STRINGSTRING
Kl Kl Sos1 Sos1 Spry2 Spry2 Fgf18 Fgf18 Ptbp3 Ptbp3 Polr2c Polr2c Polr2i Polr2i Plcg1 Plcg1 Mknk1 Mknk1 Fndc3b Fndc3b Cbl Cbl Ncbp2 Ncbp2 Fgfbp1 Fgfbp1 Spred1 Spred1 Polr2a Polr2a Tia1 Tia1 Ncbp1 Ncbp1 ENSMAUP00000022912 ENSMAUP00000022912 Fgf6 Fgf6 Hras Hras Nras Nras Shc1 Shc1 Pik3ca Pik3ca ENSMAUP00000022314 ENSMAUP00000022314 ENSMAUP00000002256 ENSMAUP00000002256 Kxd1 Kxd1 ENSMAUP00000003314 ENSMAUP00000003314 Esrp2 Esrp2 Ppp2r1a Ppp2r1a Galnt3 Galnt3 Fgfbp3 Fgfbp3 Eras Eras Rps27a Rps27a Pik3r1 Pik3r1 Ptbp1 Ptbp1 LOC101823019 LOC101823019 ENSMAUP00000006881 ENSMAUP00000006881 LOC101833993 LOC101833993 Fgf23 Fgf23 ENSMAUP00000007258 ENSMAUP00000007258 Gtf2f1 Gtf2f1 LOC101827110 LOC101827110 Flrt3 Flrt3 Ppp2ca Ppp2ca Src Src Polr2e Polr2e Polr2k Polr2k Mknk2 Mknk2 LOC101840076 LOC101840076 ENSMAUP00000009986 ENSMAUP00000009986 Fgf20 Fgf20 ENSMAUP00000010327 ENSMAUP00000010327 Fndc3a Fndc3a Fgfr4 Fgfr4 Fgf1 Fgf1 Fgf10 Fgf10 Mapk3 Mapk3 Fgfr2 Fgfr2 Fgfr3 Fgfr3 Polr2j Polr2j Polr2g Polr2g Spred2 Spred2 Fgf7 Fgf7 Ptpn11 Ptpn11 Csde1 Csde1 Klb Klb Frs3 Frs3 Polr2d Polr2d Fgf2 Fgf2 Fgf17 Fgf17 Gtf2f1-2 Gtf2f1-2 Flrt1 Flrt1 Fgf22 Fgf22 Braf Braf Polr2h Polr2h Fgf8 Fgf8 Fgf5 Fgf5 Grb2 Grb2 Mapk1 Mapk1 Kras Kras Esrp1 Esrp1 Hnrnpm Hnrnpm Fgf3 Fgf3 Polr2b Polr2b ENSMAUP00000019431 ENSMAUP00000019431 Frs2 Frs2 Flrt2 Flrt2 Fgfrl1 Fgfrl1 Fgfr1 Fgfr1 Fgf16 Fgf16 Fgf19 Fgf19 Fgf4 Fgf4 Polr2f Polr2f Stil Stil Rbfox2 Rbfox2 Gtf2f2 Gtf2f2 Ppp2cb Ppp2cb Polr2l Polr2l Ptbp2 Ptbp2 ENSMAUP00000021238 ENSMAUP00000021238 ENSMAUP00000021418 ENSMAUP00000021418 Hnrnpa1 Hnrnpa1 Fgf9 Fgf9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KlKlotho. (1014 aa)
Sos1Son of sevenless homolog 1. (1319 aa)
Spry2Protein sprouty homolog 2. (320 aa)
Fgf18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
Ptbp3Polypyrimidine tract-binding protein 3. (524 aa)
Polr2cDNA-directed RNA polymerase II subunit RPB3. (250 aa)
Polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1293 aa)
Mknk1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (415 aa)
Fndc3bFibronectin type III domain-containing protein 3B isoform X1. (1206 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
Ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
Fgfbp1Fibroblast growth factor-binding protein 1. (248 aa)
Spred1Sprouty-related, EVH1 domain-containing protein 1. (446 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (987 aa)
Tia1Nucleolysin TIA-1 isoform X2. (387 aa)
Ncbp1Nuclear cap-binding protein subunit 1. (789 aa)
ENSMAUP00000022912annotation not available (508 aa)
Fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
HrasGTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
NrasNRAS proto-oncogene, GTPase. (98 aa)
Shc1SHC-transforming protein 1 isoform X1. (579 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ENSMAUP00000022314annotation not available (101 aa)
ENSMAUP00000002256annotation not available (75 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
ENSMAUP00000003314annotation not available (266 aa)
Esrp2Epithelial splicing regulatory protein 2 isoform X1. (717 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
Galnt3Polypeptide N-acetylgalactosaminyltransferase. (634 aa)
Fgfbp3Fibroblast growth factor-binding protein 3. (251 aa)
ErasGTPase ERas. (228 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Ptbp1Polypyrimidine tract-binding protein 1. (545 aa)
LOC101823019Ubiquitin-like. (114 aa)
ENSMAUP00000006881annotation not available (95 aa)
LOC101833993Nucleolysin TIAR. (235 aa)
Fgf23Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
ENSMAUP00000007258annotation not available (117 aa)
Gtf2f1General transcription factor IIF subunit 1. (280 aa)
LOC101827110Fibronectin type III domain containing protein 3C1-like. (1355 aa)
Flrt3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
Ppp2caSerine/threonine-protein phosphatase. (309 aa)
SrcTyrosine-protein kinase. (536 aa)
Polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1. (216 aa)
Polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
Mknk2MAP kinase-interacting serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily. (459 aa)
LOC101840076DNA-directed RNA polymerase II subunit RPB1. (543 aa)
ENSMAUP00000009986annotation not available (173 aa)
Fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
ENSMAUP00000010327annotation not available (476 aa)
Fndc3aFibronectin type-III domain-containing protein 3A. (1171 aa)
Fgfr4Fibroblast growth factor receptor. (794 aa)
Fgf1Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with int [...] (155 aa)
Fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Fgfr2Fibroblast growth factor receptor. (784 aa)
Fgfr3Fibroblast growth factor receptor. (802 aa)
Polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
Polr2gDNA-directed RNA polymerase II subunit RPB7. (94 aa)
Spred2Sprouty-related, EVH1 domain-containing protein 2 isoform X2. (438 aa)
Fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
Csde1Cold shock domain-containing protein E1 isoform X3. (798 aa)
KlbLOW QUALITY PROTEIN: beta-klotho. (1043 aa)
Frs3Fibroblast growth factor receptor substrate 3. (495 aa)
Polr2dDNA-directed RNA polymerase II subunit RPB4. (142 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
Fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
Gtf2f1-2Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (242 aa)
Flrt1Leucine-rich repeat transmembrane protein FLRT1. (674 aa)
Fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (162 aa)
BrafSerine/threonine-protein kinase B-raf. (710 aa)
Polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
Fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
Fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
KrasGTPase KRas isoform X3. (189 aa)
Esrp1Epithelial splicing regulatory protein 1 isoform X1. (667 aa)
HnrnpmHeterogeneous nuclear ribonucleoprotein M isoform X1. (730 aa)
Fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
Polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1175 aa)
ENSMAUP00000019431annotation not available (150 aa)
Frs2Fibroblast growth factor receptor substrate 2. (510 aa)
Flrt2Leucine-rich repeat transmembrane protein FLRT2. (660 aa)
Fgfrl1Fibroblast growth factor receptor-like 1 isoform X1. (533 aa)
Fgfr1Fibroblast growth factor receptor. (819 aa)
Fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
Fgf19Fibroblast growth factor 19; Belongs to the heparin-binding growth factors family. (215 aa)
Fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (52 aa)
Polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X2. (127 aa)
StilSCL-interrupting locus protein. (894 aa)
Rbfox2RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (378 aa)
Gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
Ppp2cbProtein phosphatase 2 catalytic subunit beta. (299 aa)
Polr2lDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
Ptbp2Polypyrimidine tract-binding protein 2 isoform X3. (532 aa)
ENSMAUP00000021238annotation not available (247 aa)
ENSMAUP00000021418annotation not available (290 aa)
Hnrnpa1Heterogeneous nuclear ribonucleoprotein A1 isoform X2. (320 aa)
Fgf9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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