rdx	ENSMAUP00000001506	ENSMAUP00000014379	Band 4.1-like protein 2 isoform X11.	Radixin.	0.424
Epb41l3	Epb41l1	ENSMAUP00000011182	ENSMAUP00000004021	Band 4.1-like protein 3.	Band 4.1-like protein 1 isoform X6.	0.736
Epb41l3	Epb41l2	ENSMAUP00000011182	ENSMAUP00000001506	Band 4.1-like protein 3.	Band 4.1-like protein 2 isoform X11.	0.807
Epb41l3	Epb41l4a	ENSMAUP00000011182	ENSMAUP00000010828	Band 4.1-like protein 3.	Band 4.1-like protein 4A.	0.552
Epb41l3	Epb41l5	ENSMAUP00000011182	ENSMAUP00000017671	Band 4.1-like protein 3.	Band 4.1-like protein 5 isoform X1.	0.558
Epb41l3	Ezr	ENSMAUP00000011182	ENSMAUP00000005409	Band 4.1-like protein 3.	Ezrin.	0.472

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