STRINGSTRING
Itch Itch Psmd13 Psmd13 Tal1 Tal1 ENSMAUP00000002256 ENSMAUP00000002256 Kxd1 Kxd1 Psmb8 Psmb8 Lmo3 Lmo3 ENSMAUP00000004913 ENSMAUP00000004913 Lmo2 Lmo2 Gata2 Gata2 Psmc3 Psmc3 Psmb9 Psmb9 Psmc6 Psmc6 Rps27a Rps27a Psmc2 Psmc2 LOC101823019 LOC101823019 Psma1 Psma1 Psmd5 Psmd5 Spi1 Spi1 ENSMAUP00000007193 ENSMAUP00000007193 ENSMAUP00000007258 ENSMAUP00000007258 Psmc4 Psmc4 Myb Myb ENSMAUP00000007909 ENSMAUP00000007909 Psmb7 Psmb7 Psma2 Psma2 Tp73 Tp73 Psma4 Psma4 Psma7 Psma7 Psme4 Psme4 Psmd9 Psmd9 Psmd7 Psmd7 Psmd6 Psmd6 Spib Spib Psmf1 Psmf1 Psmd10 Psmd10 Psmc5 Psmc5 Psmd12 Psmd12 Runx1 Runx1 Psmd14 Psmd14 Cdk7 Cdk7 Psmd3 Psmd3 Psmd2 Psmd2 Psme2 Psme2 Psme1 Psme1 Psmb4 Psmb4 Psme3 Psme3 ENSMAUP00000016290 ENSMAUP00000016290 Psmb1 Psmb1 Tcf3 Tcf3 Gata3 Gata3 Psmd1 Psmd1 Runx1-2 Runx1-2 Psmb11 Psmb11 Psma8 Psma8 Cbfb Cbfb Ccnh Ccnh Psmb5 Psmb5 ENSMAUP00000019431 ENSMAUP00000019431 ENSMAUP00000020392 ENSMAUP00000020392 Ldb1 Ldb1 Mnat1 Mnat1 Psmd8 Psmd8 Psmd11 Psmd11 Psmb3 Psmb3 Psma5 Psma5 Psmc1 Psmc1 ENSMAUP00000022314 ENSMAUP00000022314 Psmd4 Psmd4 Ldb2 Ldb2 Psma6 Psma6 ENSMAUP00000022538 ENSMAUP00000022538 Psmb6 Psmb6 Gata1 Gata1 Psma3 Psma3 Lmo1 Lmo1 Kmt2a Kmt2a Psmb2 Psmb2 ENSMAUP00000025330 ENSMAUP00000025330
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ItchE3 ubiquitin-protein ligase. (841 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
Tal1T-cell acute lymphocytic leukemia protein 1. (183 aa)
ENSMAUP00000002256annotation not available (75 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Psmb8Proteasome subunit beta. (276 aa)
Lmo3LIM domain only protein 3 isoform X1. (156 aa)
ENSMAUP00000004913annotation not available (165 aa)
Lmo2Rhombotin-2 isoform X1. (220 aa)
Gata2Endothelial transcription factor GATA-2. (480 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa)
Psmb9Proteasome subunit beta. (219 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Psmc2Proteasome 26S subunit, ATPase 2. (349 aa)
LOC101823019Ubiquitin-like. (114 aa)
Psma1Proteasome subunit alpha type. (206 aa)
Psmd526S proteasome non-ATPase regulatory subunit 5. (504 aa)
Spi1Transcription factor PU.1 isoform X1. (273 aa)
ENSMAUP00000007193annotation not available (369 aa)
ENSMAUP00000007258annotation not available (117 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
MybTranscriptional activator Myb isoform X1. (760 aa)
ENSMAUP00000007909annotation not available (237 aa)
Psmb7Proteasome subunit beta. (277 aa)
Psma2Proteasome subunit alpha type. (245 aa)
Tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (286 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Psma7Proteasome subunit alpha type. (145 aa)
Psme4Proteasome activator complex subunit 4 isoform X3. (1843 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (202 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (320 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
SpibTranscription factor Spi-B isoform X1. (279 aa)
Psmf1Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (227 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (308 aa)
Runx1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (68 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Cdk7Cyclin dependent kinase 7. (224 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (530 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa)
Psme2Proteasome activator complex subunit 2. (239 aa)
Psme1Proteasome activator complex subunit 1. (249 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psme3Proteasome activator complex subunit 3. (254 aa)
ENSMAUP00000016290annotation not available (246 aa)
Psmb1Proteasome subunit beta. (240 aa)
Tcf3Transcription factor E2-alpha; Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region (By similarity). (633 aa)
Gata3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (443 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
Runx1-2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (62 aa)
Psmb11Proteasome subunit beta. (280 aa)
Psma8Proteasome subunit alpha type. (237 aa)
CbfbCore-binding factor subunit beta isoform X2. (182 aa)
Ccnhcyclin-H; Belongs to the cyclin family. (324 aa)
Psmb5Proteasome subunit beta. (256 aa)
ENSMAUP00000019431annotation not available (150 aa)
ENSMAUP00000020392annotation not available (68 aa)
Ldb1LIM domain-binding protein 1 isoform X1. (398 aa)
Mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (228 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (180 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (419 aa)
Psmb3Proteasome subunit beta. (202 aa)
Psma5Proteasome subunit alpha type. (241 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa)
ENSMAUP00000022314annotation not available (101 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa)
Ldb2LIM domain-binding protein 2 isoform X1. (373 aa)
Psma6Proteasome subunit alpha type. (246 aa)
ENSMAUP00000022538annotation not available (95 aa)
Psmb6Proteasome subunit beta. (238 aa)
Gata1Erythroid transcription factor. (413 aa)
Psma3Proteasome subunit alpha type. (180 aa)
Lmo1Rhombotin-1. (158 aa)
Kmt2aHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3946 aa)
Psmb2Proteasome subunit beta. (201 aa)
ENSMAUP00000025330annotation not available (154 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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