STRINGSTRING
Tcf21 Tcf21 Myf5 Myf5 Nhlh1 Nhlh1 Id1 Id1 Stra8 Stra8 Npas1 Npas1 Id4 Id4 Tfec Tfec Tfe3 Tfe3 Twist2 Twist2 Tcf23 Tcf23 Mesp1 Mesp1 Mitf Mitf Neurog2 Neurog2 Neurod2 Neurod2 Ascl3 Ascl3 Mxd1 Mxd1 Olig3 Olig3 Myc Myc Tal2 Tal2 Atoh8 Atoh8 Neurod6 Neurod6 Bhlhe23 Bhlhe23 Arntl Arntl Bhlhe40 Bhlhe40 Bhlha9 Bhlha9 Atoh7 Atoh7 Ncoa3 Ncoa3 Bhlhe22 Bhlhe22 Ptf1a Ptf1a Neurog3 Neurog3 Mlx Mlx Mxd3 Mxd3 Hey2 Hey2 Tcf24 Tcf24 Mlxip Mlxip Hif3a Hif3a Tfeb Tfeb Olig2 Olig2 Clock Clock Sim2 Sim2 Hes7 Hes7 Mxi1 Mxi1 Id2 Id2 Figla Figla Hand2 Hand2 Max Max Usf2 Usf2 Npas2 Npas2 Hes1 Hes1 Usf1 Usf1 Myod1 Myod1 Mxd4 Mxd4 Mnt Mnt Srebf2 Srebf2 Msc Msc Arnt2 Arnt2 Epas1 Epas1 Tcf4 Tcf4 Arntl2 Arntl2 Tcfl5 Tcfl5 Bhlhe41 Bhlhe41 Usf3 Usf3 Msgn1 Msgn1 Srebf1 Srebf1 Neurod1 Neurod1 Ferd3l Ferd3l Atoh1 Atoh1 Tcf3 Tcf3 Neurod4 Neurod4 Ncoa1 Ncoa1 Nhlh2 Nhlh2 Sohlh2 Sohlh2 Mycn Mycn Neurog1 Neurog1 Hes3 Hes3 Ncoa2 Ncoa2 Ahrr Ahrr Ahr Ahr Hey1 Hey1 Ascl2 Ascl2 Myf6 Myf6 Tfap4 Tfap4 Sohlh1 Sohlh1 Mlxipl Mlxipl Myog Myog Mycl Mycl Hes5 Hes5 Hes2 Hes2 Hif1a Hif1a Ascl1 Ascl1 Mga Mga Id3 Id3 Hes6 Hes6 Helt Helt Sim1 Sim1 Heyl Heyl Tcf15 Tcf15 Hand1 Hand1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tcf21Transcription factor 21. (179 aa)
Myf5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
Nhlh1Helix-loop-helix protein 1. (133 aa)
Id1DNA-binding protein inhibitor ID-1 isoform X2. (151 aa)
Stra8Stimulated by retinoic acid gene 8 protein homolog. (344 aa)
Npas1Neuronal PAS domain-containing protein 1 isoform X1. (595 aa)
Id4DNA-binding protein inhibitor ID-4. (161 aa)
TfecTranscription factor EC. (317 aa)
Tfe3Transcription factor E3 isoform X4. (573 aa)
Twist2Twist-related protein 2. (160 aa)
Tcf23Transcription factor 23 isoform X2. (208 aa)
Mesp1Mesoderm posterior protein 1. (246 aa)
MitfMicrophthalmia-associated transcription factor isoform X1. (526 aa)
Neurog2Neurogenin-2. (267 aa)
Neurod2Neurogenic differentiation factor. (382 aa)
Ascl3Achaete-scute homolog 3. (174 aa)
Mxd1Max dimerization protein 1. (222 aa)
Olig3Oligodendrocyte transcription factor 3. (273 aa)
MycMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
Tal2T-cell acute lymphocytic leukemia protein 2. (108 aa)
Atoh8Protein atonal homolog 8. (320 aa)
Neurod6Neurogenic differentiation factor. (337 aa)
Bhlhe23Class E basic helix-loop-helix protein 23. (223 aa)
ArntlAryl hydrocarbon receptor nuclear translocator-like protein 1; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] (626 aa)
Bhlhe40Class E basic helix-loop-helix protein 40. (411 aa)
Bhlha9Class A basic helix-loop-helix protein 9. (230 aa)
Atoh7Protein atonal homolog 7. (150 aa)
Ncoa3Nuclear receptor coactivator. (1409 aa)
Bhlhe22Class E basic helix-loop-helix protein 22; Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA. (365 aa)
Ptf1aPancreas transcription factor 1 subunit alpha. (324 aa)
Neurog3Neurogenin-3. (214 aa)
MlxMax-like protein X isoform X1. (298 aa)
Mxd3Max dimerization protein 3. (206 aa)
Hey2Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
Tcf24Transcription factor 24. (165 aa)
MlxipMLX-interacting protein. (812 aa)
Hif3aHypoxia-inducible factor 3-alpha isoform X1. (666 aa)
TfebTranscription factor EB isoform X1. (472 aa)
Olig2Oligodendrocyte transcription factor 2. (322 aa)
ClockCircadian locomoter output cycles protein kaput. (824 aa)
Sim2Single-minded homolog 2. (622 aa)
Hes7Transcription factor HES-7 isoform X3. (225 aa)
Mxi1Max-interacting protein 1. (280 aa)
Id2DNA-binding protein inhibitor ID-2. (134 aa)
FiglaFactor in the germline alpha isoform X1. (203 aa)
Hand2Heart- and neural crest derivatives-expressed protein 2. (217 aa)
MaxProtein max isoform X1. (160 aa)
Usf2Upstream stimulatory factor 2. (339 aa)
Npas2Neuronal PAS domain-containing protein 2. (60 aa)
Hes1Transcription factor HES-1. (281 aa)
Usf1Upstream stimulatory factor 1 isoform X1. (310 aa)
Myod1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (318 aa)
Mxd4Max dimerization protein 4. (209 aa)
MntMax-binding protein MNT. (588 aa)
Srebf2Sterol regulatory element-binding protein 2. (958 aa)
MscMusculin. (192 aa)
Arnt2Aryl hydrocarbon receptor nuclear translocator 2 isoform X1. (712 aa)
Epas1Endothelial PAS domain-containing protein 1. (784 aa)
Tcf4Transcription factor 4. (670 aa)
Arntl2Aryl hydrocarbon receptor nuclear translocator-like protein 2. (550 aa)
Tcfl5Transcription factor-like 5 protein. (357 aa)
Bhlhe41Class E basic helix-loop-helix protein 41. (94 aa)
Usf3Basic helix-loop-helix domain-containing protein USF3. (2157 aa)
Msgn1Mesogenin-1. (188 aa)
Srebf1Sterol regulatory element-binding protein 1 isoform X1. (1130 aa)
Neurod1Neurogenic differentiation factor 1; Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or [...] (355 aa)
Ferd3lFer3-like protein. (168 aa)
Atoh1Protein atonal homolog 1. (351 aa)
Tcf3Transcription factor E2-alpha; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region (By similarity). (633 aa)
Neurod4Neurogenic differentiation factor. (331 aa)
Ncoa1Nuclear receptor coactivator. (1444 aa)
Nhlh2Helix-loop-helix protein 2. (135 aa)
Sohlh2Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2. (466 aa)
MycnLOW QUALITY PROTEIN: N-myc proto-oncogene protein. (462 aa)
Neurog1Neurogenin-1. (241 aa)
Hes3Transcription factor HES-3. (176 aa)
Ncoa2Nuclear receptor coactivator. (1475 aa)
AhrrAryl hydrocarbon receptor repressor. (702 aa)
AhrAryl hydrocarbon receptor. (731 aa)
Hey1Hairy/enhancer-of-split related with YRPW motif protein 1. (278 aa)
Ascl2Achaete-scute homolog 2. (193 aa)
Myf6Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (242 aa)
Tfap4Transcription factor AP-4. (316 aa)
Sohlh1Spermatogenesis and oogenesis specific basic helix-loop-helix 1. (342 aa)
MlxiplCarbohydrate-responsive element-binding protein isoform X1. (859 aa)
MyogMyogenin. (224 aa)
MyclProtein L-Myc. (368 aa)
Hes5Transcription factor HES-5. (166 aa)
Hes2Transcription factor HES-2. (157 aa)
Hif1aHypoxia-inducible factor 1-alpha isoform X1. (246 aa)
Ascl1Achaete-scute homolog 1. (234 aa)
MgaMAX gene-associated protein isoform X2. (3033 aa)
Id3DNA-binding protein inhibitor ID-3. (119 aa)
Hes6Transcription cofactor HES-6. (224 aa)
HeltHairy and enhancer of split-related protein HELT isoform X1. (241 aa)
Sim1Single-minded homolog 1. (765 aa)
HeylHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa)
Tcf15Transcription factor 15; May function as an early transcriptional regulator, involved in the patterning of the mesoderm and in lineage determination of cell types derived from the mesoderm. (195 aa)
Hand1Heart- and neural crest derivatives-expressed protein 1. (215 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (16%) [HD]