STRINGSTRING
Sh3gl2 Sh3gl2 Cbl Cbl Eps15 Eps15 ENSMAUP00000022314 ENSMAUP00000022314 Tgfa Tgfa ENSMAUP00000019431 ENSMAUP00000019431 Arhgef7 Arhgef7 Sh3kbp1 Sh3kbp1 Spry1 Spry1 Hgs Hgs Egf Egf Ereg Ereg Ptprm Ptprm Areg Areg Sh3gl1 Sh3gl1 Eps15l1 Eps15l1 Epn1 Epn1 ENSMAUP00000007258 ENSMAUP00000007258 Sh3gl3 Sh3gl3 Ptprt Ptprt LOC101823019 LOC101823019 Rps27a Rps27a ENSMAUP00000005829 ENSMAUP00000005829 Cdc42 Cdc42 Kxd1 Kxd1 Btc Btc Stam2 Stam2 Spry2 Spry2 Ptprk Ptprk Egfr Egfr Stam Stam Ptpn3 Ptpn3 ENSMAUP00000001986 ENSMAUP00000001986 ENSMAUP00000002256 ENSMAUP00000002256 Grb2 Grb2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sh3gl2endophilin-A1. (347 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
Eps15Epidermal growth factor receptor substrate 15 isoform X2. (898 aa)
ENSMAUP00000022314annotation not available (101 aa)
TgfaProtransforming growth factor alpha. (159 aa)
ENSMAUP00000019431annotation not available (150 aa)
Arhgef7Rho guanine nucleotide exchange factor 7 isoform X2. (862 aa)
Sh3kbp1SH3 domain-containing kinase-binding protein 1. (445 aa)
Spry1Protein sprouty homolog 1. (313 aa)
HgsHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (775 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (254 aa)
EregProepiregulin. (162 aa)
PtprmReceptor-type tyrosine-protein phosphatase mu. (929 aa)
AregAmphiregulin. (248 aa)
Sh3gl1endophilin-A2. (368 aa)
Eps15l1Epidermal growth factor receptor substrate 15-like 1. (601 aa)
Epn1Epsin-1 isoform X1. (576 aa)
ENSMAUP00000007258annotation not available (117 aa)
Sh3gl3endophilin-A3 isoform X1. (347 aa)
PtprtReceptor-type tyrosine-protein phosphatase T. (949 aa)
LOC101823019Ubiquitin-like. (114 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
ENSMAUP00000005829annotation not available (329 aa)
Cdc42Cell division control protein 42 homolog isoform X1. (191 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
BtcProbetacellulin. (175 aa)
Stam2Signal transducing adapter molecule 2 isoform X1. (524 aa)
Spry2Protein sprouty homolog 2. (320 aa)
PtprkReceptor-type tyrosine-protein phosphatase kappa isoform X10. (1456 aa)
EgfrReceptor protein-tyrosine kinase. (1207 aa)
StamSignal transducing adapter molecule 1. (462 aa)
Ptpn3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (785 aa)
ENSMAUP00000001986annotation not available (342 aa)
ENSMAUP00000002256annotation not available (75 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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