STRINGSTRING
Rps27a Rps27a Smad2 Smad2 Ldlrad4 Ldlrad4 Tgfb1 Tgfb1 Kxd1 Kxd1 Tgfbr2 Tgfbr2 ENSMAUP00000002256 ENSMAUP00000002256 Pmepa1 Pmepa1 ENSMAUP00000007258 ENSMAUP00000007258 Tgfbr1 Tgfbr1 Strap Strap ENSMAUP00000019431 ENSMAUP00000019431 Ppp1r15a Ppp1r15a ENSMAUP00000022314 ENSMAUP00000022314 Smad7 Smad7 ENSMAUP00000008197 ENSMAUP00000008197 Stub1 Stub1 Smad3 Smad3 Bambi Bambi LOC101823019 LOC101823019 Smurf2 Smurf2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Ldlrad4Low-density lipoprotein receptor class A domain-containing protein 4 isoform X1. (306 aa)
Tgfb1Transforming growth factor beta-1. (286 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ENSMAUP00000002256annotation not available (75 aa)
Pmepa1Protein TMEPAI. (275 aa)
ENSMAUP00000007258annotation not available (117 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
StrapSerine-threonine kinase receptor-associated protein. (350 aa)
ENSMAUP00000019431annotation not available (150 aa)
Ppp1r15aProtein phosphatase 1 regulatory subunit 15A. (611 aa)
ENSMAUP00000022314annotation not available (101 aa)
Smad7Mothers against decapentaplegic homolog. (427 aa)
ENSMAUP00000008197annotation not available (303 aa)
Stub1E3 ubiquitin-protein ligase CHIP isoform X1. (303 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
BambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
LOC101823019Ubiquitin-like. (114 aa)
Smurf2E3 ubiquitin-protein ligase. (67 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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