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Cyp46a1 Cyp46a1 Cyp27a1 Cyp27a1 Akr1d1 Akr1d1 Slc27a5 Slc27a5 Sugct Sugct Hsd3b7 Hsd3b7 Amacr Amacr Cyp8b1 Cyp8b1 LOC101843587 LOC101843587 LOC101841267 LOC101841267 LOC101839651 LOC101839651 Slc27a2 Slc27a2 Akr1c14 Akr1c14 LOC101843311 LOC101843311 LOC101842245 LOC101842245 Cyp39a1 Cyp39a1 Akr1c19 Akr1c19 Akr1c18 Akr1c18 LOC101842874 LOC101842874
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Cyp46a1Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (500 aa)
Cyp27a1Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (534 aa)
Akr1d13-oxo-5-beta-steroid 4-dehydrogenase. (325 aa)
Slc27a5Bile acyl-CoA synthetase. (690 aa)
SugctSuccinate--hydroxymethylglutarate CoA-transferase isoform X1. (436 aa)
Hsd3b73 beta-hydroxysteroid dehydrogenase type 7 isoform X1; Belongs to the 3-beta-HSD family. (369 aa)
Amacralpha-methylacyl-CoA racemase isoform X1. (382 aa)
Cyp8b17-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
LOC101843587Aldo-keto reductase family 1 member C21-like isoform X1. (319 aa)
LOC101841267prostaglandin-E(2) 9-reductase-like isoform X2. (311 aa)
LOC101839651Aldo-keto reductase family 1 member C21-like. (310 aa)
Slc27a2Very long-chain acyl-CoA synthetase. (620 aa)
Akr1c143-alpha-hydroxysteroid dehydrogenase-like isoform X1. (323 aa)
LOC1018433113-hydroxyhexobarbital dehydrogenase 1/3-alpha, 17-beta-hydroxysteroid dehydrogenase. (323 aa)
LOC101842245Aldo-keto reductase family 1 member C13-like isoform X1. (311 aa)
Cyp39a124-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (377 aa)
Akr1c19Aldo-keto reductase family 1 member C13-like. (251 aa)
Akr1c18Aldo-keto reductase family 1 member C18 isoform X1. (323 aa)
LOC101842874Aldo-keto reductase family 1 member C13; Catalyzes the dehydrogenation of morphine to morphinone. The enzyme also exhibits significant activity for a variety of cyclic and alicyclic alcohols. In addition to xenobiotics, the enzyme catalyzes the dehydrogenation of 17-beta-hydroxysteroids with much higher affinities than morphine. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP. (323 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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