STRINGSTRING
Irak1 Irak1 Kxd1 Kxd1 Ppp4r1 Ppp4r1 Map2k7 Map2k7 Ppp2r1a Ppp2r1a Ube2n Ube2n Nod2 Nod2 Mapkapk3 Mapkapk3 Mapkapk2 Mapkapk2 Traf6 Traf6 Mapk8 Mapk8 Jun Jun Rps27a Rps27a LOC101823019 LOC101823019 Ikbkg Ikbkg Creb5 Creb5 Ripk2 Ripk2 ENSMAUP00000007258 ENSMAUP00000007258 Ppp2ca Ppp2ca Ppp2r5d Ppp2r5d Tab2 Tab2 Mapk3 Mapk3 Elk1 Elk1 Mapk7 Mapk7 ENSMAUP00000012929 ENSMAUP00000012929 Rps6ka5 Rps6ka5 Vrk3 Vrk3 Rps6ka3 Rps6ka3 Mapk15 Mapk15 Relch Relch Fosl2 Fosl2 Mapk14 Mapk14 ENSMAUP00000017825 ENSMAUP00000017825 Map3k7 Map3k7 Mapk10 Mapk10 Mapk1 Mapk1 Mapk9 Mapk9 ENSMAUP00000019431 ENSMAUP00000019431 Rps6ka1 Rps6ka1 Nfkb1 Nfkb1 Creb1 Creb1 Dusp4 Dusp4 Atf2 Atf2 Ppp4r4 Ppp4r4 Ppp2cb Ppp2cb ENSMAUP00000021418 ENSMAUP00000021418 Fos Fos Atf1 Atf1 ENSMAUP00000022314 ENSMAUP00000022314 Dusp3 Dusp3 Atf7 Atf7 Map2k3 Map2k3 Dusp7 Dusp7 Ube2v1 Ube2v1 Map2k6 Map2k6 Map3k20 Map3k20 Map2k4 Map2k4 Tab1 Tab1 Ppp2r1b Ppp2r1b Mapk11 Mapk11 Nod1 Nod1 Tab3 Tab3 Dusp6 Dusp6 ENSMAUP00000001261 ENSMAUP00000001261 ENSMAUP00000002256 ENSMAUP00000002256 Rps6ka2 Rps6ka2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Irak1Interleukin-1 receptor-associated kinase 1 isoform X2. (747 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Ppp4r1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (573 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (520 aa)
Ppp2r1aSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
Ube2nUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
Nod2Nucleotide-binding oligomerization domain-containing protein 2 isoform X2. (1023 aa)
Mapkapk3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
Mapkapk2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (386 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
JunTranscription factor AP-1; Belongs to the bZIP family. (338 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC101823019Ubiquitin-like. (114 aa)
IkbkgNF-kappa-B essential modulator isoform X1. (412 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X3. (508 aa)
Ripk2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (325 aa)
ENSMAUP00000007258annotation not available (117 aa)
Ppp2caSerine/threonine-protein phosphatase. (309 aa)
Ppp2r5dSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (594 aa)
Tab2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Elk1ETS domain-containing protein Elk-1. (426 aa)
Mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa)
ENSMAUP00000012929annotation not available (90 aa)
Rps6ka5Ribosomal protein S6 kinase. (849 aa)
Vrk3Inactive serine/threonine-protein kinase VRK3 isoform X1. (450 aa)
Rps6ka3Ribosomal protein S6 kinase. (740 aa)
Mapk15Mitogen-activated protein kinase. (539 aa)
RelchlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X2. (1211 aa)
Fosl2Fos-related antigen 2. (324 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
ENSMAUP00000017825annotation not available (97 aa)
Map3k7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (497 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
ENSMAUP00000019431annotation not available (150 aa)
Rps6ka1Ribosomal protein S6 kinase. (743 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Dusp4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa)
Ppp4r4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1. (875 aa)
Ppp2cbProtein phosphatase 2 catalytic subunit beta. (299 aa)
ENSMAUP00000021418annotation not available (290 aa)
FosProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
Atf1Cyclic AMP-dependent transcription factor ATF-1 isoform X3. (269 aa)
ENSMAUP00000022314annotation not available (101 aa)
Dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (210 aa)
Atf7Cyclic AMP-dependent transcription factor ATF-7. (385 aa)
Map2k3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
Dusp7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
Ube2v1LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 variant 1-like. (121 aa)
Map2k6Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa)
Map3k20Mitogen-activated protein kinase kinase kinase 20. (762 aa)
Map2k4Dual specificity mitogen-activated protein kinase kinase 4 isoform X2; Belongs to the protein kinase superfamily. (131 aa)
Tab1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (254 aa)
Ppp2r1bSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (693 aa)
Mapk11Mitogen-activated protein kinase. (355 aa)
Nod1Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (953 aa)
Tab3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X2. (715 aa)
Dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (379 aa)
ENSMAUP00000001261annotation not available (61 aa)
ENSMAUP00000002256annotation not available (75 aa)
Rps6ka2Ribosomal protein S6 kinase. (733 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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