STRINGSTRING
Rps6ka2 Rps6ka2 ENSMAUP00000001261 ENSMAUP00000001261 Dusp6 Dusp6 Fos Fos ENSMAUP00000021418 ENSMAUP00000021418 Ppp2cb Ppp2cb Ppp4r4 Ppp4r4 Atf2 Atf2 Dusp4 Dusp4 Creb1 Creb1 Rps6ka1 Rps6ka1 Mapk9 Mapk9 Mapk1 Mapk1 Mapk10 Mapk10 ENSMAUP00000017825 ENSMAUP00000017825 Mapk14 Mapk14 Fosl2 Fosl2 Relch Relch Mapk15 Mapk15 Rps6ka3 Rps6ka3 Vrk3 Vrk3 Rps6ka5 Rps6ka5 Ppp4r1 Ppp4r1 Ppp2r1a Ppp2r1a Atf1 Atf1 Dusp3 Dusp3 Atf7 Atf7 Dusp7 Dusp7 Ppp2r1b Ppp2r1b Mapk11 Mapk11 Mapk7 Mapk7 Elk1 Elk1 Mapk3 Mapk3 Ppp2r5d Ppp2r5d Ppp2ca Ppp2ca Creb5 Creb5 Jun Jun Mapk8 Mapk8 Mapkapk2 Mapkapk2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rps6ka2Ribosomal protein S6 kinase. (733 aa)
ENSMAUP00000001261annotation not available (61 aa)
Dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (379 aa)
FosProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
ENSMAUP00000021418annotation not available (290 aa)
Ppp2cbProtein phosphatase 2 catalytic subunit beta. (299 aa)
Ppp4r4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (875 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa)
Dusp4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Rps6ka1Ribosomal protein S6 kinase. (743 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
ENSMAUP00000017825annotation not available (97 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Fosl2Fos-related antigen 2. (324 aa)
RelchlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X2. (1211 aa)
Mapk15Mitogen-activated protein kinase. (539 aa)
Rps6ka3Ribosomal protein S6 kinase. (740 aa)
Vrk3Inactive serine/threonine-protein kinase VRK3 isoform X1. (450 aa)
Rps6ka5Ribosomal protein S6 kinase. (849 aa)
Ppp4r1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (573 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
Atf1Cyclic AMP-dependent transcription factor ATF-1 isoform X3. (269 aa)
Dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (210 aa)
Atf7Cyclic AMP-dependent transcription factor ATF-7. (385 aa)
Dusp7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
Ppp2r1bSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (693 aa)
Mapk11Mitogen-activated protein kinase. (355 aa)
Mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa)
Elk1ETS domain-containing protein Elk-1. (426 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Ppp2r5dSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa)
Ppp2caSerine/threonine-protein phosphatase. (309 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X3. (508 aa)
JunTranscription factor AP-1; Belongs to the bZIP family. (338 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Mapkapk2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (386 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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