39 items (Mesocricetus auratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Egf	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (254 aa)
	Notch3	Neurogenic locus notch homolog protein 3. (2268 aa)
	Heyl	Hairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa)
	Dll4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (686 aa)
	LOC101841995	Gamma-secretase subunit APH-1B. (118 aa)
	Ncstn	Nicastrin. (709 aa)
	Pbx1	pre-B-cell leukemia transcription factor 1 isoform X1. (430 aa)
	ENSMAUP00000022314	annotation not available (101 aa)
	Hes5	Transcription factor HES-5. (166 aa)
	Hey1	Hairy/enhancer-of-split related with YRPW motif protein 1. (278 aa)
	ENSMAUP00000019431	annotation not available (150 aa)
	Neurl1a	E3 ubiquitin-protein ligase NEURL1. (541 aa)
	Ptcra	Pre T-cell antigen receptor alpha. (201 aa)
	ENSMAUP00000018639	annotation not available (86 aa)
	Ybx1	Nuclease-sensitive element-binding protein 1. (303 aa)
	Ikzf1	DNA-binding protein Ikaros isoform X1. (539 aa)
	Jag1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	Dlgap5	Disks large-associated protein 5 isoform X2. (787 aa)
	ENSMAUP00000015922	annotation not available (54 aa)
	Adam10	Disintegrin and metalloproteinase domain-containing protein 10. (749 aa)
	Psen2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
	Wwp2	E3 ubiquitin-protein ligase. (431 aa)
	Mib1	E3 ubiquitin-protein ligase MIB1 isoform X1. (1006 aa)
	Hes1	Transcription factor HES-1. (281 aa)
	Dll1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (733 aa)
	Maml2	Mastermind-like protein 2. (968 aa)
	Psenen	Gamma-secretase subunit PEN-2. (101 aa)
	Hey2	Hairy/enhancer-of-split related with YRPW motif protein 2. (337 aa)
	Neurl1b	E3 ubiquitin-protein ligase NEURL1B. (546 aa)
	Aph1a	Gamma-secretase subunit APH-1A. (265 aa)
	Tacc3	Transforming acidic coiled-coil-containing protein 3 isoform X2. (551 aa)
	LOC101823019	Ubiquitin-like. (114 aa)
	Rps27a	ubiquitin-40S ribosomal protein S27a. (156 aa)
	Psen1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	Pbx2	pre-B-cell leukemia transcription factor 2. (430 aa)
	Kxd1	ubiquitin-60S ribosomal protein L40. (232 aa)
	Jag2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1225 aa)
	Pbx4	pre-B-cell leukemia transcription factor 4 isoform X5. (380 aa)
	Egfr	Receptor protein-tyrosine kinase. (1207 aa)

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adam10	Aph1a	ENSMAUP00000015423	ENSMAUP00000007303	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1A.	0.504
Adam10	Dll1	ENSMAUP00000015423	ENSMAUP00000012278	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.764
Adam10	Dll4	ENSMAUP00000015423	ENSMAUP00000024594	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.673
Adam10	Egf	ENSMAUP00000015423	ENSMAUP00000016311	Disintegrin and metalloproteinase domain-containing protein 10.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.477
Adam10	Jag1	ENSMAUP00000015423	ENSMAUP00000016186	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.678
Adam10	Jag2	ENSMAUP00000015423	ENSMAUP00000002760	Disintegrin and metalloproteinase domain-containing protein 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.678
Adam10	LOC101841995	ENSMAUP00000015423	ENSMAUP00000023801	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit APH-1B.	0.406
Adam10	Ncstn	ENSMAUP00000015423	ENSMAUP00000022456	Disintegrin and metalloproteinase domain-containing protein 10.	Nicastrin.	0.673
Adam10	Notch3	ENSMAUP00000015423	ENSMAUP00000025405	Disintegrin and metalloproteinase domain-containing protein 10.	Neurogenic locus notch homolog protein 3.	0.648
Adam10	Psen1	ENSMAUP00000015423	ENSMAUP00000003621	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.609
Adam10	Psen2	ENSMAUP00000015423	ENSMAUP00000015058	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.515
Adam10	Psenen	ENSMAUP00000015423	ENSMAUP00000010771	Disintegrin and metalloproteinase domain-containing protein 10.	Gamma-secretase subunit PEN-2.	0.650
Aph1a	Adam10	ENSMAUP00000007303	ENSMAUP00000015423	Gamma-secretase subunit APH-1A.	Disintegrin and metalloproteinase domain-containing protein 10.	0.504
Aph1a	Dll1	ENSMAUP00000007303	ENSMAUP00000012278	Gamma-secretase subunit APH-1A.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.441
Aph1a	Dll4	ENSMAUP00000007303	ENSMAUP00000024594	Gamma-secretase subunit APH-1A.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.433
Aph1a	Jag1	ENSMAUP00000007303	ENSMAUP00000016186	Gamma-secretase subunit APH-1A.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.457
Aph1a	Jag2	ENSMAUP00000007303	ENSMAUP00000002760	Gamma-secretase subunit APH-1A.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.442
Aph1a	LOC101841995	ENSMAUP00000007303	ENSMAUP00000023801	Gamma-secretase subunit APH-1A.	Gamma-secretase subunit APH-1B.	0.897
Aph1a	Ncstn	ENSMAUP00000007303	ENSMAUP00000022456	Gamma-secretase subunit APH-1A.	Nicastrin.	0.999
Aph1a	Notch3	ENSMAUP00000007303	ENSMAUP00000025405	Gamma-secretase subunit APH-1A.	Neurogenic locus notch homolog protein 3.	0.896

page 1 of 20

Server load: low (28%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About