STRINGSTRING
Slc8a2 Slc8a2 Sphk1 Sphk1 Tnnc2 Tnnc2 Cd38 Cd38 Gna14 Gna14 Gnaq Gnaq F2r F2r Gpr150 Gpr150 Zranb2 Zranb2 LOC110340582 LOC110340582 Pdgfb Pdgfb Ptger3 Ptger3 Mylk4 Mylk4 Agtr1 Agtr1 Htr6 Htr6 Mylk3 Mylk3 Osbpl9 Osbpl9 Htr5b Htr5b Drd1 Drd1 Calm3 Calm3 Otop1 Otop1 Atp2a1 Atp2a1 ENSMAUP00000010883 ENSMAUP00000010883 Gnal Gnal Mylk2 Mylk2 Adcy1 Adcy1 Htr2a Htr2a P2rx2 P2rx2 Pdgfrb Pdgfrb Ppp3ca Ppp3ca ENSMAUP00000011880 ENSMAUP00000011880 Lrrn4cl Lrrn4cl Slc8a3 Slc8a3 Slc25a31 Slc25a31 Ptger1 Ptger1 Plcb4 Plcb4 Bscl2 Bscl2 Itpr2 Itpr2 Pdgfd Pdgfd Chrm1 Chrm1 Adra1b Adra1b Prkcb Prkcb Atp2c1 Atp2c1 Itpkb Itpkb Itpkc Itpkc Stim1 Stim1 Pde1c Pde1c Camk2d Camk2d Ptgfr Ptgfr LOC101834284 LOC101834284 Slc8a1 Slc8a1 Adcy2 Adcy2 Adcy8 Adcy8 P2rx3 P2rx3 Ppp3r1 Ppp3r1 Atp2c2 Atp2c2 Ednrb Ednrb ENSMAUP00000015439 ENSMAUP00000015439 Tpcn1 Tpcn1 Calml4 Calml4 Htr2b Htr2b Pdgfc Pdgfc Tbxa2r Tbxa2r Plcb1 Plcb1 Grin2d Grin2d Cacna1g Cacna1g Egf Egf Adora2a Adora2a Adcy9 Adcy9 Orai1 Orai1 ENSMAUP00000017208 ENSMAUP00000017208 Cysltr1 Cysltr1 Nos2 Nos2 Ryr1 Ryr1 Gna15 Gna15 Ednra Ednra Phkb Phkb Tacr1 Tacr1 Qrfpr Qrfpr Nos1 Nos1 Nos3 Nos3 Itpr1 Itpr1 ENSMAUP00000018538 ENSMAUP00000018538 ENSMAUP00000018578 ENSMAUP00000018578 LOC101840244 LOC101840244 Cxcr4 Cxcr4 Adrb2 Adrb2 Cacna1h Cacna1h Pnck Pnck ENSMAUP00000019352 ENSMAUP00000019352 ENSMAUP00000019393 ENSMAUP00000019393 Cckbr Cckbr Ntsr1 Ntsr1 Tnnc1 Tnnc1 Cacna1c Cacna1c Tpcn2 Tpcn2 Stim2 Stim2 Trhr2 Trhr2 Fbxo21 Fbxo21 ENSMAUP00000020463 ENSMAUP00000020463 Pde1a Pde1a Gnas Gnas Ttn Ttn Slc25a4 Slc25a4 Ptk2b Ptk2b Hrc Hrc Pdgfra Pdgfra Mcoln3 Mcoln3 ENSMAUP00000021198 ENSMAUP00000021198 Pde1b Pde1b Adra1a Adra1a Ptrhd1 Ptrhd1 Adcy3 Adcy3 Calm2 Calm2 Grin2c Grin2c Ppif Ppif Adrb3 Adrb3 Camk2b Camk2b Grin1 Grin1 Camk2a Camk2a Itpr3 Itpr3 ENSMAUP00000022689 ENSMAUP00000022689 Grpr Grpr Cacna1d Cacna1d Pskh1 Pskh1 Oxtr Oxtr Cckar Cckar Plcz1 Plcz1 Camk4 Camk4 ENSMAUP00000024144 ENSMAUP00000024144 Camkv Camkv Chrm5 Chrm5 Erbb2 Erbb2 Mcu Mcu Mcoln1 Mcoln1 Erbb4 Erbb4 Atp2a2 Atp2a2 Cacna1f Cacna1f Asph Asph Pdgfa Pdgfa Ryr3 Ryr3 Ryr2 Ryr2 LOC110341725 LOC110341725 Efcab3 Efcab3 Rcsd1 Rcsd1 LOC106021121 LOC106021121 Cacna1e Cacna1e Catsper4 Catsper4 Calm1 Calm1 Prkacb Prkacb ENSMAUP00000002714 ENSMAUP00000002714 Ppp3r2 Ppp3r2 P2rx4 P2rx4 LOC106021192 LOC106021192 Adora2b Adora2b ENSMAUP00000002428 ENSMAUP00000002428 Htr5a Htr5a Casq1 Casq1 Phka2 Phka2 Plcg1 Plcg1 Prkcg Prkcg Bdkrb2 Bdkrb2 Plcd3 Plcd3 Grm5 Grm5 Plcd4 Plcd4 LOC101841110 LOC101841110 Phkg1 Phkg1 Adcy4 Adcy4 Camk1g Camk1g Stk33 Stk33 Avpr1b Avpr1b Ppp3cc Ppp3cc Egfr Egfr LOC106022989 LOC106022989 Casq2 Casq2 Arsi Arsi Mcub Mcub Plce1 Plce1 Chrm2 Chrm2 Camk1d Camk1d Grm1 Grm1 Mylk Mylk Itpka Itpka Gna11 Gna11 Tacr3 Tacr3 Ppp3cb Ppp3cb Calml3 Calml3 Cacna1s Cacna1s ENSMAUP00000004122 ENSMAUP00000004122 Prkaca Prkaca Camk2g Camk2g Chrna7 Chrna7 Adcy7 Adcy7 Atp2a3 Atp2a3 Htr4 Htr4 Ltb4r2 Ltb4r2 Plcb2 Plcb2 Mcoln2 Mcoln2 Vdac2 Vdac2 Chrm3 Chrm3 Lhcgr Lhcgr P2rx6 P2rx6 Camk1 Camk1 Plcg2 Plcg2 Atp2b4 Atp2b4 Pln Pln Ighm Ighm Hrh2 Hrh2 ENSMAUP00000006097 ENSMAUP00000006097 Lyl1 Lyl1 Vps35 Vps35 Tacr2 Tacr2 Sphk2 Sphk2 Orai2 Orai2 Htr7 Htr7 Plcd1 Plcd1 P2rx5 P2rx5 Cacna1b Cacna1b Cysltr2 Cysltr2 Drd5 Drd5 Phka1 Phka1 Prkca Prkca Ptafr Ptafr Cacna1i Cacna1i Adra1d Adra1d Phkg2 Phkg2 Atp2b1 Atp2b1 Atp2b2 Atp2b2 Grin2a Grin2a Htr2c Htr2c Orai3 Orai3 Hrh1 Hrh1 Trhr Trhr Atp2b3 Atp2b3 P2rx1 P2rx1 Vdac3 Vdac3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Slc8a2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
Sphk1Sphingosine kinase 1 isoform X2. (382 aa)
Tnnc2Troponin C, skeletal muscle. (160 aa)
Cd38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (300 aa)
Gna14Guanine nucleotide-binding protein subunit alpha-14 isoform X1. (355 aa)
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
F2rProteinase-activated receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
Gpr150Probable G-protein coupled receptor 150. (427 aa)
Zranb2Zinc finger Ran-binding domain-containing protein 2; May interfere with constitutive 5'-splice site selection. Belongs to the ZRANB2 family. (330 aa)
LOC110340582Uncharacterized protein LOC110340582. (143 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (221 aa)
Ptger3Prostaglandin E2 receptor EP3 subtype. (366 aa)
Mylk4Myosin light chain kinase family member 4. (404 aa)
Agtr1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Htr65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (438 aa)
Mylk3Myosin light chain kinase 3 isoform X2. (786 aa)
Osbpl9Oxysterol-binding protein; Belongs to the OSBP family. (746 aa)
Htr5b5-hydroxytryptamine receptor 5B. (370 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
Otop1Otopetrin-1. (600 aa)
Atp2a1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (980 aa)
ENSMAUP00000010883annotation not available (214 aa)
GnalGuanine nucleotide-binding protein G(Olf) subunit alpha. (142 aa)
Mylk2Myosin light chain kinase 2, skeletal/cardiac muscle. (703 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1118 aa)
Htr2a5-hydroxytryptamine receptor 2A. (471 aa)
P2rx2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (414 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (703 aa)
Ppp3caSerine/threonine-protein phosphatase. (521 aa)
ENSMAUP00000011880annotation not available (232 aa)
Lrrn4clLRRN4 C-terminal-like protein. (237 aa)
Slc8a3Sodium/calcium exchanger 3 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
Slc25a31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
Ptger1Prostaglandin E2 receptor EP1 subtype. (404 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
Bscl2Seipin isoform X1. (335 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (2584 aa)
PdgfdPlatelet-derived growth factor D. (313 aa)
Chrm1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
Adra1bAlpha-1B adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity); Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily. (515 aa)
PrkcbProtein kinase C beta. (554 aa)
Atp2c1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (953 aa)
ItpkbKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
ItpkcKinase; Belongs to the inositol phosphokinase (IPK) family. (677 aa)
Stim1Stromal interaction molecule 1 isoform X2. (685 aa)
Pde1cPhosphodiesterase. (539 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
PtgfrProstaglandin F2-alpha receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
Slc8a1Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (970 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
P2rx3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
Ppp3r1Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (157 aa)
Atp2c2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (944 aa)
EdnrbEndothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (432 aa)
ENSMAUP00000015439annotation not available (155 aa)
Tpcn1Two pore calcium channel protein 1 isoform X2. (822 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
Htr2b5-hydroxytryptamine receptor 2B. (480 aa)
PdgfcPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
Tbxa2rThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (339 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Grin2dGlutamate receptor ionotropic, NMDA 2D. (1251 aa)
Cacna1gVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (385 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (254 aa)
Adora2aAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa)
Adcy9Adenylate cyclase type 9 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
Orai1Calcium release-activated calcium channel protein 1. (302 aa)
ENSMAUP00000017208annotation not available (174 aa)
Cysltr1Cysteinyl leukotriene receptor 1. (347 aa)
Nos2Nitric oxide synthase; Produces nitric oxide (NO). (1156 aa)
Ryr1LOW QUALITY PROTEIN: ryanodine receptor 1. (4094 aa)
Gna15Guanine nucleotide-binding protein subunit alpha-15 isoform X1. (374 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PhkbPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1085 aa)
Tacr1substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
QrfprPyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (433 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (80 aa)
Nos3Nitric oxide synthase; Produces nitric oxide (NO). (1202 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
ENSMAUP00000018538annotation not available (171 aa)
ENSMAUP00000018578annotation not available (119 aa)
LOC101840244type-1A angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Cxcr4C-X-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Adrb2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H isoform X3. (147 aa)
PnckCalcium/calmodulin-dependent protein kinase type 1B isoform X1; Belongs to the protein kinase superfamily. (343 aa)
ENSMAUP00000019352annotation not available (763 aa)
ENSMAUP00000019393annotation not available (70 aa)
CckbrGastrin/cholecystokinin type B receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (451 aa)
Ntsr1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (417 aa)
Tnnc1Troponin C, slow skeletal and cardiac muscles. (161 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
Tpcn2Two pore calcium channel protein 2 isoform X2. (736 aa)
Stim2Stromal interaction molecule 2 isoform X2. (812 aa)
Trhr2Thyrotropin-releasing hormone receptor-like; Belongs to the G-protein coupled receptor 1 family. (382 aa)
Fbxo21F-box only protein 21 isoform X1. (627 aa)
ENSMAUP00000020463annotation not available (168 aa)
Pde1aPhosphodiesterase. (536 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
TtnTitin. (441 aa)
Slc25a4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
HrcSarcoplasmic reticulum histidine-rich calcium-binding protein. (80 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
Mcoln3Mucolipin-3. (488 aa)
ENSMAUP00000021198annotation not available (119 aa)
Pde1bPhosphodiesterase. (535 aa)
Adra1aalpha-1A adrenergic receptor isoform X1. (465 aa)
Ptrhd1LOW QUALITY PROTEIN: putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
Calm2Calmodulin 2. (149 aa)
Grin2cGlutamate receptor ionotropic, NMDA 2C isoform X1. (1237 aa)
PpifPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (206 aa)
Adrb3Beta-3 adrenergic receptor. (404 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X4. (666 aa)
Grin1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
ENSMAUP00000022689annotation not available (268 aa)
GrprGastrin-releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha-1D; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines; B [...] (1378 aa)
Pskh1Serine/threonine-protein kinase H1; Belongs to the protein kinase superfamily. (424 aa)
OxtrOxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (390 aa)
CckarCholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (429 aa)
Plcz1Phosphoinositide phospholipase C. (632 aa)
Camk4Calcium/calmodulin-dependent protein kinase type IV isoform X1; Belongs to the protein kinase superfamily. (466 aa)
ENSMAUP00000024144annotation not available (159 aa)
CamkvcaM kinase-like vesicle-associated protein. (506 aa)
Chrm5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
Erbb2Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...] (1247 aa)
McuCalcium uniporter protein, mitochondrial isoform X1. (350 aa)
Mcoln1Mucolipin-1 isoform X2. (524 aa)
Erbb4Receptor protein-tyrosine kinase. (1308 aa)
Atp2a2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (966 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1979 aa)
AsphAspartyl/asparaginyl beta-hydroxylase isoform X8. (211 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (211 aa)
Ryr3Ryanodine receptor 3. (4846 aa)
Ryr2LOW QUALITY PROTEIN: ryanodine receptor 2. (4881 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
Efcab3EF-hand calcium-binding domain-containing protein 3. (430 aa)
Rcsd1capZ-interacting protein isoform X1. (397 aa)
LOC106021121Uncharacterized protein LOC106021121. (209 aa)
Cacna1eVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2237 aa)
Catsper4Cation channel sperm-associated protein 4. (429 aa)
Calm1Calmodulin 1. (149 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
ENSMAUP00000002714annotation not available (58 aa)
Ppp3r2Calcineurin subunit B type 2. (183 aa)
P2rx4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (151 aa)
LOC106021192ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (248 aa)
Adora2bAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
ENSMAUP00000002428annotation not available (67 aa)
Htr5a5-hydroxytryptamine receptor 5A. (357 aa)
Casq1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (401 aa)
Phka2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1229 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1293 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
Bdkrb2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (394 aa)
Plcd3Phosphoinositide phospholipase C. (785 aa)
Grm5Metabotropic glutamate receptor 5 isoform X1. (1203 aa)
Plcd4Phosphoinositide phospholipase C. (784 aa)
LOC101841110LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like. (321 aa)
Phkg1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (370 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
Camk1gCalcium/calmodulin-dependent protein kinase type 1G isoform X1. (478 aa)
Stk33Serine/threonine-protein kinase 33. (492 aa)
Avpr1bVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa)
Ppp3ccSerine/threonine-protein phosphatase. (514 aa)
EgfrReceptor protein-tyrosine kinase. (1207 aa)
LOC106022989Mucolipin-1-like. (79 aa)
Casq2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (419 aa)
ArsiArylsulfatase I. (573 aa)
McubCalcium uniporter regulatory subunit MCUb, mitochondrial isoform X1. (343 aa)
Plce1Phosphoinositide phospholipase C. (2300 aa)
Chrm2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
Camk1dCalcium/calmodulin-dependent protein kinase type 1D. (284 aa)
Grm1Metabotropic glutamate receptor 1. (829 aa)
MylkMyosin light chain kinase, smooth muscle isoform X1. (1923 aa)
ItpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (459 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
Tacr3neuromedin-K receptor; Belongs to the G-protein coupled receptor 1 family. (452 aa)
Ppp3cbSerine/threonine-protein phosphatase. (483 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
ENSMAUP00000004122annotation not available (116 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3. (559 aa)
Chrna7Neuronal acetylcholine receptor subunit alpha-7. (502 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
Atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1038 aa)
Htr45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (388 aa)
Ltb4r2Leukotriene B4 receptor 2. (358 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
Mcoln2Mucolipin-2 isoform X2. (571 aa)
Vdac2Voltage-dependent anion-selective channel protein 2. (295 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (589 aa)
LhcgrLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (698 aa)
P2rx6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (379 aa)
Camk1Calcium/calmodulin-dependent protein kinase type 1 isoform X1; Belongs to the protein kinase superfamily. (374 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
Atp2b4ATPase plasma membrane Ca2+ transporting 4. (1038 aa)
PlnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
IghmIg mu chain C region. (454 aa)
Hrh2Histamine H2 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (421 aa)
ENSMAUP00000006097annotation not available (76 aa)
Lyl1Voltage-dependent P/Q-type calcium channel subunit alpha-1A. (2248 aa)
Vps35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
Tacr2Substance-K receptor; This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P; Belongs to the G-protein coupled receptor 1 family. (384 aa)
Sphk2Sphingosine kinase 2 isoform X2. (613 aa)
Orai2Protein orai-2. (250 aa)
Htr75-hydroxytryptamine receptor 7 isoform X1; Belongs to the G-protein coupled receptor 1 family. (470 aa)
Plcd1Phosphoinositide phospholipase C. (744 aa)
P2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (205 aa)
Cacna1bVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2331 aa)
Cysltr2Cysteinyl leukotriene receptor 2. (315 aa)
Drd5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (475 aa)
Phka1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1037 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PtafrPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (341 aa)
Cacna1iVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2197 aa)
Adra1dalpha-1D adrenergic receptor. (562 aa)
Phkg2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Belongs to the protein kinase superfamily. (145 aa)
Atp2b1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
Atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
Htr2c5-hydroxytryptamine receptor 2C. (393 aa)
Orai3Protein orai-3. (290 aa)
Hrh1Histamine H1 receptor; Belongs to the G-protein coupled receptor 1 family. (489 aa)
TrhrThyrotropin-releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (317 aa)
Atp2b3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1203 aa)
P2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
Vdac3Voltage-dependent anion-selective channel protein 3 isoform X2. (283 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
Server load: low (18%) [HD]