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Pak1 Pak1 Vav2 Vav2 Vav3 Vav3 Grap2 Grap2 Igll5 Igll5 LOC101842094 LOC101842094 Plcg2 Plcg2 Map3k1 Map3k1 ENSMAUP00000005400 ENSMAUP00000005400 Jun Jun Mapk8 Mapk8 ENSMAUP00000004122 ENSMAUP00000004122 Lyn Lyn Eras Eras Map2k7 Map2k7 Spns3 Spns3 Plcg1 Plcg1 LOC101832879 LOC101832879 Sos1 Sos1 Clnk Clnk Nradd Nradd Map2k4 Map2k4 Pak2 Pak2 Vav1 Vav1 ENSMAUP00000024144 ENSMAUP00000024144 Hras Hras Nras Nras Shc1 Shc1 Fos Fos Syk Syk ENSMAUP00000021198 ENSMAUP00000021198 Fcrls Fcrls Lcp2 Lcp2 Rac1 Rac1 Kras Kras Mapk9 Mapk9 ENSMAUP00000018578 ENSMAUP00000018578 Mapk1 Mapk1 ENSMAUP00000018538 ENSMAUP00000018538 Mapk10 Mapk10 Grb2 Grb2 Igkv7-33 Igkv7-33 ENSMAUP00000017584 ENSMAUP00000017584 Fcer1a Fcer1a ENSMAUP00000017391 ENSMAUP00000017391 Ms4a2 Ms4a2 Ms4a8a Ms4a8a ENSMAUP00000010832 ENSMAUP00000010832 Spns1 Spns1 Ms4a12 Ms4a12 Ms4a1 Ms4a1 Lat Lat Mapk3 Mapk3 Harbi1 Harbi1 Ms4a15 Ms4a15 Ms4a10 Ms4a10 Csde1 Csde1 ENSMAUP00000014774 ENSMAUP00000014774 Fcrl5 Fcrl5 Fcer1g Fcer1g Fosl2 Fosl2 Ms4a4a Ms4a4a LOC110340582 LOC110340582
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pak1P21 (RAC1) activated kinase 1. (490 aa)
Vav2Guanine nucleotide exchange factor VAV2 isoform X2. (868 aa)
Vav3Guanine nucleotide exchange factor VAV3 isoform X1. (847 aa)
Grap2GRB2-related adapter protein 2 isoform X1. (324 aa)
Igll5Immunoglobulin lambda-like polypeptide 5. (209 aa)
LOC101842094Fc receptor-like protein 1. (346 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1. (1475 aa)
ENSMAUP00000005400annotation not available (141 aa)
JunTranscription factor AP-1; Belongs to the bZIP family. (338 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
ENSMAUP00000004122annotation not available (116 aa)
LynTyrosine-protein kinase. (438 aa)
ErasGTPase ERas. (228 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (520 aa)
Spns3Protein spinster homolog 3 isoform X1. (519 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1293 aa)
LOC101832879Ankyrin repeat and KH domain-containing protein 1 isoform X4. (2527 aa)
Sos1Son of sevenless homolog 1. (1319 aa)
ClnkCytokine-dependent hematopoietic cell linker. (427 aa)
NraddDeath domain-containing membrane protein NRADD-like isoform X1. (229 aa)
Map2k4Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily. (131 aa)
Pak2Non-specific serine/threonine protein kinase. (501 aa)
Vav1Proto-oncogene vav. (845 aa)
ENSMAUP00000024144annotation not available (159 aa)
HrasGTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
NrasNRAS proto-oncogene, GTPase. (98 aa)
Shc1SHC-transforming protein 1 isoform X1. (579 aa)
FosProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
SykTyrosine-protein kinase. (629 aa)
ENSMAUP00000021198annotation not available (119 aa)
FcrlsFc receptor-like protein 2. (502 aa)
Lcp2Lymphocyte cytosolic protein 2. (542 aa)
Rac1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
KrasGTPase KRas isoform X3. (189 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
ENSMAUP00000018578annotation not available (119 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
ENSMAUP00000018538annotation not available (171 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Igkv7-33Immunoglobulin kappa chain variable 7-33. (144 aa)
ENSMAUP00000017584annotation not available (109 aa)
Fcer1aHigh affinity immunoglobulin epsilon receptor subunit alpha. (239 aa)
ENSMAUP00000017391annotation not available (112 aa)
Ms4a2Membrane spanning 4-domains A2. (127 aa)
Ms4a8aMembrane-spanning 4-domains subfamily A member 8. (263 aa)
ENSMAUP00000010832annotation not available (74 aa)
Spns1Protein spinster homolog 1. (528 aa)
Ms4a12Membrane-spanning 4-domains subfamily A member 12. (269 aa)
Ms4a1B-lymphocyte antigen CD20 isoform X1. (298 aa)
LatLinker for activation of T-cells family member 1 isoform X1. (241 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Harbi1Putative nuclease HARBI1. (349 aa)
Ms4a15Membrane-spanning 4-domains subfamily A member 15. (245 aa)
Ms4a10Membrane-spanning 4-domains subfamily A member 10. (100 aa)
Csde1Cold shock domain-containing protein E1 isoform X3. (798 aa)
ENSMAUP00000014774annotation not available (123 aa)
Fcrl5Fc receptor-like protein 5 isoform X1. (588 aa)
Fcer1gHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
Fosl2Fos-related antigen 2. (324 aa)
Ms4a4aMembrane-spanning 4-domains subfamily A member 4A-like isoform X1. (236 aa)
LOC110340582Uncharacterized protein LOC110340582. (143 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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