STRINGSTRING
Psmd1 Psmd1 Psmb1 Psmb1 Tuba8 Tuba8 ENSMAUP00000016715 ENSMAUP00000016715 ENSMAUP00000016290 ENSMAUP00000016290 Psme3 Psme3 Cdkn1a Cdkn1a Psmd13 Psmd13 Tubb3 Tubb3 Hsp90ab1 Hsp90ab1 Tubb2a Tubb2a Mapre1 Mapre1 Psmd8 Psmd8 Psmd11 Psmd11 Psmb3 Psmb3 Psma5 Psma5 Psmc1 Psmc1 ENSMAUP00000022314 ENSMAUP00000022314 Psmd4 Psmd4 Psma6 Psma6 ENSMAUP00000022538 ENSMAUP00000022538 Psmb6 Psmb6 Cdk1 Cdk1 ENSMAUP00000023426 ENSMAUP00000023426 Gtse1 Gtse1 Psma3 Psma3 Psmb2 Psmb2 ENSMAUP00000025679 ENSMAUP00000025679 Tp53 Tp53 ENSMAUP00000020392 ENSMAUP00000020392 LOC106020738 LOC106020738 Ccnb1 Ccnb1 Kxd1 Kxd1 ENSMAUP00000002946 ENSMAUP00000002946 Psmb8 Psmb8 Tubb4b Tubb4b ENSMAUP00000004541 ENSMAUP00000004541 Psma7 Psma7 ENSMAUP00000004913 ENSMAUP00000004913 Psmc3 Psmc3 Psmb9 Psmb9 Psmc6 Psmc6 Rps27a Rps27a Tubb4a Tubb4a Ccnb2 Ccnb2 Psmb4 Psmb4 Psme1 Psme1 Psme2 Psme2 Psmd2 Psmd2 Psmd3 Psmd3 Psmd14 Psmd14 Psmd12 Psmd12 Plk1 Plk1 Psmc5 Psmc5 Psmd10 Psmd10 Psmf1 Psmf1 Psmd6 Psmd6 Psmd7 Psmd7 Psmd9 Psmd9 Psme4 Psme4 Psmc2 Psmc2 Tubal3 Tubal3 LOC101823019 LOC101823019 Psma1 Psma1 Psmd5 Psmd5 ENSMAUP00000007160 ENSMAUP00000007160 ENSMAUP00000007258 ENSMAUP00000007258 Psmc4 Psmc4 ENSMAUP00000007909 ENSMAUP00000007909 Psmb7 Psmb7 Psma2 Psma2 ENSMAUP00000008492 ENSMAUP00000008492 Tuba4a Tuba4a Psma4 Psma4 Tubb6 Tubb6 Tubb1 Tubb1 ENSMAUP00000000935 ENSMAUP00000000935 LOC101831620 LOC101831620 ENSMAUP00000019431 ENSMAUP00000019431 Psmb5 Psmb5 Psma8 Psma8 Psmb11 Psmb11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
Psmb1Proteasome subunit beta. (240 aa)
Tuba8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (397 aa)
ENSMAUP00000016715annotation not available (418 aa)
ENSMAUP00000016290annotation not available (246 aa)
Psme3Proteasome activator complex subunit 3. (254 aa)
Cdkn1aCyclin-dependent kinase inhibitor 1. (163 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
Tubb3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
Hsp90ab1Heat shock protein HSP 90-beta. (724 aa)
Tubb2aTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
Mapre1Microtubule-associated protein RP/EB family member 1. (97 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (180 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (419 aa)
Psmb3Proteasome subunit beta. (202 aa)
Psma5Proteasome subunit alpha type. (241 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa)
ENSMAUP00000022314annotation not available (101 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa)
Psma6Proteasome subunit alpha type. (246 aa)
ENSMAUP00000022538annotation not available (95 aa)
Psmb6Proteasome subunit beta. (238 aa)
Cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
ENSMAUP00000023426annotation not available (405 aa)
Gtse1G2 and S phase-expressed protein 1. (742 aa)
Psma3Proteasome subunit alpha type. (180 aa)
Psmb2Proteasome subunit beta. (201 aa)
ENSMAUP00000025679annotation not available (108 aa)
Tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (395 aa)
ENSMAUP00000020392annotation not available (68 aa)
LOC106020738Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family. (100 aa)
Ccnb1G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (447 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
ENSMAUP00000002946annotation not available (431 aa)
Psmb8Proteasome subunit beta. (276 aa)
Tubb4bTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ENSMAUP00000004541annotation not available (622 aa)
Psma7Proteasome subunit alpha type. (145 aa)
ENSMAUP00000004913annotation not available (165 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa)
Psmb9Proteasome subunit beta. (219 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Tubb4aTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
Ccnb2G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (384 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psme1Proteasome activator complex subunit 1. (249 aa)
Psme2Proteasome activator complex subunit 2. (239 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (530 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (308 aa)
Plk1Serine/threonine-protein kinase PLK. (602 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (227 aa)
Psmf1Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (320 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (202 aa)
Psme4Proteasome activator complex subunit 4 isoform X3. (1843 aa)
Psmc2Proteasome 26S subunit, ATPase 2. (349 aa)
Tubal3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
LOC101823019Ubiquitin-like. (114 aa)
Psma1Proteasome subunit alpha type. (206 aa)
Psmd526S proteasome non-ATPase regulatory subunit 5. (504 aa)
ENSMAUP00000007160annotation not available (330 aa)
ENSMAUP00000007258annotation not available (117 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
ENSMAUP00000007909annotation not available (237 aa)
Psmb7Proteasome subunit beta. (277 aa)
Psma2Proteasome subunit alpha type. (245 aa)
ENSMAUP00000008492annotation not available (391 aa)
Tuba4aTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Tubb6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
Tubb1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (446 aa)
ENSMAUP00000000935annotation not available (393 aa)
LOC101831620Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ENSMAUP00000019431annotation not available (150 aa)
Psmb5Proteasome subunit beta. (256 aa)
Psma8Proteasome subunit alpha type. (237 aa)
Psmb11Proteasome subunit beta. (280 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.