STRINGSTRING
Psmd1 Psmd1 Psmb11 Psmb11 Psmc4 Psmc4 ENSMAUP00000007836 ENSMAUP00000007836 ENSMAUP00000007909 ENSMAUP00000007909 Psmb7 Psmb7 Psma2 Psma2 Anapc16 Anapc16 Crebzf Crebzf Cdc14a Cdc14a ENSMAUP00000009902 ENSMAUP00000009902 Psma4 Psma4 Psma7 Psma7 Fbxo43 Fbxo43 Psme4 Psme4 Anapc2 Anapc2 Psmd9 Psmd9 Psmd7 Psmd7 Mad2l1 Mad2l1 Psmd6 Psmd6 Psmf1 Psmf1 Aurkc Aurkc Psmd10 Psmd10 Psmc5 Psmc5 ENSMAUP00000012811 ENSMAUP00000012811 Ccna1 Ccna1 Plk1 Plk1 Cdc20 Cdc20 Psmd12 Psmd12 Cdc27 Cdc27 Ube2s Ube2s Psmd14 Psmd14 Psmd3 Psmd3 Cdk3 Cdk3 Psmd2 Psmd2 Psmd5 Psmd5 Aurka Aurka Psma1 Psma1 LOC101823019 LOC101823019 Psmc2 Psmc2 Rps27a Rps27a Psmc6 Psmc6 Psmb9 Psmb9 Nek2 Nek2 Psmc3 Psmc3 ENSMAUP00000004913 ENSMAUP00000004913 ENSMAUP00000004398 ENSMAUP00000004398 Ube2c Ube2c Psmb8 Psmb8 Kxd1 Kxd1 Skp2 Skp2 ENSMAUP00000002256 ENSMAUP00000002256 Skp1 Skp1 Ccnb1 Ccnb1 Psmd13 Psmd13 Cdc16 Cdc16 LOC101832726 LOC101832726 Kiaa2012 Kiaa2012 Fzr1 Fzr1 Fbxo5 Fbxo5 ENSMAUP00000007258 ENSMAUP00000007258 Cul1 Cul1 Ube2d1 Ube2d1 Psmb2 Psmb2 ENSMAUP00000024812 ENSMAUP00000024812 Bub1b Bub1b Rb1 Rb1 Cdc23 Cdc23 Psma3 Psma3 Anapc7 Anapc7 Cdk1 Cdk1 Psmb6 Psmb6 Pttg1 Pttg1 Aurkb Aurkb ENSMAUP00000022538 ENSMAUP00000022538 Psma6 Psma6 Psmd4 Psmd4 ENSMAUP00000022314 ENSMAUP00000022314 Psmc1 Psmc1 Cdc26 Cdc26 Cdk2 Cdk2 Anapc15 Anapc15 Psma5 Psma5 Psmb3 Psmb3 Anapc11 Anapc11 Psmd11 Psmd11 Psmd8 Psmd8 ENSMAUP00000020392 ENSMAUP00000020392 Bub3 Bub3 Anapc1 Anapc1 Ccna2 Ccna2 Anapc5 Anapc5 ENSMAUP00000019431 ENSMAUP00000019431 Psmb5 Psmb5 Fam89a Fam89a LOC101832350 LOC101832350 Psma8 Psma8 Anapc10 Anapc10 Tm7sf3 Tm7sf3 Psme2 Psme2 Psme1 Psme1 Psmb4 Psmb4 Ube2e1 Ube2e1 Psme3 Psme3 Fam89b Fam89b ENSMAUP00000016290 ENSMAUP00000016290 ENSMAUP00000016715 ENSMAUP00000016715 Anapc4 Anapc4 Btrc Btrc Psmb1 Psmb1 LOC101837857 LOC101837857
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
Psmb11Proteasome subunit beta. (280 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
ENSMAUP00000007836annotation not available (57 aa)
ENSMAUP00000007909annotation not available (237 aa)
Psmb7Proteasome subunit beta. (277 aa)
Psma2Proteasome subunit alpha type. (245 aa)
Anapc16Anaphase-promoting complex subunit 16. (94 aa)
CrebzfCREB/ATF bZIP transcription factor isoform X2. (356 aa)
Cdc14aDual specificity protein phosphatase CDC14A isoform X1. (625 aa)
ENSMAUP00000009902annotation not available (163 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Psma7Proteasome subunit alpha type. (145 aa)
Fbxo43F-box only protein 43 isoform X1. (634 aa)
Psme4Proteasome activator complex subunit 4 isoform X3. (1843 aa)
Anapc2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (833 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (202 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (320 aa)
Mad2l1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
Psmf1Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
AurkcAurora kinase C. (118 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (227 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
ENSMAUP00000012811annotation not available (405 aa)
Ccna1cyclin-A1; Belongs to the cyclin family. (421 aa)
Plk1Serine/threonine-protein kinase PLK. (602 aa)
Cdc20Cell division cycle protein 20 homolog. (499 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (308 aa)
Cdc27Cell division cycle protein 27 homolog. (680 aa)
Ube2sUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (221 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (530 aa)
Cdk3Cyclin-dependent kinase 3 isoform X2; Belongs to the protein kinase superfamily. (297 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa)
Psmd526S proteasome non-ATPase regulatory subunit 5. (504 aa)
AurkaAurora kinase A; Belongs to the protein kinase superfamily. (401 aa)
Psma1Proteasome subunit alpha type. (206 aa)
LOC101823019Ubiquitin-like. (114 aa)
Psmc2Proteasome 26S subunit, ATPase 2. (349 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa)
Psmb9Proteasome subunit beta. (219 aa)
Nek2Serine/threonine-protein kinase Nek2. (442 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa)
ENSMAUP00000004913annotation not available (165 aa)
ENSMAUP00000004398annotation not available (164 aa)
Ube2cUbiquitin-conjugating enzyme E2C. (135 aa)
Psmb8Proteasome subunit beta. (276 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Skp2S-phase kinase-associated protein 2. (354 aa)
ENSMAUP00000002256annotation not available (75 aa)
Skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (158 aa)
Ccnb1G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (447 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
Cdc16Cell division cycle protein 16 homolog isoform X1. (620 aa)
LOC101832726S-phase kinase-associated protein 1 pseudogene. (144 aa)
Kiaa2012LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog. (835 aa)
Fzr1Fizzy-related protein homolog. (493 aa)
Fbxo5F-box only protein 5. (424 aa)
ENSMAUP00000007258annotation not available (117 aa)
Cul1Cullin-1; Belongs to the cullin family. (776 aa)
Ube2d1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
Psmb2Proteasome subunit beta. (201 aa)
ENSMAUP00000024812annotation not available (115 aa)
Bub1bMitotic checkpoint serine/threonine-protein kinase BUB1 beta. (1011 aa)
Rb1Retinoblastoma-associated protein. (906 aa)
Cdc23Cell division cycle protein 23 homolog. (580 aa)
Psma3Proteasome subunit alpha type. (180 aa)
Anapc7Anaphase-promoting complex subunit 7. (540 aa)
Cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
Psmb6Proteasome subunit beta. (238 aa)
Pttg1Securin. (200 aa)
AurkbAurora kinase B isoform X1; Belongs to the protein kinase superfamily. (339 aa)
ENSMAUP00000022538annotation not available (95 aa)
Psma6Proteasome subunit alpha type. (246 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa)
ENSMAUP00000022314annotation not available (101 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa)
Cdc26Anaphase-promoting complex subunit CDC26. (85 aa)
Cdk2Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa)
Anapc15Anaphase-promoting complex subunit 15 isoform X1. (141 aa)
Psma5Proteasome subunit alpha type. (241 aa)
Psmb3Proteasome subunit beta. (202 aa)
Anapc11Anaphase-promoting complex subunit 11. (47 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (419 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (180 aa)
ENSMAUP00000020392annotation not available (68 aa)
Bub3Mitotic checkpoint protein BUB3. (326 aa)
Anapc1Anaphase-promoting complex subunit 1. (1666 aa)
Ccna2Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. Belongs to the cyclin family. Cyclin AB subfamily. (421 aa)
Anapc5Anaphase-promoting complex subunit 5. (84 aa)
ENSMAUP00000019431annotation not available (150 aa)
Psmb5Proteasome subunit beta. (256 aa)
Fam89aProtein FAM89A. (183 aa)
LOC101832350Aurora kinase C-like. (108 aa)
Psma8Proteasome subunit alpha type. (237 aa)
Anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
Tm7sf3Transmembrane 7 superfamily member 3. (493 aa)
Psme2Proteasome activator complex subunit 2. (239 aa)
Psme1Proteasome activator complex subunit 1. (249 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Ube2e1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
Psme3Proteasome activator complex subunit 3. (254 aa)
Fam89bProtein FAM89B. (189 aa)
ENSMAUP00000016290annotation not available (246 aa)
ENSMAUP00000016715annotation not available (418 aa)
Anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa)
BtrcF-box/WD repeat-containing protein 1A isoform X2. (605 aa)
Psmb1Proteasome subunit beta. (240 aa)
LOC101837857Cell division cycle protein 27 homolog. (204 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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