STRINGSTRING
Bambi Bambi Smad3 Smad3 Cbl Cbl ENSMAUP00000023933 ENSMAUP00000023933 Furin Furin Stub1 Stub1 ENSMAUP00000022314 ENSMAUP00000022314 Nedd8 Nedd8 Ppp1r15a Ppp1r15a ENSMAUP00000019431 ENSMAUP00000019431 Fkbp1a-2 Fkbp1a-2 Itga8 Itga8 ENSMAUP00000017845 ENSMAUP00000017845 Strap Strap Ltbp2 Ltbp2 Itgav Itgav Itgb3 Itgb3 Ltbp3 Ltbp3 Itgb6 Itgb6 Tgfbr1 Tgfbr1 Itgb5 Itgb5 Ltbp4 Ltbp4 Smad7 Smad7 Ube2m Ube2m Ltbp1 Ltbp1 Smurf2 Smurf2 Tgfb2 Tgfb2 ENSMAUP00000008427 ENSMAUP00000008427 Smad4 Smad4 ENSMAUP00000008197 ENSMAUP00000008197 ENSMAUP00000007258 ENSMAUP00000007258 Pcsk4 Pcsk4 Fbn1 Fbn1 Tgfbr2 Tgfbr2 LOC101823019 LOC101823019 Rps27a Rps27a Smad2 Smad2 Itgb8 Itgb8 Itgb1 Itgb1 Pmepa1 Pmepa1 Zfyve9 Zfyve9 ENSMAUP00000002256 ENSMAUP00000002256 Tgfb3 Tgfb3 Ldlrad4 Ldlrad4 Tgfb1 Tgfb1 Kxd1 Kxd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
Smad3Mothers against decapentaplegic homolog. (425 aa)
CblE3 ubiquitin-protein ligase CBL. (51 aa)
ENSMAUP00000023933annotation not available (228 aa)
FurinFurin; Belongs to the peptidase S8 family. (794 aa)
Stub1E3 ubiquitin-protein ligase CHIP isoform X1. (303 aa)
ENSMAUP00000022314annotation not available (101 aa)
Nedd8NEDD8. (81 aa)
Ppp1r15aProtein phosphatase 1 regulatory subunit 15A. (611 aa)
ENSMAUP00000019431annotation not available (150 aa)
Fkbp1a-2Peptidylprolyl isomerase. (108 aa)
Itga8Integrin alpha-8; Belongs to the integrin alpha chain family. (945 aa)
ENSMAUP00000017845annotation not available (104 aa)
StrapSerine-threonine kinase receptor-associated protein. (350 aa)
Ltbp2Latent-transforming growth factor beta-binding protein 2 isoform X1. (1815 aa)
ItgavIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1045 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (787 aa)
Ltbp3Latent-transforming growth factor beta-binding protein 3 isoform X2. (1253 aa)
Itgb6Integrin beta; Belongs to the integrin beta chain family. (759 aa)
Tgfbr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
Itgb5Integrin beta 5. (579 aa)
Ltbp4Latent-transforming growth factor beta-binding protein 4. (1108 aa)
Smad7Mothers against decapentaplegic homolog. (427 aa)
Ube2mNEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
Ltbp1Latent-transforming growth factor beta-binding protein 1 isoform X8. (1386 aa)
Smurf2E3 ubiquitin-protein ligase. (67 aa)
Tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ENSMAUP00000008427annotation not available (193 aa)
Smad4Mothers against decapentaplegic homolog. (552 aa)
ENSMAUP00000008197annotation not available (303 aa)
ENSMAUP00000007258annotation not available (117 aa)
Pcsk4LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (639 aa)
Fbn1Fibrillin-1 isoform X1. (2871 aa)
Tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC101823019Ubiquitin-like. (114 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Smad2Mothers against decapentaplegic homolog. (467 aa)
Itgb8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (92 aa)
Pmepa1Protein TMEPAI. (275 aa)
Zfyve9Zinc finger FYVE domain-containing protein. (1378 aa)
ENSMAUP00000002256annotation not available (75 aa)
Tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
Ldlrad4Low-density lipoprotein receptor class A domain-containing protein 4 isoform X1. (306 aa)
Tgfb1Transforming growth factor beta-1. (286 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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