STRINGSTRING
Psma6 Psma6 Psmd4 Psmd4 ENSMAUP00000022314 ENSMAUP00000022314 Psmc1 Psmc1 Cdk2 Cdk2 Psma5 Psma5 Psmb3 Psmb3 Psmd11 Psmd11 Psmd8 Psmd8 Mnat1 Mnat1 ENSMAUP00000020392 ENSMAUP00000020392 Cdkn1b Cdkn1b Ccna2 Ccna2 Cdkn1c Cdkn1c ENSMAUP00000019431 ENSMAUP00000019431 Ccnd1 Ccnd1 Psmb5 Psmb5 Ccnh Ccnh Psmd1 Psmd1 Akt3 Akt3 Psmb1 Psmb1 ENSMAUP00000016290 ENSMAUP00000016290 Psme3 Psme3 Psmb4 Psmb4 Psme1 Psme1 Psme2 Psme2 ENSMAUP00000015385 ENSMAUP00000015385 Psmd2 Psmd2 Cdk3 Cdk3 Psmd3 Psmd3 Cdk7 Cdk7 Psmd14 Psmd14 Akt2 Akt2 Rb1 Rb1 Cables1 Cables1 Ptk6 Ptk6 Psmb2 Psmb2 Psmd12 Psmd12 Wee2 Wee2 Ccna1 Ccna1 Akt1 Akt1 Psmc5 Psmc5 Psmd10 Psmd10 Wee1 Wee1 Psmf1 Psmf1 Psmd6 Psmd6 Psmd7 Psmd7 Ccne2 Ccne2 Psmd9 Psmd9 Psma7 Psma7 Psma4 Psma4 Cks1b Cks1b ENSMAUP00000009902 ENSMAUP00000009902 Crebzf Crebzf Cdk4 Cdk4 Cks2 Cks2 Psma2 Psma2 Psmb7 Psmb7 ENSMAUP00000007909 ENSMAUP00000007909 ENSMAUP00000007836 ENSMAUP00000007836 Psmc4 Psmc4 ENSMAUP00000007258 ENSMAUP00000007258 Cul1 Cul1 Psmd5 Psmd5 Psma1 Psma1 LOC101823019 LOC101823019 ENSMAUP00000002256 ENSMAUP00000002256 Skp2 Skp2 Kxd1 Kxd1 Ccne1 Ccne1 Psmb8 Psmb8 ENSMAUP00000003205 ENSMAUP00000003205 ENSMAUP00000004913 ENSMAUP00000004913 Psmc3 Psmc3 Psmb9 Psmb9 Psmc6 Psmc6 Rps27a Rps27a Psmc2 Psmc2 Skp1 Skp1 Psmd13 Psmd13 Cdkn1a Cdkn1a Kiaa2012 Kiaa2012 LOC101832726 LOC101832726 Psma3 Psma3 Psmb6 Psmb6 ENSMAUP00000022538 ENSMAUP00000022538
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Psma6Proteasome subunit alpha type. (246 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa)
ENSMAUP00000022314annotation not available (101 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa)
Cdk2Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa)
Psma5Proteasome subunit alpha type. (241 aa)
Psmb3Proteasome subunit beta. (202 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (419 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (180 aa)
Mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (228 aa)
ENSMAUP00000020392annotation not available (68 aa)
Cdkn1bCyclin-dependent kinase inhibitor 1B. (198 aa)
Ccna2Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. Belongs to the cyclin family. Cyclin AB subfamily. (421 aa)
Cdkn1cCyclin-dependent kinase inhibitor 1C isoform X2. (348 aa)
ENSMAUP00000019431annotation not available (150 aa)
Ccnd1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
Psmb5Proteasome subunit beta. (256 aa)
Ccnhcyclin-H; Belongs to the cyclin family. (324 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Psmb1Proteasome subunit beta. (240 aa)
ENSMAUP00000016290annotation not available (246 aa)
Psme3Proteasome activator complex subunit 3. (254 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psme1Proteasome activator complex subunit 1. (249 aa)
Psme2Proteasome activator complex subunit 2. (239 aa)
ENSMAUP00000015385annotation not available (72 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa)
Cdk3Cyclin-dependent kinase 3 isoform X2; Belongs to the protein kinase superfamily. (297 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (530 aa)
Cdk7Cyclin dependent kinase 7. (224 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Rb1Retinoblastoma-associated protein. (906 aa)
Cables1CDK5 and ABL1 enzyme substrate 1 isoform X2. (534 aa)
Ptk6Tyrosine-protein kinase. (451 aa)
Psmb2Proteasome subunit beta. (201 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (308 aa)
Wee2Wee1-like protein kinase. (550 aa)
Ccna1cyclin-A1; Belongs to the cyclin family. (421 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (227 aa)
Wee1Wee1-like protein kinase. (645 aa)
Psmf1Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (320 aa)
Ccne2G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (202 aa)
Psma7Proteasome subunit alpha type. (145 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Cks1bCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
ENSMAUP00000009902annotation not available (163 aa)
CrebzfCREB/ATF bZIP transcription factor isoform X2. (356 aa)
Cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
Cks2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
Psma2Proteasome subunit alpha type. (245 aa)
Psmb7Proteasome subunit beta. (277 aa)
ENSMAUP00000007909annotation not available (237 aa)
ENSMAUP00000007836annotation not available (57 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
ENSMAUP00000007258annotation not available (117 aa)
Cul1Cullin-1; Belongs to the cullin family. (776 aa)
Psmd526S proteasome non-ATPase regulatory subunit 5. (504 aa)
Psma1Proteasome subunit alpha type. (206 aa)
LOC101823019Ubiquitin-like. (114 aa)
ENSMAUP00000002256annotation not available (75 aa)
Skp2S-phase kinase-associated protein 2. (354 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Ccne1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
Psmb8Proteasome subunit beta. (276 aa)
ENSMAUP00000003205annotation not available (93 aa)
ENSMAUP00000004913annotation not available (165 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa)
Psmb9Proteasome subunit beta. (219 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Psmc2Proteasome 26S subunit, ATPase 2. (349 aa)
Skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (158 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
Cdkn1aCyclin-dependent kinase inhibitor 1. (163 aa)
Kiaa2012LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog. (835 aa)
LOC101832726S-phase kinase-associated protein 1 pseudogene. (144 aa)
Psma3Proteasome subunit alpha type. (180 aa)
Psmb6Proteasome subunit beta. (238 aa)
ENSMAUP00000022538annotation not available (95 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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