STRINGSTRING
Auts2 Auts2 Csnk2b Csnk2b Smarcb1 Smarcb1 Smarcd2 Smarcd2 ENSMAUP00000023741 ENSMAUP00000023741 Smarca4 Smarca4 ENSMAUP00000023105 ENSMAUP00000023105 Smarcd1 Smarcd1 Actl6a Actl6a Cbx8 Cbx8 Arid1b Arid1b Cbfb Cbfb Runx1-2 Runx1-2 ENSMAUP00000015165 ENSMAUP00000015165 Runx1 Runx1 Cbx4 Cbx4 Cbx2 Cbx2 Smarcd3 Smarcd3 Bmi1 Bmi1 Ring1 Ring1 Hipk2 Hipk2 Phc2 Phc2 Rybp Rybp Arid2 Arid2 Smarca2 Smarca2 Scmh1 Scmh1 Smarcc2 Smarcc2 Pbrm1 Pbrm1 Ep300 Ep300 Arid1a Arid1a LOC106023108 LOC106023108 Smarce1 Smarce1 Pcgf5 Pcgf5 Smarcc1 Smarcc1 Rnf2 Rnf2 Csnk2a2 Csnk2a2 Actl6b Actl6b ENSMAUP00000006748 ENSMAUP00000006748 ENSMAUP00000007021 ENSMAUP00000007021 Yaf2 Yaf2 Csnk2a1 Csnk2a1 Cbx7 Cbx7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Auts2Autism susceptibility gene 2 protein. (983 aa)
Csnk2bCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
Smarcb1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
Smarcd2SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2. (533 aa)
ENSMAUP00000023741annotation not available (119 aa)
Smarca4Transcription activator BRG1 isoform X3. (1646 aa)
ENSMAUP00000023105annotation not available (135 aa)
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
Actl6aActin like 6A. (204 aa)
Cbx8Chromobox protein homolog 8 isoform X1. (366 aa)
Arid1bAT-rich interactive domain-containing protein 1B. (1755 aa)
CbfbCore-binding factor subunit beta isoform X2. (182 aa)
Runx1-2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (62 aa)
ENSMAUP00000015165annotation not available (67 aa)
Runx1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (68 aa)
Cbx4E3 SUMO-protein ligase CBX4. (543 aa)
Cbx2Chromobox protein homolog 2. (518 aa)
Smarcd3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
Bmi1Polycomb complex protein BMI-1. (324 aa)
Ring1E3 ubiquitin-protein ligase RING1 isoform X1. (408 aa)
Hipk2Homeodomain-interacting protein kinase 2; Serine/threonine-protein kinase involved in transcription regulation, p53/TP53-mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1/Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53/TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53/TP53 both at the transcription level and at the protein level (by phosphorylation and indirect [...] (1180 aa)
Phc2Polyhomeotic-like protein 2 isoform X1. (323 aa)
RybpRING1 and YY1-binding protein. (224 aa)
Arid2AT-rich interactive domain-containing protein 2. (1766 aa)
Smarca2Probable global transcription activator SNF2L2. (279 aa)
Scmh1Polycomb protein SCMH1 isoform X1. (664 aa)
Smarcc2SWI/SNF complex subunit SMARCC2. (1052 aa)
Pbrm1Protein polybromo-1. (374 aa)
Ep300Histone acetyltransferase p300 isoform X3. (2417 aa)
Arid1aAT-rich interactive domain-containing protein 1A. (1017 aa)
LOC106023108Polyhomeotic-like protein 1. (41 aa)
Smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
Pcgf5Polycomb group RING finger protein 5 isoform X1. (256 aa)
Smarcc1SWI/SNF complex subunit SMARCC1 isoform X1. (1013 aa)
Rnf2Ring finger protein 2. (218 aa)
Csnk2a2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (325 aa)
Actl6bActin-like protein 6B; Belongs to the actin family. (426 aa)
ENSMAUP00000006748annotation not available (119 aa)
ENSMAUP00000007021annotation not available (68 aa)
Yaf2YY1-associated factor 2. (176 aa)
Csnk2a1LOW QUALITY PROTEIN: casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (380 aa)
Cbx7LOW QUALITY PROTEIN: chromobox protein homolog 7. (254 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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