STRINGSTRING
ENSMAUP00000007258 ENSMAUP00000007258 LOC101823019 LOC101823019 Rps27a Rps27a Kxd1 Kxd1 Rnf41 Rnf41 Nrg1 Nrg1 Erbb2 Erbb2 Akt2 Akt2 Usp8 Usp8 ENSMAUP00000022314 ENSMAUP00000022314 ENSMAUP00000019431 ENSMAUP00000019431 Akt3 Akt3 Akt1 Akt1 Nrg2 Nrg2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAUP00000007258annotation not available (117 aa)
LOC101823019Ubiquitin-like. (114 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Rnf41E3 ubiquitin-protein ligase NRDP1 isoform X2. (317 aa)
Nrg1Pro-neuregulin-1, membrane-bound isoform. (655 aa)
Erbb2Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...] (1247 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Usp8Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1070 aa)
ENSMAUP00000022314annotation not available (101 aa)
ENSMAUP00000019431annotation not available (150 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Nrg2Pro-neuregulin-2, membrane-bound isoform. (279 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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