STRINGSTRING
Fbxo5 Fbxo5 Fzr1 Fzr1 LOC101832726 LOC101832726 Cdc16 Cdc16 Ccnb1 Ccnb1 Skp1 Skp1 ENSMAUP00000002256 ENSMAUP00000002256 Kxd1 Kxd1 Ube2c Ube2c ENSMAUP00000004398 ENSMAUP00000004398 Rps27a Rps27a LOC101823019 LOC101823019 Cul1 Cul1 ENSMAUP00000007258 ENSMAUP00000007258 ENSMAUP00000007836 ENSMAUP00000007836 Anapc16 Anapc16 Anapc7 Anapc7 ENSMAUP00000009902 ENSMAUP00000009902 Fbxo43 Fbxo43 Anapc2 Anapc2 Mad2l1 Mad2l1 Ccna1 Ccna1 Plk1 Plk1 Cdc20 Cdc20 Cdc27 Cdc27 Ube2s Ube2s Cdk3 Cdk3 Anapc10 Anapc10 Tm7sf3 Tm7sf3 Ube2e1 Ube2e1 Fam89b Fam89b ENSMAUP00000016715 ENSMAUP00000016715 Anapc4 Anapc4 Btrc Btrc LOC101837857 LOC101837857 Fam89a Fam89a ENSMAUP00000019431 ENSMAUP00000019431 Anapc5 Anapc5 Ccna2 Ccna2 Anapc1 Anapc1 Bub3 Bub3 Anapc11 Anapc11 Anapc15 Anapc15 Cdk2 Cdk2 Cdc26 Cdc26 ENSMAUP00000022314 ENSMAUP00000022314 Cdk1 Cdk1 ENSMAUP00000024812 ENSMAUP00000024812 Bub1b Bub1b Cdc23 Cdc23 Ube2d1 Ube2d1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fbxo5F-box only protein 5. (424 aa)
Fzr1Fizzy-related protein homolog. (493 aa)
LOC101832726S-phase kinase-associated protein 1 pseudogene. (144 aa)
Cdc16Cell division cycle protein 16 homolog isoform X1. (620 aa)
Ccnb1G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (447 aa)
Skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (158 aa)
ENSMAUP00000002256annotation not available (75 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Ube2cUbiquitin-conjugating enzyme E2C. (135 aa)
ENSMAUP00000004398annotation not available (164 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC101823019Ubiquitin-like. (114 aa)
Cul1Cullin-1; Belongs to the cullin family. (776 aa)
ENSMAUP00000007258annotation not available (117 aa)
ENSMAUP00000007836annotation not available (57 aa)
Anapc16Anaphase-promoting complex subunit 16. (94 aa)
Anapc7Anaphase-promoting complex subunit 7. (540 aa)
ENSMAUP00000009902annotation not available (163 aa)
Fbxo43F-box only protein 43 isoform X1. (634 aa)
Anapc2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (833 aa)
Mad2l1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
Ccna1cyclin-A1; Belongs to the cyclin family. (421 aa)
Plk1Serine/threonine-protein kinase PLK. (602 aa)
Cdc20Cell division cycle protein 20 homolog. (499 aa)
Cdc27Cell division cycle protein 27 homolog. (680 aa)
Ube2sUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (221 aa)
Cdk3Cyclin-dependent kinase 3 isoform X2; Belongs to the protein kinase superfamily. (297 aa)
Anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
Tm7sf3Transmembrane 7 superfamily member 3. (493 aa)
Ube2e1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
Fam89bProtein FAM89B. (189 aa)
ENSMAUP00000016715annotation not available (418 aa)
Anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa)
BtrcF-box/WD repeat-containing protein 1A isoform X2. (605 aa)
LOC101837857Cell division cycle protein 27 homolog. (204 aa)
Fam89aProtein FAM89A. (183 aa)
ENSMAUP00000019431annotation not available (150 aa)
Anapc5Anaphase-promoting complex subunit 5. (84 aa)
Ccna2Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. Belongs to the cyclin family. Cyclin AB subfamily. (421 aa)
Anapc1Anaphase-promoting complex subunit 1. (1666 aa)
Bub3Mitotic checkpoint protein BUB3. (326 aa)
Anapc11Anaphase-promoting complex subunit 11. (47 aa)
Anapc15Anaphase-promoting complex subunit 15 isoform X1. (141 aa)
Cdk2Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa)
Cdc26Anaphase-promoting complex subunit CDC26. (85 aa)
ENSMAUP00000022314annotation not available (101 aa)
Cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
ENSMAUP00000024812annotation not available (115 aa)
Bub1bMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1011 aa)
Cdc23Cell division cycle protein 23 homolog. (580 aa)
Ube2d1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.