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Mapk8 Mapk8 Becn1 Becn1 LOC106021303 LOC106021303 Birc5 Birc5 Ngfr Ngfr Birc7 Birc7 ENSMAUP00000021279 ENSMAUP00000021279 Septin4 Septin4 Casp8 Casp8 Bak1 Bak1 Xiap Xiap Birc2 Birc2 Fadd Fadd Mapk9 Mapk9 Mapk10 Mapk10 Cyct Cyct CUNH17orf47 CUNH17orf47 Birc6 Birc6 Bax Bax Casp9 Casp9 Diablo-2 Diablo-2 Tmem198 Tmem198 ENSMAUP00000012115 ENSMAUP00000012115 ENSMAUP00000011696 ENSMAUP00000011696 Htra2 Htra2 CUNH7orf31 CUNH7orf31 Apaf1 Apaf1 Bbc3 Bbc3 Bcl2l11 Bcl2l11 Tmem198b Tmem198b Casp7 Casp7 Bcl2 Bcl2 Bok Bok Pmaip1 Pmaip1 Diablo Diablo LOC101842058 LOC101842058 ENSMAUP00000001870 ENSMAUP00000001870 Dhdh Dhdh Tnfrsf1a Tnfrsf1a Bcl2l1 Bcl2l1 Casp3 Casp3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Mapk8Mitogen-activated protein kinase. (427 aa)
Becn1Beclin-1 isoform X1. (456 aa)
LOC106021303Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
Birc5Baculoviral IAP repeat-containing protein 5. (142 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (431 aa)
Birc7Baculoviral IAP repeat-containing protein 7. (285 aa)
ENSMAUP00000021279annotation not available (98 aa)
Septin4Septin-4 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (478 aa)
Casp8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa)
Bak1Bcl-2 homologous antagonist/killer. (209 aa)
XiapE3 ubiquitin-protein ligase XIAP. (496 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (592 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
CyctCytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CUNH17orf47Uncharacterized protein C17orf47 homolog. (501 aa)
Birc6Baculoviral IAP repeat-containing protein 6. (4829 aa)
BaxApoptosis regulator BAX isoform X1. (192 aa)
Casp9Caspase-9; Belongs to the peptidase C14A family. (440 aa)
Diablo-2Diablo homolog, mitochondrial. (225 aa)
Tmem198Transmembrane protein 198. (360 aa)
ENSMAUP00000012115annotation not available (87 aa)
ENSMAUP00000011696annotation not available (450 aa)
Htra2Serine protease HTRA2, mitochondrial. (458 aa)
CUNH7orf31Uncharacterized protein C7orf31 homolog isoform X1. (589 aa)
Apaf1Apoptotic protease-activating factor 1. (222 aa)
Bbc3Bcl-2-binding component 3 isoform X2. (193 aa)
Bcl2l11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (197 aa)
Tmem198bLOW QUALITY PROTEIN: transmembrane protein 198-like. (345 aa)
Casp7Caspase-7 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP- ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death (By similarity). (297 aa)
Bcl2Apoptosis regulator Bcl-2. (236 aa)
BokBcl-2-related ovarian killer protein. (213 aa)
Pmaip1Phorbol-12-myristate-13-acetate-induced protein 1. (105 aa)
DiabloDiablo IAP-binding mitochondrial protein. (201 aa)
LOC101842058Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
ENSMAUP00000001870annotation not available (99 aa)
DhdhTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (297 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (468 aa)
Bcl2l1Bcl-2-like protein 1. (233 aa)
Casp3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (246 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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