STRINGSTRING
Adh5 Adh5 LOC101825889 LOC101825889 Ces2h Ces2h Cbr3 Cbr3 Inmt Inmt Ces5a Ces5a Hpgds Hpgds LOC101822730 LOC101822730 LOC101822554 LOC101822554 LOC101831088 LOC101831088 Bphl Bphl LOC101833813 LOC101833813 Ccdc160 Ccdc160 Sult6b1 Sult6b1 Nqo2 Nqo2 LOC101831195 LOC101831195 Adh4 Adh4 LOC101843930 LOC101843930 Cndp1 Cndp1 Aadacl4fm5 Aadacl4fm5 Mgst3 Mgst3 Aadacl4fm1 Aadacl4fm1 Cyp21a1 Cyp21a1 Cyp2f2 Cyp2f2 Fdx1 Fdx1 LOC101842021 LOC101842021 Abhd14a Abhd14a LOC101823194 LOC101823194 Cndp2 Cndp2 LOC101841752 LOC101841752 Cyp26c1 Cyp26c1 ENSMAUP00000024979 ENSMAUP00000024979 LOC101831527 LOC101831527 Cyp2g1 Cyp2g1 Sult2b1 Sult2b1 Cyp4f39 Cyp4f39 Cyp2w1 Cyp2w1 LOC101829291 LOC101829291 ENSMAUP00000024468 ENSMAUP00000024468 Aldh3a1 Aldh3a1 Chac1 Chac1 Cyp2j6 Cyp2j6 Esd Esd LOC101830438 LOC101830438 Oplah Oplah LOC101830378 LOC101830378 Fmo5 Fmo5 LOC101844897 LOC101844897 Abhd14b Abhd14b LOC101823450 LOC101823450 LOC101844449 LOC101844449 LOC101826941 LOC101826941 Sult4a1 Sult4a1 Gstt1 Gstt1 Cyp7b1 Cyp7b1 Bpnt1 Bpnt1 Ugt2b1 Ugt2b1 Cyp2t4 Cyp2t4 Cyp2r1 Cyp2r1 Fmo1 Fmo1 LOC101842758 LOC101842758 Sult1b1 Sult1b1 Chac2 Chac2 Fdxr Fdxr LOC101844888 LOC101844888 Cyb5r3 Cyb5r3 Aadac Aadac Cmbl Cmbl Fmo6 Fmo6 LOC106021304 LOC106021304 Gss Gss Nnmt Nnmt LOC101840119 LOC101840119 ENSMAUP00000020668 ENSMAUP00000020668 Runx1t1 Runx1t1 Fads6 Fads6 Dpep1 Dpep1 LOC101841813 LOC101841813 Ces4a Ces4a Ahr Ahr Ahrr Ahrr Maoa Maoa Gstp1 Gstp1 Cyp2s1 Cyp2s1 Sult1d1 Sult1d1 Ncoa2 Ncoa2 ENSMAUP00000019005 ENSMAUP00000019005 Dpep3 Dpep3 Acy3 Acy3 Maob Maob Foxred2 Foxred2 ENSMAUP00000018841 ENSMAUP00000018841 Aip Aip Slc35b2 Slc35b2 Slc26a1 Slc26a1 Gstp3 Gstp3 Fdx2 Fdx2 LOC101836059 LOC101836059 Rxra Rxra LOC101838919 LOC101838919 Ncoa1 Ncoa1 Tti2 Tti2 Ptges3 Ptges3 Ggct Ggct Ptgis Ptgis Acss1 Acss1 Cbfa2t3 Cbfa2t3 LOC101844221 LOC101844221 LOC101844759 LOC101844759 LOC110341553 LOC110341553 Gstt3 Gstt3 Sult1c1 Sult1c1 Sult6b2 Sult6b2 LOC101826326 LOC101826326 Cyp2u1 Cyp2u1 Gclm Gclm Mtr Mtr Ces1d Ces1d Ces2e Ces2e Gstm1 Gstm1 Arnt2 Arnt2 Ces3 Ces3 Ggt5 Ggt5 Gstm4 Gstm4 Papss1 Papss1 Podxl2 Podxl2 Cyp39a1 Cyp39a1 Gsto2 Gsto2 Cyp19a1 Cyp19a1 Acsm4 Acsm4 Acsm2 Acsm2 Gclc Gclc Akr7a5 Akr7a5 LOC101840807 LOC101840807 Gstm2 Gstm2 Sult1c2 Sult1c2 LOC101841093 LOC101841093 LOC101826047 LOC101826047 Acsm3 Acsm3 LOC101832654 LOC101832654 Acsm1 Acsm1 Nat2 Nat2 LOC101835395 LOC101835395 LOC101822455 LOC101822455 LOC101837070 LOC101837070 Cyp2ab1 Cyp2ab1 Nat1 Nat1 Trmt112 Trmt112 Acsm5 Acsm5 Cyp46a1 Cyp46a1 LOC110342127 LOC110342127 Impad1 Impad1 Fam78b Fam78b Slc26a2 Slc26a2 Gsto1 Gsto1 Comt Comt LOC101836914 LOC101836914 Cyp24a1 Cyp24a1 LOC101840543 LOC101840543 Gm4847 Gm4847 Ggt7 Ggt7 Glyatl3 Glyatl3 Cyp1b1 Cyp1b1 Ugp2 Ugp2 Cyp1a1 Cyp1a1 Ggt1 Ggt1 LOC101823339 LOC101823339 LOC101827747 LOC101827747 LOC101838830 LOC101838830 Cyp27a1 Cyp27a1 Aoc2 Aoc2 Gstm6 Gstm6 Aipl1 Aipl1 Cyp4x1 Cyp4x1 Slc35d1 Slc35d1 Cyp4b1 Cyp4b1 Cyp7a1 Cyp7a1 LOC101831958 LOC101831958 Ces1a Ces1a LOC101841643 LOC101841643 Gstz1 Gstz1 Sult1a1 Sult1a1 Nr1h4 Nr1h4 Smox Smox Glyat Glyat Por Por Mtarc2 Mtarc2 Gstt4 Gstt4 Nr1h5 Nr1h5 Cyp4a30b Cyp4a30b ENSMAUP00000009605 ENSMAUP00000009605 Fmo9 Fmo9 Gm4952 Gm4952 Mat2a Mat2a Keg1 Keg1 Mat2b Mat2b Aldh1a1 Aldh1a1 Aoc3 Aoc3 Mtrr Mtrr Cyp3a13 Cyp3a13 Fam78a Fam78a Fmo4 Fmo4 ENSMAUP00000008408 ENSMAUP00000008408 Aldh1a7 Aldh1a7 Mgst2 Mgst2 Gsta4 Gsta4 ENSMAUP00000007993 ENSMAUP00000007993 Acy1 Acy1 LOC101840810 LOC101840810 Gstk1 Gstk1 Gstm7 Gstm7 Aldh2 Aldh2 LOC101830103 LOC101830103 Cyp4f13 Cyp4f13 Tbxas1 Tbxas1 Cyp1a2 Cyp1a2 Ces1g Ces1g Cyp4f14 Cyp4f14 LOC101841191 LOC101841191 Aldh16a1 Aldh16a1 Aadacl4fm4 Aadacl4fm4 Aadacl3 Aadacl3 LOC101823051 LOC101823051 Ccndbp1 Ccndbp1 Sult5a1 Sult5a1 Tpmt Tpmt Cyp27b1 Cyp27b1 LOC101827684 LOC101827684 Fmo2 Fmo2 Acss2 Acss2 Adh6a Adh6a Pomc Pomc N6amt1 N6amt1 Abhd10 Abhd10 Papss2 Papss2 LOC101843667 LOC101843667 Tpst2 Tpst2 LOC101844281 LOC101844281 LOC101843125 LOC101843125 Ptgs1 Ptgs1 Ahcy Ahcy ENSMAUP00000004882 ENSMAUP00000004882 LOC101832144 LOC101832144 Susd1 Susd1 Cyp2c70 Cyp2c70 Mat1a Mat1a Marc1 Marc1 CUNH1orf141 CUNH1orf141 Cyp8b1 Cyp8b1 Slc35b3 Slc35b3 Ugt1a1 Ugt1a1 LOC101843034 LOC101843034 Fmo3 Fmo3 LOC101830700 LOC101830700 Sult1e1 Sult1e1 LOC101844358 LOC101844358 Cyp26a1 Cyp26a1 Gstm3 Gstm3 ADH1 ADH1 LOC101842056 LOC101842056 Cyp4f40 Cyp4f40 Aldh1b1 Aldh1b1 Paox Paox ENSMAUP00000002290 ENSMAUP00000002290 Mgst1 Mgst1 LOC101843716 LOC101843716 Cyp26b1 Cyp26b1 Ces1e Ces1e LOC101844487 LOC101844487 Cbfa2t2 Cbfa2t2 Ugt2a3 Ugt2a3
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Adh5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (343 aa)
LOC101825889Cytochrome P450 2A8; Highly active in 7-ethoxycoumarin O-deethylation, and benzphetamine N-demethylation; moderately active in testosterone 7- alpha-hydroxylation, ethylmorphine N-demethylation, p-nitroanisole O- demethylation; and only slightly active in benzopyrene 3-hydroxylation, 7-ethoxyresorufin O-deethylation, testosterone 2-alpha-hydroxylation and testosterone 17-oxidation. Competent in the metabolic activation of aflatoxin B1; Belongs to the cytochrome P450 family. (494 aa)
Ces2hCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (558 aa)
Cbr3Carbonyl reductase [NADPH] 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
InmtIndolethylamine N-methyltransferase. (262 aa)
Ces5aCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (78 aa)
HpgdsHematopoietic prostaglandin D synthase isoform X2; Belongs to the GST superfamily. (199 aa)
LOC101822730Glutathione S-transferase A6; Belongs to the GST superfamily. (196 aa)
LOC101822554UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
LOC101831088Cytochrome P450 2C26; Catalyzes the hydroxylation of tolbutamide and the N- demethylation of aminopyrine and benzphetamine. (490 aa)
BphlValacyclovir hydrolase. (291 aa)
LOC101833813Cytochrome P450 2B1-like. (456 aa)
Ccdc160Coiled-coil domain-containing protein 160 isoform X2. (323 aa)
Sult6b1Sulfotransferase; Belongs to the sulfotransferase 1 family. (303 aa)
Nqo2Ribosyldihydronicotinamide dehydrogenase [quinone]. (231 aa)
LOC101831195Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa)
Adh4Alcohol dehydrogenase 4. (377 aa)
LOC101843930UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa)
Cndp1beta-Ala-His dipeptidase. (514 aa)
Aadacl4fm5Arylacetamide deacetylase-like 4 isoform X1. (387 aa)
Mgst3Microsomal glutathione S-transferase 3. (152 aa)
Aadacl4fm1Arylacetamide deacetylase-like 4. (388 aa)
Cyp21a1Steroid 21-hydroxylase isoform X2; Belongs to the cytochrome P450 family. (496 aa)
Cyp2f2Cytochrome P450 2F2; Belongs to the cytochrome P450 family. (491 aa)
Fdx1Adrenodoxin, mitochondrial. (188 aa)
LOC101842021Cytochrome P450 2C26-like; Belongs to the cytochrome P450 family. (217 aa)
Abhd14aProtein ABHD14A. (261 aa)
LOC101823194Cytochrome P450 4A12; Belongs to the cytochrome P450 family. (508 aa)
Cndp2Cytosolic non-specific dipeptidase. (475 aa)
LOC101841752Cytochrome P450 2C27-like. (401 aa)
Cyp26c1Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (516 aa)
ENSMAUP00000024979annotation not available (426 aa)
LOC101831527Cytochrome P450 2C19-like; Belongs to the cytochrome P450 family. (490 aa)
Cyp2g1Cytochrome P450 2G1 isoform X1; Belongs to the cytochrome P450 family. (494 aa)
Sult2b1Sulfotransferase; Belongs to the sulfotransferase 1 family. (371 aa)
Cyp4f39Cytochrome P450 4F22; Belongs to the cytochrome P450 family. (532 aa)
Cyp2w1Cytochrome P450 2W1; Belongs to the cytochrome P450 family. (493 aa)
LOC101829291Cytochrome P450 4F5-like; Belongs to the cytochrome P450 family. (524 aa)
ENSMAUP00000024468annotation not available (458 aa)
Aldh3a1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (454 aa)
Chac1Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (251 aa)
Cyp2j6Cytochrome P450 2J6-like; Belongs to the cytochrome P450 family. (421 aa)
EsdS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
LOC101830438Cytochrome P450 2J3-like isoform X1; Belongs to the cytochrome P450 family. (502 aa)
Oplah5-oxoprolinase. (53 aa)
LOC101830378Cytochrome P450 2C26-like isoform X2; Belongs to the cytochrome P450 family. (490 aa)
Fmo5Flavin containing dimethylaniline monoxygenase 5. (368 aa)
LOC101844897UDP-glucuronosyltransferase 2B4-like. (462 aa)
Abhd14bProtein ABHD14B. (210 aa)
LOC101823450Cytochrome P450 2C25-like. (383 aa)
LOC101844449UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (288 aa)
LOC101826941Cytochrome P450 2A3-like; Belongs to the cytochrome P450 family. (494 aa)
Sult4a1Sulfotransferase; Belongs to the sulfotransferase 1 family. (267 aa)
Gstt1Glutathione S-transferase theta-1 isoform X4; Belongs to the GST superfamily. (240 aa)
Cyp7b125-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (509 aa)
Bpnt13'(2'),5'-bisphosphate nucleotidase 1 isoform X2. (291 aa)
Ugt2b1UDP-glucuronosyltransferase 2B1; Belongs to the UDP-glycosyltransferase family. (530 aa)
Cyp2t4LOW QUALITY PROTEIN: cytochrome P450 2F3-like. (478 aa)
Cyp2r1Vitamin D 25-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
Fmo1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
LOC101842758Cytochrome P450 4V2; Belongs to the cytochrome P450 family. (522 aa)
Sult1b1Sulfotransferase; Belongs to the sulfotransferase 1 family. (303 aa)
Chac2Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (178 aa)
FdxrNADPH:adrenodoxin oxidoreductase, mitochondrial. (493 aa)
LOC101844888Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (499 aa)
Cyb5r3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (342 aa)
AadacArylacetamide deacetylase. (397 aa)
CmblCarboxymethylenebutenolidase homolog. (245 aa)
Fmo6Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
LOC106021304Cytochrome P450 4A10-like. (368 aa)
GssGlutathione synthetase. (463 aa)
NnmtNicotinamide N-methyltransferase isoform X1. (264 aa)
LOC101840119Liver carboxylesterase-like. (506 aa)
ENSMAUP00000020668annotation not available (284 aa)
Runx1t1Protein CBFA2T1 isoform X1. (604 aa)
Fads6Fatty acid desaturase 6. (342 aa)
Dpep1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
LOC101841813Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (561 aa)
Ces4aCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (564 aa)
AhrAryl hydrocarbon receptor. (731 aa)
AhrrAryl hydrocarbon receptor repressor. (702 aa)
MaoaAmine oxidase. (525 aa)
Gstp1Glutathione S-transferase P; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity); Belongs to the GST superfamily. Pi family. (210 aa)
Cyp2s1Cytochrome P450 2S1 isoform X1; Belongs to the cytochrome P450 family. (500 aa)
Sult1d1Sulfotransferase; Belongs to the sulfotransferase 1 family. (225 aa)
Ncoa2Nuclear receptor coactivator. (1475 aa)
ENSMAUP00000019005annotation not available (354 aa)
Dpep3Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (345 aa)
Acy3N-acyl-aromatic-L-amino acid amidohydrolase (Carboxylate-forming). (319 aa)
MaobAmine oxidase. (522 aa)
Foxred2FAD-dependent oxidoreductase domain-containing protein 2. (666 aa)
ENSMAUP00000018841annotation not available (120 aa)
AipAH receptor-interacting protein. (330 aa)
Slc35b2Adenosine 3'-phospho 5'-phosphosulfate transporter 1 isoform X1. (431 aa)
Slc26a1Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (698 aa)
Gstp3Glutathione S-transferase P 2-like; Belongs to the GST superfamily. (197 aa)
Fdx2Ferredoxin-2, mitochondrial. (175 aa)
LOC101836059Aflatoxin B1 aldehyde reductase member 3. (327 aa)
RxraRetinoic acid receptor RXR-alpha. (457 aa)
LOC101838919Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (120 aa)
Ncoa1Nuclear receptor coactivator. (1444 aa)
Tti2TELO2-interacting protein 2. (516 aa)
Ptges3Prostaglandin E synthase 3. (160 aa)
GgctGamma-glutamylcyclotransferase isoform X1. (190 aa)
PtgisProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (493 aa)
Acss1Acetyl-coenzyme A synthetase. (681 aa)
Cbfa2t3Protein CBFA2T3 isoform X2. (619 aa)
LOC101844221Cytochrome P450 2B1-like; Belongs to the cytochrome P450 family. (491 aa)
LOC101844759Cytochrome P450 2B1-like; Belongs to the cytochrome P450 family. (491 aa)
LOC110341553Glutathione S-transferase alpha-1-like. (115 aa)
Gstt3Glutathione S-transferase theta-3; Belongs to the GST superfamily. (241 aa)
Sult1c1Sulfotransferase; Belongs to the sulfotransferase 1 family. (304 aa)
Sult6b2Sulfotransferase; Belongs to the sulfotransferase 1 family. (286 aa)
LOC101826326Cytochrome P450 2A9; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (493 aa)
Cyp2u1Cytochrome P450 2U1; Belongs to the cytochrome P450 family. (532 aa)
GclmGlutamate--cysteine ligase regulatory subunit. (153 aa)
MtrMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1253 aa)
Ces1dCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
Ces2ePyrethroid hydrolase Ces2e-like. (502 aa)
Gstm1Glutathione S-transferase. (227 aa)
Arnt2Aryl hydrocarbon receptor nuclear translocator 2 isoform X1. (712 aa)
Ces3Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (570 aa)
Ggt5Gamma-glutamyltransferase 5 isoform X1. (570 aa)
Gstm4Glutathione S-transferase Mu 1. (218 aa)
Papss1Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 isoform X2. (624 aa)
Podxl2Podocalyxin-like protein 2. (599 aa)
Cyp39a124-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (377 aa)
Gsto2Glutathione S-transferase omega-2 isoform X1; Belongs to the GST superfamily. (248 aa)
Cyp19a1Aromatase; Belongs to the cytochrome P450 family. (503 aa)
Acsm4Acyl-coenzyme A synthetase ACSM4, mitochondrial. (580 aa)
Acsm2Acyl-coenzyme A synthetase ACSM2, mitochondrial. (577 aa)
GclcGlutamate--cysteine ligase catalytic subunit isoform X1. (637 aa)
Akr7a5Aflatoxin B1 aldehyde reductase member 2. (367 aa)
LOC101840807Glutathione S-transferase alpha-5-like. (132 aa)
Gstm2Glutathione S-transferase; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. (218 aa)
Sult1c2Sulfotransferase; Belongs to the sulfotransferase 1 family. (299 aa)
LOC101841093Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa)
LOC101826047Lanosterol 14-alpha demethylase; Belongs to the cytochrome P450 family. (200 aa)
Acsm3Acyl-coenzyme A synthetase ACSM3, mitochondrial isoform X2. (622 aa)
LOC101832654Carboxylesterase 1C-like. (426 aa)
Acsm1Acyl-coenzyme A synthetase ACSM1, mitochondrial. (577 aa)
Nat2Arylamine N-acetyltransferase 2; Participates in the detoxification of a plethora of hydrazine and arylamine drugs. (290 aa)
LOC101835395Aldehyde dehydrogenase, cytosolic 1. (236 aa)
LOC101822455Glutathione S-transferase A6. (212 aa)
LOC101837070Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (294 aa)
Cyp2ab1Cytochrome P450 2J2-like; Belongs to the cytochrome P450 family. (280 aa)
Nat1Arylamine N-acetyltransferase 1; Participates in the detoxification of a plethora of hydrazine and arylamine drugs. (290 aa)
Trmt112Multifunctional methyltransferase subunit TRM112-like protein. (125 aa)
Acsm5Acyl-coenzyme A synthetase ACSM5, mitochondrial. (578 aa)
Cyp46a1Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (500 aa)
LOC110342127LOW QUALITY PROTEIN: glutathione S-transferase Mu 3-like; Belongs to the GST superfamily. (217 aa)
Impad1Inositol monophosphatase 3. (357 aa)
Fam78bProtein FAM78B. (261 aa)
Slc26a2Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (732 aa)
Gsto1Glutathione S-transferase omega-1-like isoform X1; Belongs to the GST superfamily. (240 aa)
ComtCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (264 aa)
LOC101836914Cytochrome P450 3A31; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (473 aa)
Cyp24a11,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa)
LOC101840543Glutathione S-transferase. (206 aa)
Gm4847Dimethylaniline monooxygenase [N-oxide-forming]. (538 aa)
Ggt7Gamma-glutamyltransferase 7. (185 aa)
Glyatl3Glycine N-acyltransferase-like protein 3 isoform X1. (290 aa)
Cyp1b1Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (541 aa)
Ugp2UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
Cyp1a1Cytochrome P450 1A1; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy [...] (507 aa)
Ggt1Gamma-glutamyltranspeptidase 1. (568 aa)
LOC101823339Cytochrome P450 11B1, mitochondrial; A cytochrome P450 monooxygenase involved in the biosynthesis of adrenal corticoids. Catalyzes the hydroxylation of carbon hydrogen bond at 11-beta position of 11-deoxycortisol and 11- deoxycorticosterone/21-hydroxyprogesterone yielding cortisol or corticosterone, respectively. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) [...] (319 aa)
LOC101827747Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
LOC101838830LOW QUALITY PROTEIN: cytochrome P450 2D20-like; Belongs to the cytochrome P450 family. (476 aa)
Cyp27a1Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (534 aa)
Aoc2Amine oxidase. (757 aa)
Gstm6Glutathione S-transferase. (218 aa)
Aipl1Aryl-hydrocarbon-interacting protein-like 1. (328 aa)
Cyp4x1Cytochrome P450 4X1; Belongs to the cytochrome P450 family. (505 aa)
Slc35d1UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter. (287 aa)
Cyp4b1Cytochrome P450 4B1; Belongs to the cytochrome P450 family. (509 aa)
Cyp7a1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
LOC101831958Lithocholate 6-beta-hydroxylase; Catalyzes the 6 beta-hydroxylation of lithocholic acid and steroid hormones; Belongs to the cytochrome P450 family. (503 aa)
Ces1aCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (563 aa)
LOC101841643Arylacetamide deacetylase-like 4. (406 aa)
Gstz1Maleylacetoacetate isomerase isoform X1; Belongs to the GST superfamily. (223 aa)
Sult1a1Sulfotransferase; Belongs to the sulfotransferase 1 family. (250 aa)
Nr1h4Farnesoid-X-receptor beta splice variant 2. (487 aa)
SmoxSpermine oxidase isoform X3. (585 aa)
GlyatGlycine N-acyltransferase-like. (296 aa)
PorNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (672 aa)
Mtarc2Mitochondrial amidoxime reducing component 2. (338 aa)
Gstt4Glutathione S-transferase theta-4; Belongs to the GST superfamily. (240 aa)
Nr1h5Bile acid receptor-like. (361 aa)
Cyp4a30bCytochrome P450 4A14-like; Belongs to the cytochrome P450 family. (477 aa)
ENSMAUP00000009605annotation not available (414 aa)
Fmo9Flavin-containing monooxygenase. (539 aa)
Gm4952Glycine N-acyltransferase-like protein. (296 aa)
Mat2aS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
Keg1Glycine N-acyltransferase-like protein Keg1 isoform X2. (294 aa)
Mat2bMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (334 aa)
Aldh1a1Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity). (513 aa)
Aoc3Amine oxidase. (763 aa)
MtrrMethionine synthase reductase. (697 aa)
Cyp3a13Cytochrome P450 3A9. (503 aa)
Fam78aProtein FAM78A. (283 aa)
Fmo4Dimethylaniline monooxygenase [N-oxide-forming]. (557 aa)
ENSMAUP00000008408annotation not available (106 aa)
Aldh1a7Aldehyde dehydrogenase, cytosolic 1-like; Belongs to the aldehyde dehydrogenase family. (442 aa)
Mgst2Microsomal glutathione S-transferase 2. (146 aa)
Gsta4Glutathione S-transferase alpha-4; Belongs to the GST superfamily. (222 aa)
ENSMAUP00000007993annotation not available (126 aa)
Acy1Aminoacylase-1. (408 aa)
LOC101840810Sulfotransferase; Belongs to the sulfotransferase 1 family. (292 aa)
Gstk1Glutathione S-transferase kappa. (226 aa)
Gstm7Glutathione S-transferase. (218 aa)
Aldh2Aldehyde dehydrogenase, mitochondrial; Belongs to the aldehyde dehydrogenase family. (519 aa)
LOC101830103Cytochrome P450 4F5 isoform X1; Belongs to the cytochrome P450 family. (524 aa)
Cyp4f13Cytochrome P450 4F6 isoform X1; Belongs to the cytochrome P450 family. (524 aa)
Tbxas1thromboxane-A synthase. (428 aa)
Cyp1a2Cytochrome P450 1A2; A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E [...] (513 aa)
Ces1gCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
Cyp4f14leukotriene-B4 omega-hydroxylase 3 isoform X2; Belongs to the cytochrome P450 family. (524 aa)
LOC101841191Cytochrome P450 2J3-like. (443 aa)
Aldh16a1Aldehyde dehydrogenase family 16 member A1. (802 aa)
Aadacl4fm4AADACL4 family member 4. (334 aa)
Aadacl3Arylacetamide deacetylase-like 3. (408 aa)
LOC101823051Alcohol dehydrogenase 1 isoform X2. (362 aa)
Ccndbp1cyclin-D1-binding protein 1. (305 aa)
Sult5a1Sulfotransferase; Belongs to the sulfotransferase 1 family. (291 aa)
TpmtThiopurine S-methyltransferase. (224 aa)
Cyp27b125-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (508 aa)
LOC101827684Glutathione S-transferase Mu 2-like; Belongs to the GST superfamily. (218 aa)
Fmo2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
Acss2Acetyl-coenzyme A synthetase, cytoplasmic. (657 aa)
Adh6aAlcohol dehydrogenase 1-like. (375 aa)
PomcPro-opiomelanocortin. (234 aa)
N6amt1hemK methyltransferase family member 2. (197 aa)
Abhd10Mycophenolic acid acyl-glucuronide esterase, mitochondrial. (297 aa)
Papss2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform X2. (567 aa)
LOC101843667UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa)
Tpst2Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (390 aa)
LOC101844281Cytochrome P450 20A1. (216 aa)
LOC101843125UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (389 aa)
Ptgs1Prostaglandin G/H synthase 1. (607 aa)
AhcyAdenosylhomocysteinase. (432 aa)
ENSMAUP00000004882annotation not available (294 aa)
LOC101832144Cytochrome P450 2C28; Catalyzes the N-demethylation of aminopyrine and benzphetamine, but does not catalyze the hydroxylation of tolbutamide, testosterone, and progesterone; Belongs to the cytochrome P450 family. (490 aa)
Susd1Sushi domain-containing protein 1. (757 aa)
Cyp2c70Cytochrome P450 2C70-like; Belongs to the cytochrome P450 family. (489 aa)
Mat1aS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
Marc1Mitochondrial amidoxime-reducing component 1. (295 aa)
CUNH1orf141Uncharacterized protein C1orf141 homolog. (390 aa)
Cyp8b17-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (501 aa)
Slc35b3Adenosine 3'-phospho 5'-phosphosulfate transporter 2. (348 aa)
Ugt1a1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (535 aa)
LOC101843034UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
Fmo3Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
LOC101830700Cytochrome P450 2J3 isoform X1; Belongs to the cytochrome P450 family. (502 aa)
Sult1e1Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
LOC101844358Liver carboxylesterase; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. (560 aa)
Cyp26a1Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (497 aa)
Gstm3Glutathione S-transferase. (226 aa)
ADH1Alcohol dehydrogenase 1. (361 aa)
LOC101842056UDP-glucuronosyltransferase 2A2; Belongs to the UDP-glycosyltransferase family. (692 aa)
Cyp4f40Cytochrome P450 4F4-like; Belongs to the cytochrome P450 family. (532 aa)
Aldh1b1Aldehyde dehydrogenase X, mitochondrial; Belongs to the aldehyde dehydrogenase family. (519 aa)
PaoxPeroxisomal N(1)-acetyl-spermine/spermidine oxidase. (503 aa)
ENSMAUP00000002290annotation not available (209 aa)
Mgst1Microsomal glutathione S-transferase 1. (129 aa)
LOC101843716Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (493 aa)
Cyp26b1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa)
Ces1eCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
LOC101844487Cytochrome P450, family 2 subfamily B polypeptide 29; Belongs to the cytochrome P450 family. (491 aa)
Cbfa2t2Protein CBFA2T2 isoform X3. (594 aa)
Ugt2a3UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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