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| | Ube2e1 | Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | Rad21 | Double-strand-break repair protein rad21 homolog. (631 aa) |
| | Mcm6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | Pds5b | Sister chromatid cohesion protein PDS5 homolog B isoform X1. (1449 aa) |
| | Pole3 | DNA polymerase epsilon subunit 3. (146 aa) |
| | Rpa3 | Replication protein A 14 kDa subunit. (121 aa) |
| | ENSMAUP00000001221 | annotation not available (406 aa) |
| | Fzr1 | Fizzy-related protein homolog. (493 aa) |
| | Cdkn1a | Cyclin-dependent kinase inhibitor 1. (163 aa) |
| | Kiaa2012 | LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog. (835 aa) |
| | Pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (461 aa) |
| | Rad21l1 | Double-strand-break repair protein rad21-like protein 1. (552 aa) |
| | LOC101832726 | S-phase kinase-associated protein 1 pseudogene. (144 aa) |
| | Cdc16 | Cell division cycle protein 16 homolog isoform X1. (620 aa) |
| | Psmd13 | 26S proteasome non-ATPase regulatory subunit 13. (369 aa) |
| | ENSMAUP00000002060 | annotation not available (103 aa) |
| | Skp1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (158 aa) |
| | ENSMAUP00000002256 | annotation not available (75 aa) |
| | Skp2 | S-phase kinase-associated protein 2. (354 aa) |
| | Pole4 | DNA polymerase epsilon subunit 4. (124 aa) |
| | Kxd1 | ubiquitin-60S ribosomal protein L40. (232 aa) |
| | Rpa2 | Replication protein A 32 kDa subunit. (270 aa) |
| | Dna2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1005 aa) |
| | Ccne1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | Psmb8 | Proteasome subunit beta. (276 aa) |
| | ENSMAUP00000003205 | annotation not available (93 aa) |
| | ENSMAUP00000003260 | annotation not available (95 aa) |
| | Pold1 | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol- delta4), displays differences in catalytic activity. Most notably, expresses higher pro [...] (1101 aa) |
| | Gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | Cdc6 | Cell division control protein 6 homolog isoform X2. (418 aa) |
| | Tcerg1l | Transcription elongation regulator 1-like protein. (593 aa) |
| | Rfc4 | Replication factor C subunit 4. (362 aa) |
| | Gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | Ube2c | Ubiquitin-conjugating enzyme E2C. (135 aa) |
| | ENSMAUP00000004398 | annotation not available (164 aa) |
| | Pola1 | DNA polymerase. (1193 aa) |
| | ENSMAUP00000004913 | annotation not available (165 aa) |
| | Psmc3 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa) |
| | Psmb9 | Proteasome subunit beta. (219 aa) |
| | Psmc6 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa) |
| | Gins1 | DNA replication complex GINS protein PSF1 isoform X1. (196 aa) |
| | Rps27a | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | Psmc2 | Proteasome 26S subunit, ATPase 2. (349 aa) |
| | Pold2 | DNA polymerase delta subunit 2 isoform X2. (260 aa) |
| | LOC101823019 | Ubiquitin-like. (114 aa) |
| | Psma1 | Proteasome subunit alpha type. (206 aa) |
| | Gins3 | DNA replication complex GINS protein PSF3. (215 aa) |
| | Stag1 | Cohesin subunit SA-1. (1258 aa) |
| | Psmd5 | 26S proteasome non-ATPase regulatory subunit 5. (504 aa) |
| | Mcm2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | Orc6 | Origin recognition complex subunit 6. (253 aa) |
| | ENSMAUP00000006950 | annotation not available (259 aa) |
| | Prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (416 aa) |
| | Cul1 | Cullin-1; Belongs to the cullin family. (776 aa) |
| | ENSMAUP00000007258 | annotation not available (117 aa) |
| | Psmc4 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | ENSMAUP00000007836 | annotation not available (57 aa) |
| | ENSMAUP00000007909 | annotation not available (237 aa) |
| | Psmb7 | Proteasome subunit beta. (277 aa) |
| | Prim2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (507 aa) |
| | Psma2 | Proteasome subunit alpha type. (245 aa) |
| | Wapl | Wings apart-like protein homolog. (1153 aa) |
| | Anapc16 | Anaphase-promoting complex subunit 16. (94 aa) |
| | Cks2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | Rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (601 aa) |
| | Cdk4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | Crebzf | CREB/ATF bZIP transcription factor isoform X2. (356 aa) |
| | Pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | Rbx1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
| | ENSMAUP00000009902 | annotation not available (163 aa) |
| | Orc5 | Origin recognition complex subunit 5. (418 aa) |
| | Pds5a | Sister chromatid cohesion protein PDS5 homolog A isoform X1. (1285 aa) |
| | Cks1b | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | Psma4 | Proteasome subunit alpha type. (261 aa) |
| | Psma7 | Proteasome subunit alpha type. (145 aa) |
| | Psme4 | Proteasome activator complex subunit 4 isoform X3. (1843 aa) |
| | Stag2 | Cohesin subunit SA-2 isoform X1. (1268 aa) |
| | Anapc2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (833 aa) |
| | Psmd9 | 26S proteasome non-ATPase regulatory subunit 9. (202 aa) |
| | Ccne2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | Psmd7 | 26S proteasome non-ATPase regulatory subunit 7. (320 aa) |
| | Psmd6 | 26S proteasome non-ATPase regulatory subunit 6. (389 aa) |
| | Fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | Psmf1 | Proteasome inhibitor PI31 subunit isoform X1. (271 aa) |
| | Wee1 | Wee1-like protein kinase. (645 aa) |
| | Psmd10 | 26S proteasome non-ATPase regulatory subunit 10 isoform X1. (227 aa) |
| | Psmc5 | 26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa) |
| | Lig1 | DNA ligase. (931 aa) |
| | Mcm3 | DNA helicase; Belongs to the MCM family. (806 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Ccna1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | Orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (847 aa) |
| | Wee2 | Wee1-like protein kinase. (550 aa) |
| | Psmd12 | 26S proteasome non-ATPase regulatory subunit 12. (308 aa) |
| | Cdc25b | M-phase inducer phosphatase 2. (575 aa) |
| | Cdc27 | Cell division cycle protein 27 homolog. (680 aa) |
| | Rcbtb2 | RCC1 and BTB domain-containing protein 2 isoform X4. (551 aa) |
| | Ube2s | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (221 aa) |
| | Orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | Mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (704 aa) |
| | Psmd14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | Cdk7 | Cyclin dependent kinase 7. (224 aa) |
| | Cdca5 | Sororin. (248 aa) |
| | Psmd3 | 26S proteasome non-ATPase regulatory subunit 3. (530 aa) |
| | Cdk3 | Cyclin-dependent kinase 3 isoform X2; Belongs to the protein kinase superfamily. (297 aa) |
| | Psmd2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa) |
| | Pold3 | DNA polymerase delta subunit 3 isoform X1. (462 aa) |
| | Anapc10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | Smc3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | Tm7sf3 | Transmembrane 7 superfamily member 3. (493 aa) |
| | ENSMAUP00000015385 | annotation not available (72 aa) |
| | Gmnn | Geminin DNA replication inhibitor. (141 aa) |
| | Psme2 | Proteasome activator complex subunit 2. (239 aa) |
| | Psme1 | Proteasome activator complex subunit 1. (249 aa) |
| | Pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa) |
| | Psmb4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | Mcm9 | DNA helicase MCM9; Belongs to the MCM family. (1125 aa) |
| | Psme3 | Proteasome activator complex subunit 3. (254 aa) |
| | Fam89b | Protein FAM89B. (189 aa) |
| | ENSMAUP00000016290 | annotation not available (246 aa) |
| | ENSMAUP00000016366 | annotation not available (191 aa) |
| | Rfc1 | Replication factor C subunit 1. (1063 aa) |
| | Anapc4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (812 aa) |
| | Pold4 | DNA polymerase delta subunit 4. (74 aa) |
| | Psmb1 | Proteasome subunit beta. (240 aa) |
| | LOC101837857 | Cell division cycle protein 27 homolog. (204 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Psmd1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa) |
| | Rfc3 | Replication factor C subunit 3. (356 aa) |
| | Mcm8 | DNA helicase MCM8 isoform X1; Belongs to the MCM family. (833 aa) |
| | Smc1a | Structural maintenance of chromosomes protein. (1233 aa) |
| | Psmb11 | Proteasome subunit beta. (280 aa) |
| | Psma8 | Proteasome subunit alpha type. (237 aa) |
| | Ccnh | cyclin-H; Belongs to the cyclin family. (324 aa) |
| | Fam89a | Protein FAM89A. (183 aa) |
| | Psmb5 | Proteasome subunit beta. (256 aa) |
| | Ccnd1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | ENSMAUP00000019431 | annotation not available (150 aa) |
| | Cdkn1c | Cyclin-dependent kinase inhibitor 1C isoform X2. (348 aa) |
| | Anapc5 | Anaphase-promoting complex subunit 5. (84 aa) |
| | Ccna2 | Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. Belongs to the cyclin family. Cyclin AB subfamily. (421 aa) |
| | Anapc1 | Anaphase-promoting complex subunit 1. (1666 aa) |
| | Cdkn1b | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | ENSMAUP00000020392 | annotation not available (68 aa) |
| | Pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (663 aa) |
| | Mnat1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (228 aa) |
| | Esco1 | N-acetyltransferase ESCO1. (835 aa) |
| | Tm4sf19 | Transmembrane 4 L6 family member 19. (206 aa) |
| | Esco2 | LOW QUALITY PROTEIN: N-acetyltransferase ESCO2. (597 aa) |
| | Mcm4 | DNA helicase; Belongs to the MCM family. (862 aa) |
| | Psmd8 | 26S proteasome non-ATPase regulatory subunit 8. (180 aa) |
| | Psmd11 | 26S proteasome non-ATPase regulatory subunit 11. (419 aa) |
| | Anapc11 | Anaphase-promoting complex subunit 11. (47 aa) |
| | Psmb3 | Proteasome subunit beta. (202 aa) |
| | Psma5 | Proteasome subunit alpha type. (241 aa) |
| | Anapc15 | Anaphase-promoting complex subunit 15 isoform X1. (141 aa) |
| | Cdk2 | Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa) |
| | Orc2 | Origin recognition complex subunit 2 isoform X1. (565 aa) |
| | Rcbtb1 | RCC1 and BTB domain-containing protein 1 isoform X2. (531 aa) |
| | Cdc26 | Anaphase-promoting complex subunit CDC26. (85 aa) |
| | Atad5 | ATPase family AAA domain-containing protein 5. (1819 aa) |
| | Psmc1 | 26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa) |
| | ENSMAUP00000022314 | annotation not available (101 aa) |
| | Psmd4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa) |
| | Psma6 | Proteasome subunit alpha type. (246 aa) |
| | ENSMAUP00000022538 | annotation not available (95 aa) |
| | ENSMAUP00000022826 | annotation not available (193 aa) |
| | Psmb6 | Proteasome subunit beta. (238 aa) |
| | Mcm5 | DNA helicase; Belongs to the MCM family. (708 aa) |
| | Anapc7 | Anaphase-promoting complex subunit 7. (540 aa) |
| | Psma3 | Proteasome subunit alpha type. (180 aa) |
| | Cdc23 | Cell division cycle protein 23 homolog. (580 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Rb1 | Retinoblastoma-associated protein. (906 aa) |
| | Cables1 | CDK5 and ABL1 enzyme substrate 1 isoform X2. (534 aa) |
| | Ptk6 | Tyrosine-protein kinase. (451 aa) |
| | Psmb2 | Proteasome subunit beta. (201 aa) |
| | Meiob | Meiosis-specific with OB domain-containing protein isoform X1. (470 aa) |
| | Ube2d1 | Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | Cdt1 | DNA replication factor Cdt1. (541 aa) |
