STRINGSTRING
Psmf1 Psmf1 Psmd10 Psmd10 Psmc5 Psmc5 Efcab7 Efcab7 Psmd12 Psmd12 Arrb2 Arrb2 Dzip1l Dzip1l Dzip1 Dzip1 Dhh Dhh Psmd14 Psmd14 Kif3a Kif3a ENSMAUP00000014436 ENSMAUP00000014436 Psmd3 Psmd3 Psmd2 Psmd2 Smurf1 Smurf1 Evc Evc Itch Itch Csnk1a1 Csnk1a1 Psmd13 Psmd13 Spop Spop ENSMAUP00000002256 ENSMAUP00000002256 Boc Boc Kxd1 Kxd1 Psmb8 Psmb8 ENSMAUP00000003260 ENSMAUP00000003260 Ulk3 Ulk3 ENSMAUP00000004913 ENSMAUP00000004913 Psmc3 Psmc3 Gas8 Gas8 Psmb9 Psmb9 Gpr161 Gpr161 Spopl Spopl Psmc6 Psmc6 Rps27a Rps27a Psmc2 Psmc2 LOC101823019 LOC101823019 Psma1 Psma1 Psmd5 Psmd5 Gli2 Gli2 ENSMAUP00000007258 ENSMAUP00000007258 Psmc4 Psmc4 ENSMAUP00000007909 ENSMAUP00000007909 Psmb7 Psmb7 Psma2 Psma2 Gli3 Gli3 Smo Smo Glis1 Glis1 Crebzf Crebzf Smurf2 Smurf2 Rbx1 Rbx1 Cul3 Cul3 Gli1 Gli1 Ihh Ihh Evc2 Evc2 Ptch1 Ptch1 Psme2 Psme2 Psme1 Psme1 Psmb4 Psmb4 Psme3 Psme3 ENSMAUP00000016290 ENSMAUP00000016290 Psmb1 Psmb1 Psmd1 Psmd1 Shh Shh Sufu Sufu Psmb11 Psmb11 Numb Numb ENSMAUP00000019431 ENSMAUP00000019431 Psmb5 Psmb5 Psma8 Psma8 Arrb1 Arrb1 Psmb2 Psmb2 Cdc73 Cdc73 Psma3 Psma3 Psmb6 Psmb6 Iqce Iqce ENSMAUP00000022538 ENSMAUP00000022538 Psma6 Psma6 Psmd4 Psmd4 ENSMAUP00000022314 ENSMAUP00000022314 Psmc1 Psmc1 Gas1 Gas1 Cdon Cdon Psma5 Psma5 Psmb3 Psmb3 Psmd11 Psmd11 Psmd8 Psmd8 Grk2 Grk2 ENSMAUP00000020392 ENSMAUP00000020392 Psma4 Psma4 Psma7 Psma7 Psme4 Psme4 Numbl Numbl Psmd9 Psmd9 Psmd7 Psmd7 Kif7 Kif7 Psmd6 Psmd6 Hhip Hhip
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Psmf1Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (227 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
Efcab7EF-hand calcium-binding domain-containing protein 7. (628 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (308 aa)
Arrb2Beta-arrestin-2. (279 aa)
Dzip1lZinc finger protein DZIP1L. (125 aa)
Dzip1Zinc finger protein DZIP1-like. (695 aa)
DhhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Kif3aKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
ENSMAUP00000014436annotation not available (114 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (530 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa)
Smurf1E3 ubiquitin-protein ligase. (679 aa)
EvcEllis-van Creveld syndrome protein isoform X1. (1004 aa)
ItchE3 ubiquitin-protein ligase. (841 aa)
Csnk1a1Casein kinase I isoform X3; Belongs to the protein kinase superfamily. (336 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
SpopSpeckle type BTB/POZ protein. (340 aa)
ENSMAUP00000002256annotation not available (75 aa)
BocBrother of CDO isoform X3. (1108 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Psmb8Proteasome subunit beta. (276 aa)
ENSMAUP00000003260annotation not available (95 aa)
Ulk3Serine/threonine-protein kinase ULK3 isoform X2; Belongs to the protein kinase superfamily. (472 aa)
ENSMAUP00000004913annotation not available (165 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa)
Gas8Growth arrest-specific protein 8. (467 aa)
Psmb9Proteasome subunit beta. (219 aa)
Gpr161G-protein coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (543 aa)
SpoplSpeckle-type POZ protein-like isoform X1. (392 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Psmc2Proteasome 26S subunit, ATPase 2. (349 aa)
LOC101823019Ubiquitin-like. (114 aa)
Psma1Proteasome subunit alpha type. (206 aa)
Psmd526S proteasome non-ATPase regulatory subunit 5. (504 aa)
Gli2Zinc finger protein GLI2. (1544 aa)
ENSMAUP00000007258annotation not available (117 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
ENSMAUP00000007909annotation not available (237 aa)
Psmb7Proteasome subunit beta. (277 aa)
Psma2Proteasome subunit alpha type. (245 aa)
Gli3Transcriptional activator GLI3. (1582 aa)
SmoSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (757 aa)
Glis1Zinc finger protein GLIS1 isoform X1. (794 aa)
CrebzfCREB/ATF bZIP transcription factor isoform X2. (356 aa)
Smurf2E3 ubiquitin-protein ligase. (67 aa)
Rbx1E3 ubiquitin-protein ligase RBX1. (108 aa)
Cul3Cullin-3; Belongs to the cullin family. (761 aa)
Gli1Zinc finger protein GLI1. (981 aa)
IhhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (363 aa)
Evc2Limbin. (1215 aa)
Ptch1Protein patched homolog 1. (1440 aa)
Psme2Proteasome activator complex subunit 2. (239 aa)
Psme1Proteasome activator complex subunit 1. (249 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psme3Proteasome activator complex subunit 3. (254 aa)
ENSMAUP00000016290annotation not available (246 aa)
Psmb1Proteasome subunit beta. (240 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
ShhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (439 aa)
SufuSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (458 aa)
Psmb11Proteasome subunit beta. (280 aa)
NumbProtein numb homolog isoform X1. (663 aa)
ENSMAUP00000019431annotation not available (150 aa)
Psmb5Proteasome subunit beta. (256 aa)
Psma8Proteasome subunit alpha type. (237 aa)
Arrb1Beta-arrestin-1 isoform X3. (418 aa)
Psmb2Proteasome subunit beta. (201 aa)
Cdc73Parafibromin. (531 aa)
Psma3Proteasome subunit alpha type. (180 aa)
Psmb6Proteasome subunit beta. (238 aa)
IqceIQ domain-containing protein E isoform X3. (768 aa)
ENSMAUP00000022538annotation not available (95 aa)
Psma6Proteasome subunit alpha type. (246 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa)
ENSMAUP00000022314annotation not available (101 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa)
Gas1Growth arrest-specific protein 1. (341 aa)
CdonCell adhesion molecule-related/down-regulated by oncogenes isoform X1. (1254 aa)
Psma5Proteasome subunit alpha type. (241 aa)
Psmb3Proteasome subunit beta. (202 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (419 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (180 aa)
Grk2Beta-adrenergic receptor kinase 1; Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation- independent manner. Positively regulates ciliary smoothened (SMO)- dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity. Belongs to the protei [...] (689 aa)
ENSMAUP00000020392annotation not available (68 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Psma7Proteasome subunit alpha type. (145 aa)
Psme4Proteasome activator complex subunit 4 isoform X3. (1843 aa)
NumblNumb-like protein isoform X1. (602 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (202 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (320 aa)
Kif7Kinesin-like protein KIF7. (1297 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
HhipHedgehog-interacting protein isoform X1. (700 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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