30 items (Mesocricetus auratus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Your Input:
	ENSMAUP00000018498	annotation not available (86 aa)
	ENSMAUP00000019431	annotation not available (150 aa)
	Matk	Tyrosine-protein kinase. (466 aa)
	Btc	Probetacellulin. (175 aa)
	Rnf41	E3 ubiquitin-protein ligase NRDP1 isoform X2. (317 aa)
	Egfr	Receptor protein-tyrosine kinase. (1207 aa)
	ENSMAUP00000002256	annotation not available (75 aa)
	Kxd1	ubiquitin-60S ribosomal protein L40. (232 aa)
	Rps27a	ubiquitin-40S ribosomal protein S27a. (156 aa)
	LOC101823019	Ubiquitin-like. (114 aa)
	Cdc37	Hsp90 co-chaperone Cdc37. (379 aa)
	ENSMAUP00000007258	annotation not available (117 aa)
	ENSMAUP00000008197	annotation not available (303 aa)
	Nrg2	Pro-neuregulin-2, membrane-bound isoform. (279 aa)
	Cul5	Cullin-5; Belongs to the cullin family. (754 aa)
	Nrg3	Pro-neuregulin-3, membrane-bound isoform. (676 aa)
	Ptpn18	Tyrosine-protein phosphatase non-receptor type 18. (196 aa)
	Erbin	Erbin isoform X3. (1404 aa)
	Akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	Ereg	Proepiregulin. (162 aa)
	Nrg4	Pro-neuregulin-4, membrane-bound isoform. (115 aa)
	Egf	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (254 aa)
	ENSMAUP00000022314	annotation not available (101 aa)
	Usp8	Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1070 aa)
	Stub1	E3 ubiquitin-protein ligase CHIP isoform X1. (303 aa)
	Akt2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	Erbb2	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...] (1247 aa)
	Erbb4	Receptor protein-tyrosine kinase. (1308 aa)
	Nrg1	Pro-neuregulin-1, membrane-bound isoform. (655 aa)
	Akt3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Akt1	Akt2	ENSMAUP00000012829	ENSMAUP00000023813	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.962
Akt1	Akt3	ENSMAUP00000012829	ENSMAUP00000017298	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.905
Akt1	Cdc37	ENSMAUP00000012829	ENSMAUP00000006582	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Hsp90 co-chaperone Cdc37.	0.960
Akt1	ENSMAUP00000008197	ENSMAUP00000012829	ENSMAUP00000008197	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	annotation not available	0.625
Akt1	Egf	ENSMAUP00000012829	ENSMAUP00000016311	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.646
Akt1	Egfr	ENSMAUP00000012829	ENSMAUP00000000794	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.592
Akt1	Erbb2	ENSMAUP00000012829	ENSMAUP00000024426	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	0.464
Akt1	Erbb4	ENSMAUP00000012829	ENSMAUP00000024513	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.509
Akt1	Matk	ENSMAUP00000012829	ENSMAUP00000022227	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.643
Akt1	Nrg1	ENSMAUP00000012829	ENSMAUP00000025727	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Pro-neuregulin-1, membrane-bound isoform.	0.436
Akt1	Rnf41	ENSMAUP00000012829	ENSMAUP00000000601	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase NRDP1 isoform X2.	0.406
Akt1	Stub1	ENSMAUP00000012829	ENSMAUP00000023738	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase CHIP isoform X1.	0.625
Akt1	Usp8	ENSMAUP00000012829	ENSMAUP00000022621	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family.	0.695
Akt2	Akt1	ENSMAUP00000023813	ENSMAUP00000012829	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.962
Akt2	Akt3	ENSMAUP00000023813	ENSMAUP00000017298	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.889
Akt2	Cdc37	ENSMAUP00000023813	ENSMAUP00000006582	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Hsp90 co-chaperone Cdc37.	0.919
Akt2	ENSMAUP00000008197	ENSMAUP00000023813	ENSMAUP00000008197	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	annotation not available	0.504
Akt2	Egfr	ENSMAUP00000023813	ENSMAUP00000000794	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.611
Akt2	Erbb2	ENSMAUP00000023813	ENSMAUP00000024426	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]	0.514
Akt2	Erbb4	ENSMAUP00000023813	ENSMAUP00000024513	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.468

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