STRINGSTRING
ENSMAUP00000022538 ENSMAUP00000022538 Psmb6 Psmb6 Psma3 Psma3 ENSMAUP00000002256 ENSMAUP00000002256 Fndc3b Fndc3b Psmd13 Psmd13 Smurf1 Smurf1 Psmb2 Psmb2 MDM2 MDM2 Psmb8 Psmb8 Tgfb1 Tgfb1 Ep300 Ep300 ENSMAUP00000004913 ENSMAUP00000004913 Psmc3 Psmc3 Psmb9 Psmb9 Psmc6 Psmc6 Rps27a Rps27a Psmc2 Psmc2 LOC101823019 LOC101823019 Psma1 Psma1 Psmd5 Psmd5 ENSMAUP00000007258 ENSMAUP00000007258 LOC101827110 LOC101827110 Psmc4 Psmc4 ENSMAUP00000007909 ENSMAUP00000007909 Psmb7 Psmb7 Psma2 Psma2 Src Src Runx3 Runx3 Crebzf Crebzf Smurf2 Smurf2 Psma4 Psma4 Psma7 Psma7 Fndc3a Fndc3a Psmd9 Psmd9 Psmd7 Psmd7 Psmd6 Psmd6 Psmf1 Psmf1 Psmd10 Psmd10 Psmc5 Psmc5 Psmd12 Psmd12 Psmd14 Psmd14 Psmd3 Psmd3 Psmd2 Psmd2 Psme2 Psme2 Psme1 Psme1 Psmb4 Psmb4 Psme3 Psme3 ENSMAUP00000016290 ENSMAUP00000016290 Psmb1 Psmb1 Psmd1 Psmd1 Cbfb Cbfb Psmb5 Psmb5 ENSMAUP00000019431 ENSMAUP00000019431 ENSMAUP00000020392 ENSMAUP00000020392 Psmd8 Psmd8 Psmd11 Psmd11 Psmb3 Psmb3 Kxd1 Kxd1 Psma5 Psma5 Psmc1 Psmc1 ENSMAUP00000022314 ENSMAUP00000022314 Psmd4 Psmd4 Psma6 Psma6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAUP00000022538annotation not available (95 aa)
Psmb6Proteasome subunit beta. (238 aa)
Psma3Proteasome subunit alpha type. (180 aa)
ENSMAUP00000002256annotation not available (75 aa)
Fndc3bFibronectin type III domain-containing protein 3B isoform X1. (1206 aa)
Psmd1326S proteasome non-ATPase regulatory subunit 13. (369 aa)
Smurf1E3 ubiquitin-protein ligase. (679 aa)
Psmb2Proteasome subunit beta. (201 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (270 aa)
Psmb8Proteasome subunit beta. (276 aa)
Tgfb1Transforming growth factor beta-1. (286 aa)
Ep300Histone acetyltransferase p300 isoform X3. (2417 aa)
ENSMAUP00000004913annotation not available (165 aa)
Psmc326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (444 aa)
Psmb9Proteasome subunit beta. (219 aa)
Psmc626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (402 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
Psmc2Proteasome 26S subunit, ATPase 2. (349 aa)
LOC101823019Ubiquitin-like. (114 aa)
Psma1Proteasome subunit alpha type. (206 aa)
Psmd526S proteasome non-ATPase regulatory subunit 5. (504 aa)
ENSMAUP00000007258annotation not available (117 aa)
LOC101827110Fibronectin type III domain containing protein 3C1-like. (1355 aa)
Psmc426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
ENSMAUP00000007909annotation not available (237 aa)
Psmb7Proteasome subunit beta. (277 aa)
Psma2Proteasome subunit alpha type. (245 aa)
SrcTyrosine-protein kinase. (536 aa)
Runx3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (420 aa)
CrebzfCREB/ATF bZIP transcription factor isoform X2. (356 aa)
Smurf2E3 ubiquitin-protein ligase. (67 aa)
Psma4Proteasome subunit alpha type. (261 aa)
Psma7Proteasome subunit alpha type. (145 aa)
Fndc3aFibronectin type-III domain-containing protein 3A. (1171 aa)
Psmd926S proteasome non-ATPase regulatory subunit 9. (202 aa)
Psmd726S proteasome non-ATPase regulatory subunit 7. (320 aa)
Psmd626S proteasome non-ATPase regulatory subunit 6. (389 aa)
Psmf1Proteasome inhibitor PI31 subunit isoform X1. (271 aa)
Psmd1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (227 aa)
Psmc526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
Psmd1226S proteasome non-ATPase regulatory subunit 12. (308 aa)
Psmd1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
Psmd326S proteasome non-ATPase regulatory subunit 3. (530 aa)
Psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (518 aa)
Psme2Proteasome activator complex subunit 2. (239 aa)
Psme1Proteasome activator complex subunit 1. (249 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
Psme3Proteasome activator complex subunit 3. (254 aa)
ENSMAUP00000016290annotation not available (246 aa)
Psmb1Proteasome subunit beta. (240 aa)
Psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
CbfbCore-binding factor subunit beta isoform X2. (182 aa)
Psmb5Proteasome subunit beta. (256 aa)
ENSMAUP00000019431annotation not available (150 aa)
ENSMAUP00000020392annotation not available (68 aa)
Psmd826S proteasome non-ATPase regulatory subunit 8. (180 aa)
Psmd1126S proteasome non-ATPase regulatory subunit 11. (419 aa)
Psmb3Proteasome subunit beta. (202 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Psma5Proteasome subunit alpha type. (241 aa)
Psmc126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (227 aa)
ENSMAUP00000022314annotation not available (101 aa)
Psmd426S proteasome non-ATPase regulatory subunit 4 isoform X1. (371 aa)
Psma6Proteasome subunit alpha type. (246 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.