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| | Foxo1 | Forkhead box protein O1. (633 aa) |
| | Sos1 | Son of sevenless homolog 1. (1319 aa) |
| | Tpte | LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like. (670 aa) |
| | S1pr1 | Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (383 aa) |
| | Egfr | Receptor protein-tyrosine kinase. (1207 aa) |
| | Cdkn1a | Cyclin-dependent kinase inhibitor 1. (163 aa) |
| | Prkaa1 | Non-specific serine/threonine protein kinase. (522 aa) |
| | Cdkn2d | Cyclin-dependent kinase 4 inhibitor D. (166 aa) |
| | Pmepa1 | Protein TMEPAI. (275 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | ENSMAUP00000002088 | annotation not available (129 aa) |
| | Ccnb1 | G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (447 aa) |
| | Skp2 | S-phase kinase-associated protein 2. (354 aa) |
| | G6pc | Glucose-6-phosphatase. (320 aa) |
| | Tgfbr2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | LOC101831400 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa) |
| | Rasl11b | Ras-like protein family member 11B. (247 aa) |
| | Grap | GRB2-related adapter protein isoform X1. (217 aa) |
| | Tssk3 | Testis-specific serine/threonine-protein kinase 3. (268 aa) |
| | Grm1 | Metabotropic glutamate receptor 1. (829 aa) |
| | Tgfb1 | Transforming growth factor beta-1. (286 aa) |
| | Csnk1e | Casein kinase I isoform X2; Belongs to the protein kinase superfamily. (416 aa) |
| | Eras | GTPase ERas. (228 aa) |
| | Ccnb3 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1356 aa) |
| | Ep300 | Histone acetyltransferase p300 isoform X3. (2417 aa) |
| | Rem1 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (297 aa) |
| | Ldlrad4 | Low-density lipoprotein receptor class A domain-containing protein 4 isoform X1. (306 aa) |
| | Tmem232 | Transmembrane protein 232 isoform X1. (681 aa) |
| | Prmt1 | Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa) |
| | Tgfb3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | Pten | Phosphatase and tensin homolog. (403 aa) |
| | Mapk8 | Mitogen-activated protein kinase. (427 aa) |
| | Prkaa2 | Non-specific serine/threonine protein kinase. (542 aa) |
| | Gem | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa) |
| | Pik3cb | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | Agap2 | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 isoform X2. (1186 aa) |
| | Rrad | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (307 aa) |
| | Rasgef1a | ras-GEF domain-containing family member 1A isoform X2. (481 aa) |
| | Fbxo32 | F-box only protein 32. (355 aa) |
| | Suco | SUN domain-containing ossification factor isoform X4. (1254 aa) |
| | Tssk4 | Testis-specific serine/threonine-protein kinase 4. (294 aa) |
| | Faslg | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa) |
| | Pdpk1 | 3-phosphoinositide-dependent protein kinase 1 isoform X2. (559 aa) |
| | Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | Usp7 | Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (496 aa) |
| | Tssk6 | Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (273 aa) |
| | Sirt1 | NAD-dependent protein deacetylase sirtuin-1. (691 aa) |
| | Snapin | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | S1pr4 | Sphingosine 1-phosphate receptor 4. (385 aa) |
| | Plk4 | Serine/threonine-protein kinase PLK4 isoform X1. (927 aa) |
| | Stat3 | Signal transducer and activator of transcription. (758 aa) |
| | Plk5 | Inactive serine/threonine-protein kinase PLK5. (579 aa) |
| | Ccng2 | cyclin-G2; Belongs to the cyclin family. (344 aa) |
| | Prmt8 | Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (386 aa) |
| | Gabarapl1 | Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa) |
| | Plk2 | Serine/threonine-protein kinase PLK. (682 aa) |
| | Il10 | Interleukin-10 isoform X1. (178 aa) |
| | Prkag3 | 5'-AMP-activated protein kinase subunit gamma-3. (481 aa) |
| | Prkag2 | 5'-AMP-activated protein kinase subunit gamma-2 isoform X1. (443 aa) |
| | Foxj3 | Forkhead box protein J3 isoform X2. (606 aa) |
| | Sgk1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (525 aa) |
| | Bcl2l11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (197 aa) |
| | Smad4 | Mothers against decapentaplegic homolog. (552 aa) |
| | Gabarap | GABA type A receptor-associated protein. (97 aa) |
| | Araf | Serine/threonine-protein kinase A-Raf isoform X2. (604 aa) |
| | Klf2 | Krueppel-like factor 2. (355 aa) |
| | Tgfb2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | Irs4 | LOW QUALITY PROTEIN: insulin receptor substrate 4. (1227 aa) |
| | Crebbp | CREB-binding protein. (2433 aa) |
| | Bcl6 | B-cell lymphoma 6 protein. (707 aa) |
| | G6pc3 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa) |
| | Igf1r | Tyrosine-protein kinase receptor. (1154 aa) |
| | Rag1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1041 aa) |
| | Rag2 | V(D)J recombination-activating protein 2. (527 aa) |
| | Homer1 | Homer protein homolog 1. (374 aa) |
| | Map2k1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | Setd7 | SET domain containing 7, histone lysine methyltransferase. (208 aa) |
| | Map2k2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | Prkag1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform X2. (330 aa) |
| | Atm | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3014 aa) |
| | Mapk3 | Mitogen-activated protein kinase. (380 aa) |
| | Prmt3 | Protein arginine N-methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (527 aa) |
| | Rasgef1b | ras-GEF domain-containing family member 1B. (542 aa) |
| | Cat | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | Rnf111 | E3 ubiquitin-protein ligase Arkadia isoform X3. (990 aa) |
| | Gadd45a | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Plk1 | Serine/threonine-protein kinase PLK. (602 aa) |
| | Sos2 | Son of sevenless homolog 2 isoform X1. (1308 aa) |
| | Tgfbr1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | Stk11 | Serine/threonine-protein kinase STK11 isoform X2; Belongs to the protein kinase superfamily. (438 aa) |
| | Pck2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (474 aa) |
| | Foxj2 | Forkhead box protein J2 isoform X4. (563 aa) |
| | Foxo3 | Forkhead box protein O3. (672 aa) |
| | Csde1 | Cold shock domain-containing protein E1 isoform X3. (798 aa) |
| | Homer3 | Homer protein homolog 3 isoform X1. (355 aa) |
| | Cdk3 | Cyclin-dependent kinase 3 isoform X2; Belongs to the protein kinase superfamily. (297 aa) |
| | Tnfsf10 | Tumor necrosis factor ligand superfamily member. (289 aa) |
| | Rnf6 | E3 ubiquitin-protein ligase RNF6. (620 aa) |
| | Homer2 | Homer protein homolog 2 isoform X1. (353 aa) |
| | Fbxo25 | F-box only protein 25 isoform X2. (365 aa) |
| | Rbl2 | Retinoblastoma-like protein 2 isoform X2. (1134 aa) |
| | Irs1 | Insulin receptor substrate 1. (1233 aa) |
| | Ikbkb | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa) |
| | Prkab2 | 5'-AMP-activated protein kinase subunit beta-2 isoform X1. (271 aa) |
| | Gadd45b | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | Raf1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | Egf | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (254 aa) |
| | LOC101833362 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (187 aa) |
| | ENSMAUP00000016715 | annotation not available (418 aa) |
| | Mapk14 | Mitogen-activated protein kinase. (360 aa) |
| | Il7r | Interleukin 7 receptor. (341 aa) |
| | Braf | Serine/threonine-protein kinase B-raf. (710 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Ccnd2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa) |
| | Pik3r2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa) |
| | Slc2a4 | Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (510 aa) |
| | Grb2 | Growth factor receptor-bound protein 2. (217 aa) |
| | Mapk10 | Mitogen-activated protein kinase 10. (252 aa) |
| | Mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa) |
| | Gabarapl2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) |
| | Mapk13 | Mitogen-activated protein kinase. (366 aa) |
| | Mapk9 | Mitogen-activated protein kinase. (423 aa) |
| | Chuk | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa) |
| | Kras | GTPase KRas isoform X3. (189 aa) |
| | Nlk | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa) |
| | Il6 | Interleukin-6. (212 aa) |
| | Atg12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (141 aa) |
| | Ccnd1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | Sgk3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (476 aa) |
| | Ccnb2 | G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (384 aa) |
| | Tssk1b | Testis-specific serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (366 aa) |
| | Tssk2 | Testis-specific serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily. (359 aa) |
| | Plk3 | Serine/threonine-protein kinase PLK. (648 aa) |
| | Cdkn1b | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | Ins | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | Bcl6b | B-cell CLL/lymphoma 6 member B protein. (472 aa) |
| | Foxg1 | Forkhead box protein G1. (484 aa) |
| | Stk4 | Serine/threonine-protein kinase 4. (448 aa) |
| | Cdk2 | Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa) |
| | Tssk5 | Testis-specific serine kinase 5. (322 aa) |
| | Cdkn2b | Cyclin-dependent kinase 4 inhibitor B isoform X1. (130 aa) |
| | Foxo4 | Forkhead box protein O4. (507 aa) |
| | Pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | Nras | NRAS proto-oncogene, GTPase. (98 aa) |
| | Hras | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) |
| | Gadd45g | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | Slc35e3 | Solute carrier family 35 member E3 isoform X1. (313 aa) |
| | Irs2 | Insulin receptor substrate 2. (1333 aa) |
| | Pck1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (623 aa) |
| | Foxo6 | Forkhead box protein O6. (559 aa) |
| | Igf1 | Insulin-like growth factor 1. (153 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Irs3 | Insulin receptor substrate 1-like. (493 aa) |
| | Prkab1 | 5'-AMP-activated protein kinase subunit beta-1. (270 aa) |
| | Pik3r2-2 | Phosphoinositide-3-kinase regulatory subunit 2. (71 aa) |
| | Sod2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) |
| | Rem2 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (341 aa) |
| | Nostrin | Nostrin. (309 aa) |
| | G6pc2 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa) |
| | Mapk12 | Mitogen-activated protein kinase. (367 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (270 aa) |
| | Smad3 | Mothers against decapentaplegic homolog. (425 aa) |
| | Mapk11 | Mitogen-activated protein kinase. (355 aa) |
