STRINGSTRING
Pole4 Pole4 ENSMAUP00000002256 ENSMAUP00000002256 ENSMAUP00000002060 ENSMAUP00000002060 Pole2 Pole2 Polr2i Polr2i ENSMAUP00000001221 ENSMAUP00000001221 Polr2c Polr2c Ercc2 Ercc2 Rpa3 Rpa3 Pole3 Pole3 LOC106023063 LOC106023063 Phf3 Phf3 ENSMAUP00000000181 ENSMAUP00000000181 Tceanc2 Tceanc2 Meiob Meiob Gtf2h5 Gtf2h5 Gtf2h4 Gtf2h4 Aqr Aqr Polr2a Polr2a Ppie Ppie ENSMAUP00000022826 ENSMAUP00000022826 ENSMAUP00000022314 ENSMAUP00000022314 Atad5 Atad5 Rcbtb1 Rcbtb1 Ercc5 Ercc5 ENSMAUP00000021238 ENSMAUP00000021238 Polr2l Polr2l Mnat1 Mnat1 Pole Pole Tcea3 Tcea3 Nrde2 Nrde2 Polr2f Polr2f Usp40 Usp40 Ercc4 Ercc4 Uvssa Uvssa ENSMAUP00000019431 ENSMAUP00000019431 Polr2b Polr2b Bivm Bivm Ccnh Ccnh Hmgn2 Hmgn2 Tcea1 Tcea1 Polk Polk Xab2 Xab2 Rfc3 Rfc3 Polr2h Polr2h Pold4 Pold4 ENSMAUP00000016955 ENSMAUP00000016955 Ercc8 Ercc8 Rfc1 Rfc1 Ercc1 Ercc1 Polr2d Polr2d Pold3 Pold3 Spocd1 Spocd1 Cdk7 Cdk7 Rcbtb2 Rcbtb2 Xpa Xpa Polr2g Polr2g Polr2j Polr2j Gtf2h3 Gtf2h3 Ddb1 Ddb1 Prpf19 Prpf19 Tcea2 Tcea2 Zfp830 Zfp830 ENSMAUP00000009986 ENSMAUP00000009986 Rbx1 Rbx1 Pcna Pcna Rpa1 Rpa1 Gtf2h2 Gtf2h2 LOC101840076 LOC101840076 Polr2k Polr2k Polr2e Polr2e ENSMAUP00000008237 ENSMAUP00000008237 Hmgn1 Hmgn1 Tceanc Tceanc Gtf2h1 Gtf2h1 ENSMAUP00000007258 ENSMAUP00000007258 Isy1 Isy1 ENSMAUP00000006950 ENSMAUP00000006950 LOC101823019 LOC101823019 Pold2 Pold2 Ercc6 Ercc6 Usp7 Usp7 Upk3bl Upk3bl Rps27a Rps27a Rfc4 Rfc4 Ercc3 Ercc3 Ep300 Ep300 Pold1 Pold1 ENSMAUP00000003260 ENSMAUP00000003260 Rpa2 Rpa2 Kxd1 Kxd1 Cul4b Cul4b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Pole4DNA polymerase epsilon subunit 4. (124 aa)
ENSMAUP00000002256annotation not available (75 aa)
ENSMAUP00000002060annotation not available (103 aa)
Pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (461 aa)
Polr2iDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ENSMAUP00000001221annotation not available (406 aa)
Polr2cDNA-directed RNA polymerase II subunit RPB3. (250 aa)
Ercc2TFIIH basal transcription factor complex helicase XPD subunit. (741 aa)
Rpa3Replication protein A 14 kDa subunit. (121 aa)
Pole3DNA polymerase epsilon subunit 3. (146 aa)
LOC106023063General transcription factor IIH subunit 1-like. (86 aa)
Phf3PHD finger protein 3. (154 aa)
ENSMAUP00000000181annotation not available (111 aa)
Tceanc2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
MeiobMeiosis-specific with OB domain-containing protein isoform X1. (470 aa)
Gtf2h5General transcription factor IIH subunit 5. (71 aa)
Gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
AqrRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1298 aa)
Polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (987 aa)
PpiePeptidyl-prolyl cis-trans isomerase E. (169 aa)
ENSMAUP00000022826annotation not available (193 aa)
ENSMAUP00000022314annotation not available (101 aa)
Atad5ATPase family AAA domain-containing protein 5. (1819 aa)
Rcbtb1RCC1 and BTB domain-containing protein 1 isoform X2. (531 aa)
Ercc5DNA repair protein complementing XP-G cells. (1179 aa)
ENSMAUP00000021238annotation not available (247 aa)
Polr2lDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
Mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (228 aa)
PoleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (663 aa)
Tcea3Transcription elongation factor A protein 3. (348 aa)
Nrde2Protein NRDE2 homolog. (1167 aa)
Polr2fDNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X2. (127 aa)
Usp40Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (93 aa)
Ercc4DNA repair endonuclease XPF. (913 aa)
UvssaUV-stimulated scaffold protein A. (706 aa)
ENSMAUP00000019431annotation not available (150 aa)
Polr2bDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1175 aa)
BivmBasic immunoglobulin-like variable motif-containing protein isoform X1. (503 aa)
Ccnhcyclin-H; Belongs to the cyclin family. (324 aa)
Hmgn2Non-histone chromosomal protein HMG-17. (90 aa)
Tcea1Transcription elongation factor A protein 1. (300 aa)
PolkDNA polymerase kappa. (856 aa)
Xab2pre-mRNA-splicing factor SYF1. (855 aa)
Rfc3Replication factor C subunit 3. (356 aa)
Polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
Pold4DNA polymerase delta subunit 4. (74 aa)
ENSMAUP00000016955annotation not available (61 aa)
Ercc8DNA excision repair protein ERCC-8 isoform X1. (397 aa)
Rfc1Replication factor C subunit 1. (1063 aa)
Ercc1DNA excision repair protein ERCC-1. (297 aa)
Polr2dDNA-directed RNA polymerase II subunit RPB4. (142 aa)
Pold3DNA polymerase delta subunit 3 isoform X1. (462 aa)
Spocd1SPOC domain-containing protein 1. (576 aa)
Cdk7Cyclin dependent kinase 7. (224 aa)
Rcbtb2RCC1 and BTB domain-containing protein 2 isoform X4. (551 aa)
XpaDNA repair protein complementing XP-A cells isoform X2. (271 aa)
Polr2gDNA-directed RNA polymerase II subunit RPB7. (94 aa)
Polr2jDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
Gtf2h3General transcription factor IIH subunit 3. (309 aa)
Ddb1DNA damage-binding protein 1 isoform X2. (1140 aa)
Prpf19pre-mRNA-processing factor 19 isoform X1. (523 aa)
Tcea2Transcription elongation factor A protein 2 isoform X4. (299 aa)
Zfp830Zinc finger protein 830. (361 aa)
ENSMAUP00000009986annotation not available (173 aa)
Rbx1E3 ubiquitin-protein ligase RBX1. (108 aa)
PcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
Rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (601 aa)
Gtf2h2General transcription factor IIH subunit. (194 aa)
LOC101840076DNA-directed RNA polymerase II subunit RPB1. (543 aa)
Polr2kDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
Polr2eDNA-directed RNA polymerases I, II, and III subunit RPABC1. (216 aa)
ENSMAUP00000008237annotation not available (79 aa)
Hmgn1Non-histone chromosomal protein HMG-14. (97 aa)
TceancTranscription elongation factor A N-terminal and central domain-containing protein. (359 aa)
Gtf2h1General transcription factor IIH subunit 1. (236 aa)
ENSMAUP00000007258annotation not available (117 aa)
Isy1pre-mRNA-splicing factor ISY1 homolog. (285 aa)
ENSMAUP00000006950annotation not available (259 aa)
LOC101823019Ubiquitin-like. (114 aa)
Pold2DNA polymerase delta subunit 2 isoform X2. (260 aa)
Ercc6DNA excision repair protein ERCC-6. (1236 aa)
Usp7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (496 aa)
Upk3blUroplakin-3b-like protein. (276 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Rfc4Replication factor C subunit 4. (362 aa)
Ercc3TFIIH basal transcription factor complex helicase XPB subunit. (783 aa)
Ep300Histone acetyltransferase p300 isoform X3. (2417 aa)
Pold1DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol- delta4), displays differences in catalytic activity. Most notably, expresses higher pro [...] (1101 aa)
ENSMAUP00000003260annotation not available (95 aa)
Rpa2Replication protein A 32 kDa subunit. (270 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Cul4bcullin-4B; Belongs to the cullin family. (555 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (24%) [HD]