STRINGSTRING
Mapkapk2 Mapkapk2 Clip4 Clip4 LOC101825446 LOC101825446 Tnf Tnf ENSMAUP00000014680 ENSMAUP00000014680 Ulk2 Ulk2 Birc7 Birc7 Tnfaip3 Tnfaip3 ENSMAUP00000022314 ENSMAUP00000022314 Cflar Cflar Sppl2c Sppl2c Nfatc4 Nfatc4 Stub1 Stub1 Spata2 Spata2 Sppl2b Sppl2b Map3k20 Map3k20 Usp2 Usp2 Tab1 Tab1 Usp4 Usp4 Ube2d1 Ube2d1 ENSMAUP00000011696 ENSMAUP00000011696 Rack1 Rack1 Tab2 Tab2 ENSMAUP00000008459 ENSMAUP00000008459 Tmem198b Tmem198b Otud1 Otud1 ENSMAUP00000008197 ENSMAUP00000008197 Usp21 Usp21 Ube2d2 Ube2d2 Madd Madd ENSMAUP00000007258 ENSMAUP00000007258 Smpd2 Smpd2 Ube2d2b Ube2d2b Ikbkg Ikbkg LOC101823019 LOC101823019 Ikbke Ikbke Bag4 Bag4 Nsmaf Nsmaf Ube2d3 Ube2d3 Rps27a Rps27a Otulinl Otulinl Ube2l3 Ube2l3 Ikbkb Ikbkb ENSMAUP00000015826 ENSMAUP00000015826 Fadd Fadd ENSMAUP00000019431 ENSMAUP00000019431 Rnf31 Rnf31 Birc2 Birc2 Xiap Xiap Traf1 Traf1 Casp8 Casp8 Mib2 Mib2 Adam17 Adam17 ENSMAUP00000020843 ENSMAUP00000020843 Rbck1 Rbck1 Map3k7 Map3k7 Otud7b Otud7b Clip3 Clip3 Chuk Chuk Sppl2a Sppl2a Optn Optn Smpd5 Smpd5 Tmem198 Tmem198 Wdr31 Wdr31 Tradd Tradd ENSMAUP00000000511 ENSMAUP00000000511 Ripk1 Ripk1 Tbk1 Tbk1 Tab3 Tab3 Smpd3 Smpd3 Traf2 Traf2 Cyld Cyld ENSMAUP00000002256 ENSMAUP00000002256 Kxd1 Kxd1 Tnfrsf1a Tnfrsf1a LOC101825710 LOC101825710 Sharpin Sharpin Ulk1 Ulk1 Otulin Otulin
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mapkapk2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (386 aa)
Clip4CAP-Gly domain-containing linker protein 4. (704 aa)
LOC101825446Baculoviral IAP repeat-containing protein 1a-like. (953 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ENSMAUP00000014680annotation not available (140 aa)
Ulk2Serine/threonine-protein kinase ULK2. (1023 aa)
Birc7Baculoviral IAP repeat-containing protein 7. (285 aa)
Tnfaip3Tumor necrosis factor alpha-induced protein 3 isoform X1. (776 aa)
ENSMAUP00000022314annotation not available (101 aa)
CflarCASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (219 aa)
Sppl2cSignal peptide peptidase-like 2C. (579 aa)
Nfatc4Nuclear factor of activated T-cells, cytoplasmic 4. (728 aa)
Stub1E3 ubiquitin-protein ligase CHIP isoform X1. (303 aa)
Spata2Spermatogenesis-associated protein 2. (521 aa)
Sppl2bSignal peptide peptidase-like 2B isoform X4. (579 aa)
Map3k20Mitogen-activated protein kinase kinase kinase 20. (762 aa)
Usp2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (317 aa)
Tab1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1. (254 aa)
Usp4Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
Ube2d1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ENSMAUP00000011696annotation not available (450 aa)
Rack1Receptor of activated protein C kinase 1. (147 aa)
Tab2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa)
ENSMAUP00000008459annotation not available (113 aa)
Tmem198bLOW QUALITY PROTEIN: transmembrane protein 198-like. (345 aa)
Otud1OTU domain-containing protein 1. (405 aa)
ENSMAUP00000008197annotation not available (303 aa)
Usp21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (567 aa)
Ube2d2Ubiquitin-conjugating enzyme E2 D2 isoform X2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
MaddMAP kinase activating death domain. (1253 aa)
ENSMAUP00000007258annotation not available (117 aa)
Smpd2Sphingomyelin phosphodiesterase 2. (419 aa)
Ube2d2bUbiquitin-conjugating enzyme E2 D2B; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
IkbkgNF-kappa-B essential modulator isoform X1. (412 aa)
LOC101823019Ubiquitin-like. (114 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (715 aa)
Bag4BAG family molecular chaperone regulator 4 isoform X2. (455 aa)
NsmafProtein FAN. (876 aa)
Ube2d3Ubiquitin-conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
OtulinlOTU deubiquitinase with linear linkage specificity like. (203 aa)
Ube2l3Ubiquitin-conjugating enzyme E2 L3 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa)
ENSMAUP00000015826annotation not available (113 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ENSMAUP00000019431annotation not available (150 aa)
Rnf31E3 ubiquitin-protein ligase RNF31. (1065 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (592 aa)
XiapE3 ubiquitin-protein ligase XIAP. (496 aa)
Traf1TNF receptor-associated factor. (410 aa)
Casp8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa)
Mib2E3 ubiquitin-protein ligase MIB2. (901 aa)
Adam17Disintegrin and metalloproteinase domain-containing protein 17 isoform X1. (827 aa)
ENSMAUP00000020843annotation not available (239 aa)
Rbck1ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X2. (503 aa)
Map3k7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (497 aa)
Otud7bOTU domain-containing protein 7B. (596 aa)
Clip3CAP-Gly domain-containing linker protein 3. (547 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
Sppl2aSignal peptide peptidase-like 2A isoform X2. (524 aa)
OptnOptineurin. (513 aa)
Smpd5Sphingomyelin phosphodiesterase 5. (487 aa)
Tmem198Transmembrane protein 198. (360 aa)
Wdr31WD repeat-containing protein 31. (112 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (310 aa)
ENSMAUP00000000511annotation not available (91 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (658 aa)
Tbk1Serine/threonine-protein kinase TBK1. (729 aa)
Tab3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X2. (715 aa)
Smpd3Sphingomyelin phosphodiesterase 3. (655 aa)
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CyldUbiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (956 aa)
ENSMAUP00000002256annotation not available (75 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (468 aa)
LOC101825710LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 1b-like. (1162 aa)
SharpinSharpin. (154 aa)
Ulk1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1040 aa)
OtulinUbiquitin thioesterase otulin. (315 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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