STRINGSTRING
Jun Jun Mapk1 Mapk1 Mapk10 Mapk10 Mapk14 Mapk14 Fosl2 Fosl2 Mapk3 Mapk3 Creb5 Creb5 Mapk8 Mapk8 Mapk9 Mapk9 Atf2 Atf2 Fos Fos Atf7 Atf7 Mapk11 Mapk11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JunTranscription factor AP-1; Belongs to the bZIP family. (338 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Fosl2Fos-related antigen 2. (324 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X3. (508 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa)
FosProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
Atf7Cyclic AMP-dependent transcription factor ATF-7. (385 aa)
Mapk11Mitogen-activated protein kinase. (355 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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