STRINGSTRING
Rps27a Rps27a Chd1l Chd1l Polk Polk Bivm Bivm ENSMAUP00000019431 ENSMAUP00000019431 Ercc4 Ercc4 Pole Pole Ercc5 Ercc5 Rcbtb1 Rcbtb1 ENSMAUP00000022314 ENSMAUP00000022314 Pcna Pcna Rbx1 Rbx1 ENSMAUP00000003260 ENSMAUP00000003260 Rpa2 Rpa2 Kxd1 Kxd1 Cul4b Cul4b Pole4 Pole4 ENSMAUP00000002256 ENSMAUP00000002256 ENSMAUP00000002060 ENSMAUP00000002060 Pole2 Pole2 ENSMAUP00000001221 ENSMAUP00000001221 Ercc2 Ercc2 Rpa3 Rpa3 Pole3 Pole3 LOC106023063 LOC106023063 ENSMAUP00000022826 ENSMAUP00000022826 Gtf2h4 Gtf2h4 Rfc4 Rfc4 Ercc3 Ercc3 Pold1 Pold1 Gtf2h5 Gtf2h5 Rpa1 Rpa1 Ddb1 Ddb1 Gtf2h3 Gtf2h3 Xpa Xpa Rcbtb2 Rcbtb2 Pold3 Pold3 Ercc1 Ercc1 Rfc1 Rfc1 ENSMAUP00000016955 ENSMAUP00000016955 Pold4 Pold4 Parp2 Parp2 Rfc3 Rfc3 Gtf2h2 Gtf2h2 Parp3 Parp3 Ddb2 Ddb2 Gtf2h1 Gtf2h1 ENSMAUP00000007258 ENSMAUP00000007258 ENSMAUP00000006950 ENSMAUP00000006950 LOC101823019 LOC101823019 Pold2 Pold2 Parp1 Parp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Chd1lchromodomain-helicase-DNA-binding protein 1-like. (393 aa)
PolkDNA polymerase kappa. (856 aa)
BivmBasic immunoglobulin-like variable motif-containing protein isoform X1. (503 aa)
ENSMAUP00000019431annotation not available (150 aa)
Ercc4DNA repair endonuclease XPF. (913 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (663 aa)
Ercc5DNA repair protein complementing XP-G cells. (1179 aa)
Rcbtb1RCC1 and BTB domain-containing protein 1 isoform X2. (531 aa)
ENSMAUP00000022314annotation not available (101 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Rbx1E3 ubiquitin-protein ligase RBX1. (108 aa)
ENSMAUP00000003260annotation not available (95 aa)
Rpa2Replication protein A 32 kDa subunit. (270 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Cul4bcullin-4B; Belongs to the cullin family. (555 aa)
Pole4DNA polymerase epsilon subunit 4. (124 aa)
ENSMAUP00000002256annotation not available (75 aa)
ENSMAUP00000002060annotation not available (103 aa)
Pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (461 aa)
ENSMAUP00000001221annotation not available (406 aa)
Ercc2TFIIH basal transcription factor complex helicase XPD subunit. (741 aa)
Rpa3Replication protein A 14 kDa subunit. (121 aa)
Pole3DNA polymerase epsilon subunit 3. (146 aa)
LOC106023063General transcription factor IIH subunit 1-like. (86 aa)
ENSMAUP00000022826annotation not available (193 aa)
Gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
Rfc4Replication factor C subunit 4. (362 aa)
Ercc3TFIIH basal transcription factor complex helicase XPB subunit. (783 aa)
Pold1DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol- delta4), displays differences in catalytic activity. Most notably, expresses higher pro [...] (1101 aa)
Gtf2h5General transcription factor IIH subunit 5. (71 aa)
Rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (601 aa)
Ddb1DNA damage-binding protein 1 isoform X2. (1140 aa)
Gtf2h3General transcription factor IIH subunit 3. (309 aa)
XpaDNA repair protein complementing XP-A cells isoform X2. (271 aa)
Rcbtb2RCC1 and BTB domain-containing protein 2 isoform X4. (551 aa)
Pold3DNA polymerase delta subunit 3 isoform X1. (462 aa)
Ercc1DNA excision repair protein ERCC-1. (297 aa)
Rfc1Replication factor C subunit 1. (1063 aa)
ENSMAUP00000016955annotation not available (61 aa)
Pold4DNA polymerase delta subunit 4. (74 aa)
Parp2Poly [ADP-ribose] polymerase. (561 aa)
Rfc3Replication factor C subunit 3. (356 aa)
Gtf2h2General transcription factor IIH subunit. (194 aa)
Parp3Poly [ADP-ribose] polymerase. (531 aa)
Ddb2DNA damage-binding protein 2 isoform X1. (387 aa)
Gtf2h1General transcription factor IIH subunit 1. (236 aa)
ENSMAUP00000007258annotation not available (117 aa)
ENSMAUP00000006950annotation not available (259 aa)
LOC101823019Ubiquitin-like. (114 aa)
Pold2DNA polymerase delta subunit 2 isoform X2. (260 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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