STRINGSTRING
ENSMAUP00000022314 ENSMAUP00000022314 Prkn Prkn ENSMAUP00000002256 ENSMAUP00000002256 ENSMAUP00000001870 ENSMAUP00000001870 Traf2 Traf2 LOC101842058 LOC101842058 Ripk1 Ripk1 Tradd Tradd Kxd1 Kxd1 LOC101825710 LOC101825710 Ttc6 Ttc6 Casp3 Casp3 Ube2l3 Ube2l3 Npvf Npvf LOC106021303 LOC106021303 Chmp4c Chmp4c Rps27a Rps27a Faslg Faslg LOC101823019 LOC101823019 Cdc37 Cdc37 Ripk3 Ripk3 Fas Fas ENSMAUP00000007258 ENSMAUP00000007258 Chmp3 Chmp3 Irf2 Irf2 Irf1 Irf1 ENSMAUP00000008197 ENSMAUP00000008197 Casp1 Casp1 Chmp6 Chmp6 ENSMAUP00000009202 ENSMAUP00000009202 Gsdmd Gsdmd Elane Elane ENSMAUP00000011696 ENSMAUP00000011696 ENSMAUP00000012115 ENSMAUP00000012115 Peli1 Peli1 LOC101825446 LOC101825446 Il18 Il18 ENSMAUP00000014485 ENSMAUP00000014485 Tnfsf10 Tnfsf10 Flot1 Flot1 ENSMAUP00000015967 ENSMAUP00000015967 Bax Bax LOC101843738 LOC101843738 Chmp2a Chmp2a LOC101839247 LOC101839247 Flot2 Flot2 Sdcbp Sdcbp Pdcd6ip Pdcd6ip Cyct Cyct Il1b Il1b Fadd Fadd ENSMAUP00000019431 ENSMAUP00000019431 Chmp7 Chmp7 Birc2 Birc2 Mlkl Mlkl Gsdme Gsdme Xiap Xiap Bak1 Bak1 Casp8 Casp8 Il1a Il1a ENSMAUP00000021279 ENSMAUP00000021279 Birc7 Birc7 Hmgb1 Hmgb1 Cflar Cflar Chmp4b Chmp4b Stub1 Stub1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAUP00000022314annotation not available (101 aa)
PrknRBR-type E3 ubiquitin transferase. (123 aa)
ENSMAUP00000002256annotation not available (75 aa)
ENSMAUP00000001870annotation not available (99 aa)
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
LOC101842058Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (658 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (310 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
LOC101825710LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 1b-like. (1162 aa)
Ttc6Tetratricopeptide repeat protein 6. (1737 aa)
Casp3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (246 aa)
Ube2l3Ubiquitin-conjugating enzyme E2 L3 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
Npvfpro-FMRFamide-related neuropeptide VF. (189 aa)
LOC106021303Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
Chmp4cCharged multivesicular body protein 4c. (98 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
FaslgTumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa)
LOC101823019Ubiquitin-like. (114 aa)
Cdc37Hsp90 co-chaperone Cdc37. (379 aa)
Ripk3Receptor-interacting serine/threonine-protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (483 aa)
FasTumor necrosis factor receptor superfamily member 6 isoform X1. (323 aa)
ENSMAUP00000007258annotation not available (117 aa)
Chmp3Charged multivesicular body protein 3. (197 aa)
Irf2Interferon regulatory factor. (349 aa)
Irf1Interferon regulatory factor. (132 aa)
ENSMAUP00000008197annotation not available (303 aa)
Casp1Caspase-1-like; Belongs to the peptidase C14A family. (313 aa)
Chmp6Charged multivesicular body protein 6. (200 aa)
ENSMAUP00000009202annotation not available (164 aa)
Gsdmdgasdermin-D isoform X1. (486 aa)
ElaneNeutrophil elastase-like; Belongs to the peptidase S1 family. (265 aa)
ENSMAUP00000011696annotation not available (450 aa)
ENSMAUP00000012115annotation not available (87 aa)
Peli1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
LOC101825446Baculoviral IAP repeat-containing protein 1a-like. (953 aa)
Il18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (197 aa)
ENSMAUP00000014485annotation not available (178 aa)
Tnfsf10Tumor necrosis factor ligand superfamily member. (289 aa)
Flot1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
ENSMAUP00000015967annotation not available (113 aa)
BaxApoptosis regulator BAX isoform X1. (192 aa)
LOC101843738UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit. (1049 aa)
Chmp2aCharged multivesicular body protein 2a. (222 aa)
LOC101839247Magnesium-dependent phosphatase 1. (164 aa)
Flot2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
SdcbpSyntenin-1 isoform X1. (275 aa)
Pdcd6ipProgrammed cell death 6-interacting protein isoform X1. (873 aa)
CyctCytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ENSMAUP00000019431annotation not available (150 aa)
Chmp7Charged multivesicular body protein 7. (450 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (592 aa)
MlklMixed lineage kinase domain-like protein. (439 aa)
GsdmeNon-syndromic hearing impairment protein 5. (499 aa)
XiapE3 ubiquitin-protein ligase XIAP. (496 aa)
Bak1Bcl-2 homologous antagonist/killer. (209 aa)
Casp8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa)
Il1aInterleukin-1; Belongs to the IL-1 family. (269 aa)
ENSMAUP00000021279annotation not available (98 aa)
Birc7Baculoviral IAP repeat-containing protein 7. (285 aa)
Hmgb1High mobility group protein B1. (219 aa)
CflarCASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (219 aa)
Chmp4bCharged multivesicular body protein 4b. (224 aa)
Stub1E3 ubiquitin-protein ligase CHIP isoform X1. (303 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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