STRINGSTRING
Dll4 Dll4 Notch3 Notch3 Kxd1 Kxd1 Psen1 Psen1 Rps27a Rps27a LOC101823019 LOC101823019 Egfr Egfr Tacc3 Tacc3 Aph1a Aph1a Neurl1b Neurl1b Psenen Psenen Dll1 Dll1 Mib1 Mib1 Wwp2 Wwp2 Psen2 Psen2 Adam10 Adam10 Jag1 Jag1 Egf Egf Ybx1 Ybx1 Neurl1a Neurl1a ENSMAUP00000019431 ENSMAUP00000019431 ENSMAUP00000022314 ENSMAUP00000022314 Ncstn Ncstn Jag2 Jag2 LOC101841995 LOC101841995
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dll4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (686 aa)
Notch3Neurogenic locus notch homolog protein 3. (2268 aa)
Kxd1ubiquitin-60S ribosomal protein L40. (232 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
Rps27aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC101823019Ubiquitin-like. (114 aa)
EgfrReceptor protein-tyrosine kinase. (1207 aa)
Tacc3Transforming acidic coiled-coil-containing protein 3 isoform X2. (551 aa)
Aph1aGamma-secretase subunit APH-1A. (265 aa)
Neurl1bE3 ubiquitin-protein ligase NEURL1B. (546 aa)
PsenenGamma-secretase subunit PEN-2. (101 aa)
Dll1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (733 aa)
Mib1E3 ubiquitin-protein ligase MIB1 isoform X1. (1006 aa)
Wwp2E3 ubiquitin-protein ligase. (431 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
Adam10Disintegrin and metalloproteinase domain-containing protein 10. (749 aa)
Jag1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (254 aa)
Ybx1Nuclease-sensitive element-binding protein 1. (303 aa)
Neurl1aE3 ubiquitin-protein ligase NEURL1. (541 aa)
ENSMAUP00000019431annotation not available (150 aa)
ENSMAUP00000022314annotation not available (101 aa)
NcstnNicastrin. (709 aa)
Jag2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1225 aa)
LOC101841995Gamma-secretase subunit APH-1B. (118 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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