STRINGSTRING
Rbx1 Rbx1 ENSMAUP00000009986 ENSMAUP00000009986 Sumo1 Sumo1 Ino80b Ino80b Wbp1 Wbp1 Wdr76 Wdr76 Tceanc2 Tceanc2 Meiob Meiob Cops2 Cops2 Gtf2h5 Gtf2h5 Cetn3 Cetn3 Gtf2h4 Gtf2h4 Aqr Aqr Polr2a Polr2a LOC101823893 LOC101823893 Actr5 Actr5 Ino80 Ino80 Xrcc1 Xrcc1 Ppie Ppie Tfpt Tfpt ENSMAUP00000016955 ENSMAUP00000016955 Ube2i Ube2i Gps1 Gps1 Ercc8 Ercc8 Rfc1 Rfc1 Cops6 Cops6 Actr8 Actr8 Vtcn1 Vtcn1 Ercc1 Ercc1 Cops7a Cops7a Polr2d Polr2d Pold3 Pold3 Spocd1 Spocd1 Ino80c Ino80c Cdk7 Cdk7 Nfatc2ip Nfatc2ip Cops5 Cops5 Rcbtb2 Rcbtb2 Mcrs1 Mcrs1 Xpa Xpa ENSMAUP00000012929 ENSMAUP00000012929 Polr2g Polr2g Polr2j Polr2j Gtf2h3 Gtf2h3 Ddb1 Ddb1 Rnf111 Rnf111 Lig1 Lig1 Prpf19 Prpf19 Tcea2 Tcea2 Zfp830 Zfp830 Ino80d Ino80d Ercc5 Ercc5 ENSMAUP00000021238 ENSMAUP00000021238 Polr2l Polr2l Actl6a Actl6a Rad23b Rad23b Mnat1 Mnat1 Pole Pole Tcea3 Tcea3 Nrde2 Nrde2 Polr2f Polr2f Usp40 Usp40 Rpap3 Rpap3 Pias3 Pias3 Ercc4 Ercc4 Sumo2 Sumo2 Uvssa Uvssa ENSMAUP00000019431 ENSMAUP00000019431 Polr2b Polr2b Bivm Bivm Ccnh Ccnh Cops3 Cops3 Hmgn2 Hmgn2 Tcea1 Tcea1 Nfrkb Nfrkb Polk Polk Cops8 Cops8 Xab2 Xab2 Rfc3 Rfc3 Polr2h Polr2h Parp2 Parp2 Yy2 Yy2 Pold4 Pold4 ENSMAUP00000000181 ENSMAUP00000000181 Phf3 Phf3 LOC106023063 LOC106023063 Pole3 Pole3 Rpa3 Rpa3 Ercc2 Ercc2 Pias1 Pias1 Polr2c Polr2c AW551984 AW551984 ENSMAUP00000001221 ENSMAUP00000001221 Polr2i Polr2i Pole2 Pole2 Ruvbl1 Ruvbl1 ENSMAUP00000002060 ENSMAUP00000002060 ENSMAUP00000002256 ENSMAUP00000002256 Actg1 Actg1 Pole4 Pole4 Cul4b Cul4b Kxd1 Kxd1 Rpa2 Rpa2 Ppp1r42 Ppp1r42 ENSMAUP00000003260 ENSMAUP00000003260 Ube2n Ube2n Pold1 Pold1 Cetn2 Cetn2 Ep300 Ep300 Ercc3 Ercc3 Rfc4 Rfc4 Chd1l Chd1l Zfp42 Zfp42 Ube2v2 Ube2v2 ENSMAUP00000005402 ENSMAUP00000005402 Vwa5b1 Vwa5b1 Usp45 Usp45 Rcbtb1 Rcbtb1 Atad5 Atad5 ENSMAUP00000022314 ENSMAUP00000022314 Cops7b Cops7b LOC101823019 LOC101823019 Pold2 Pold2 Ercc6 Ercc6 Parp1 Parp1 Usp7 Usp7 Upk3bl Upk3bl Rps27a Rps27a Cops7b-2 Cops7b-2 Xpc Xpc Lig3 Lig3 ENSMAUP00000022826 ENSMAUP00000022826 ENSMAUP00000006950 ENSMAUP00000006950 Isy1 Isy1 Vwa5b2 Vwa5b2 ENSMAUP00000007258 ENSMAUP00000007258 Yy1 Yy1 Rad23a Rad23a Gtf2h1 Gtf2h1 Tceanc Tceanc Hmgn1 Hmgn1 ENSMAUP00000008237 ENSMAUP00000008237 Sumo3 Sumo3 Ino80e Ino80e Polr2e Polr2e Ddb2 Ddb2 Parp3 Parp3 Polr2k Polr2k LOC101840076 LOC101840076 Gtf2h2 Gtf2h2 Rpa1 Rpa1 Gm36028 Gm36028 Pcna Pcna
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rbx1E3 ubiquitin-protein ligase RBX1. (108 aa)
ENSMAUP00000009986annotation not available (173 aa)
Sumo1Small ubiquitin-related modifier. (97 aa)
Ino80bINO80 complex subunit B isoform X2. (374 aa)
Wbp1WW domain-binding protein 1 isoform X1. (303 aa)
Wdr76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (620 aa)
Tceanc2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
MeiobMeiosis-specific with OB domain-containing protein isoform X1. (470 aa)
Cops2COP9 signalosome complex subunit 2 isoform X1. (450 aa)
Gtf2h5General transcription factor IIH subunit 5. (71 aa)
Cetn3Centrin-3. (167 aa)
Gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
AqrRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1298 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (987 aa)
LOC101823893Von Willebrand factor A domain-containing protein 5A-like. (713 aa)
Actr5Actin-related protein 5; Belongs to the actin family. (414 aa)
Ino80DNA helicase INO80. (1548 aa)
Xrcc1DNA repair protein XRCC1. (628 aa)
PpiePeptidyl-prolyl cis-trans isomerase E. (169 aa)
TfptTCF3 fusion partner. (259 aa)
ENSMAUP00000016955annotation not available (61 aa)
Ube2iSUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451 (By similarity). Can catalyze the formation of poly-SUMO chains (By similarity). Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5 (By similarity). Sumoylates p53/TP53 at 'Lys-386' (By similarity). Mediates sumoylation of ERCC6 which is essential for its transcription-coupled [...] (158 aa)
Gps1COP9 signalosome complex subunit 1 isoform X3. (526 aa)
Ercc8DNA excision repair protein ERCC-8 isoform X1. (397 aa)
Rfc1Replication factor C subunit 1. (1063 aa)
Cops6COP9 signalosome complex subunit 6. (322 aa)
Actr8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
Vtcn1V-set domain-containing T-cell activation inhibitor 1. (282 aa)
Ercc1DNA excision repair protein ERCC-1. (297 aa)
Cops7aCOP9 signalosome complex subunit 7a. (277 aa)
Polr2dDNA-directed RNA polymerase II subunit RPB4. (142 aa)
Pold3DNA polymerase delta subunit 3 isoform X1. (462 aa)
Spocd1SPOC domain-containing protein 1. (576 aa)
Ino80cINO80 complex subunit C isoform X2. (191 aa)
Cdk7Cyclin dependent kinase 7. (224 aa)
Nfatc2ipLOW QUALITY PROTEIN: NFATC2-interacting protein. (406 aa)
Cops5COP9 signalosome complex subunit 5. (321 aa)
Rcbtb2RCC1 and BTB domain-containing protein 2 isoform X4. (551 aa)
Mcrs1Microspherule protein 1 isoform X1. (462 aa)
XpaDNA repair protein complementing XP-A cells isoform X2. (271 aa)
ENSMAUP00000012929annotation not available (90 aa)
Polr2gDNA-directed RNA polymerase II subunit RPB7. (94 aa)
Polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
Gtf2h3General transcription factor IIH subunit 3. (309 aa)
Ddb1DNA damage-binding protein 1 isoform X2. (1140 aa)
Rnf111E3 ubiquitin-protein ligase Arkadia isoform X3. (990 aa)
Lig1DNA ligase. (931 aa)
Prpf19pre-mRNA-processing factor 19 isoform X1. (523 aa)
Tcea2Transcription elongation factor A protein 2 isoform X4. (299 aa)
Zfp830Zinc finger protein 830. (361 aa)
Ino80dINO80 complex subunit D. (946 aa)
Ercc5DNA repair protein complementing XP-G cells. (1179 aa)
ENSMAUP00000021238annotation not available (247 aa)
Polr2lDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
Actl6aActin like 6A. (204 aa)
Rad23bUV excision repair protein RAD23 homolog B. (415 aa)
Mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (228 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (663 aa)
Tcea3Transcription elongation factor A protein 3. (348 aa)
Nrde2Protein NRDE2 homolog. (1167 aa)
Polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X2. (127 aa)
Usp40Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (93 aa)
Rpap3RNA polymerase II-associated protein 3. (661 aa)
Pias3E3 SUMO-protein ligase PIAS3 isoform X2. (90 aa)
Ercc4DNA repair endonuclease XPF. (913 aa)
Sumo2Small ubiquitin-related modifier 2 isoform X1. (75 aa)
UvssaUV-stimulated scaffold protein A. (706 aa)
ENSMAUP00000019431annotation not available (150 aa)
Polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1175 aa)
BivmBasic immunoglobulin-like variable motif-containing protein isoform X1. (503 aa)
Ccnhcyclin-H; Belongs to the cyclin family. (324 aa)
Cops3COP9 signalosome complex subunit 3 isoform X2. (423 aa)
Hmgn2Non-histone chromosomal protein HMG-17. (90 aa)
Tcea1Transcription elongation factor A protein 1. (300 aa)
NfrkbNuclear factor related to kappa-B-binding protein isoform X6. (1294 aa)
PolkDNA polymerase kappa. (856 aa)
Cops8COP9 signalosome complex subunit 8. (209 aa)
Xab2pre-mRNA-splicing factor SYF1. (855 aa)
Rfc3Replication factor C subunit 3. (356 aa)
Polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
Parp2Poly [ADP-ribose] polymerase. (561 aa)
Yy2Transcription factor YY2. (372 aa)
Pold4DNA polymerase delta subunit 4. (74 aa)
ENSMAUP00000000181annotation not available (111 aa)
Phf3PHD finger protein 3. (154 aa)
LOC106023063General transcription factor IIH subunit 1-like. (86 aa)
Pole3DNA polymerase epsilon subunit 3. (146 aa)
Rpa3Replication protein A 14 kDa subunit. (121 aa)
Ercc2TFIIH basal transcription factor complex helicase XPD subunit. (741 aa)
Pias1E3 SUMO-protein ligase PIAS1 isoform X2. (651 aa)
Polr2cDNA-directed RNA polymerase II subunit RPB3. (250 aa)
AW551984Von Willebrand factor A domain-containing protein 5A. (807 aa)
ENSMAUP00000001221annotation not available (406 aa)
Polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
Pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (461 aa)
Ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ENSMAUP00000002060annotation not available (103 aa)
ENSMAUP00000002256annotation not available (75 aa)
Actg1Actin gamma 1. (133 aa)
Pole4DNA polymerase epsilon subunit 4. (124 aa)
Cul4bcullin-4B; Belongs to the cullin family. (555 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Rpa2Replication protein A 32 kDa subunit. (270 aa)
Ppp1r42Protein phosphatase 1 regulatory subunit 42 isoform X1. (357 aa)
ENSMAUP00000003260annotation not available (95 aa)
Ube2nUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
Pold1DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol- delta4), displays differences in catalytic activity. Most notably, expresses higher pro [...] (1101 aa)
Cetn2Centrin-2. (172 aa)
Ep300Histone acetyltransferase p300 isoform X3. (2417 aa)
Ercc3TFIIH basal transcription factor complex helicase XPB subunit. (783 aa)
Rfc4Replication factor C subunit 4. (362 aa)
Chd1lchromodomain-helicase-DNA-binding protein 1-like. (393 aa)
Zfp42Zinc finger protein 42 homolog. (271 aa)
Ube2v2Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. (146 aa)
ENSMAUP00000005402annotation not available (100 aa)
Vwa5b1Von Willebrand factor A domain-containing protein 5B1. (1210 aa)
Usp45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (812 aa)
Rcbtb1RCC1 and BTB domain-containing protein 1 isoform X2. (531 aa)
Atad5ATPase family AAA domain-containing protein 5. (1819 aa)
ENSMAUP00000022314annotation not available (101 aa)
Cops7bCOP9 signalosome complex subunit 7b. (227 aa)
LOC101823019Ubiquitin-like. (114 aa)
Pold2DNA polymerase delta subunit 2 isoform X2. (260 aa)
Ercc6DNA excision repair protein ERCC-6. (1236 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
Usp7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (496 aa)
Upk3blUroplakin-3b-like protein. (276 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Cops7b-2LOW QUALITY PROTEIN: COP9 signalosome complex subunit 7b. (69 aa)
XpcXeroderma pigmentosum, complementation group C. (723 aa)
Lig3DNA ligase. (1003 aa)
ENSMAUP00000022826annotation not available (193 aa)
ENSMAUP00000006950annotation not available (259 aa)
Isy1pre-mRNA-splicing factor ISY1 homolog. (285 aa)
Vwa5b2Von Willebrand factor A domain-containing protein 5B2 isoform X2. (1247 aa)
ENSMAUP00000007258annotation not available (117 aa)
Yy1Transcriptional repressor protein YY1. (283 aa)
Rad23aUV excision repair protein RAD23 homolog A. (187 aa)
Gtf2h1General transcription factor IIH subunit 1. (236 aa)
TceancTranscription elongation factor A N-terminal and central domain-containing protein. (359 aa)
Hmgn1Non-histone chromosomal protein HMG-14. (97 aa)
ENSMAUP00000008237annotation not available (79 aa)
Sumo3Small ubiquitin-related modifier. (110 aa)
Ino80eINO80 complex subunit E isoform X1. (244 aa)
Polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1. (216 aa)
Ddb2DNA damage-binding protein 2 isoform X1. (387 aa)
Parp3Poly [ADP-ribose] polymerase. (531 aa)
Polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
LOC101840076DNA-directed RNA polymerase II subunit RPB1. (543 aa)
Gtf2h2General transcription factor IIH subunit. (194 aa)
Rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (601 aa)
Gm36028Predicted gene, 36028. (308 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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