STRINGSTRING
H2ac1 H2ac1 LOC101835654 LOC101835654 Cyld Cyld Traf5 Traf5 ENSMAUP00000001718 ENSMAUP00000001718 Zbp1 Zbp1 LOC101841110 LOC101841110 Traf2 Traf2 Tmed7 Tmed7 Ripk1 Ripk1 Stat6 Stat6 Tradd Tradd Eif2ak2 Eif2ak2 Aifm1 Aifm1 Lgsn Lgsn Arsi Arsi Hmgb3 Hmgb3 ENSMAUP00000025679 ENSMAUP00000025679 Chmp5 Chmp5 Usp2 Usp2 Jmjd7 Jmjd7 Tlr3 Tlr3 Sntb2 Sntb2 Spata2 Spata2 Vps4a Vps4a Pgpep1 Pgpep1 Stat4 Stat4 Chmp1a Chmp1a Irf9 Irf9 LOC106022166 LOC106022166 Chmp4b Chmp4b ENSMAUP00000022827 ENSMAUP00000022827 LOC106020873 LOC106020873 Nlrp3 Nlrp3 ENSMAUP00000022689 ENSMAUP00000022689 Cflar Cflar Rfwd3 Rfwd3 Camk2a Camk2a Camk2b Camk2b Capn9 Capn9 Hmgb1 Hmgb1 Tnfaip3 Tnfaip3 Cracr2b Cracr2b Trpm7 Trpm7 Glul Glul Ppia Ppia Vps4b Vps4b Sntb1 Sntb1 Slc25a4 Slc25a4 Il1a Il1a Casp8 Casp8 Capn12 Capn12 Hsp90ab1 Hsp90ab1 Ticam1 Ticam1 ENSMAUP00000020297 ENSMAUP00000020297 H1f4 H1f4 H1f2 H1f2 Xiap Xiap Mlkl Mlkl Birc2 Birc2 Rnf31 Rnf31 ENSMAUP00000019710 ENSMAUP00000019710 Ticam2 Ticam2 Tyk2 Tyk2 Chmp7 Chmp7 LOC101822968 LOC101822968 Xkrx Xkrx ENSMAUP00000019352 ENSMAUP00000019352 Fadd Fadd Pygb Pygb Il1b Il1b ENSMAUP00000018818 ENSMAUP00000018818 Mapk9 Mapk9 Pla2g4c Pla2g4c Tlr4 Tlr4 Mapk10 Mapk10 Chmp1b Chmp1b Macroh2a1 Macroh2a1 LOC101837947 LOC101837947 Rbck1 Rbck1 LOC101839247 LOC101839247 Chmp2a Chmp2a Bax Bax Macroh2a2 Macroh2a2 Stat1 Stat1 ENSMAUP00000015122 ENSMAUP00000015122 Glud1 Glud1 Sqstm1 Sqstm1 LOC101824849 LOC101824849 Tnf Tnf Tnfsf10 Tnfsf10 Pygm Pygm ENSMAUP00000014485 ENSMAUP00000014485 Ifnar1 Ifnar1 Snta1 Snta1 Camk2d Camk2d Ifng Ifng Fth1 Fth1 Capn8 Capn8 Hmgb2 Hmgb2 LOC106022112 LOC106022112 ENSMAUP00000013239 ENSMAUP00000013239 Pelp1 Pelp1 ENSMAUP00000012618 ENSMAUP00000012618 Stat2 Stat2 Pygl Pygl Slc25a31 Slc25a31 ENSMAUP00000011880 ENSMAUP00000011880 Capn2 Capn2 LOC110339561 LOC110339561 ENSMAUP00000011696 ENSMAUP00000011696 Spata2l Spata2l Pla2g4e Pla2g4e Tmed3 Tmed3 Pla2g4a Pla2g4a Faf1 Faf1 ENSMAUP00000011068 ENSMAUP00000011068 LOC101834491 LOC101834491 ENSMAUP00000010883 ENSMAUP00000010883 2610002M06Rik 2610002M06Rik Pla2g4d Pla2g4d Bcl2 Bcl2 H2aw H2aw Pla2g4f Pla2g4f Dnm1l Dnm1l Chmp6 Chmp6 Jak3 Jak3 Ppid Ppid Cracr2a Cracr2a Casp1 Casp1 ENSMAUP00000008766 ENSMAUP00000008766 Vdac3 Vdac3 Jak1 Jak1 Il33 Il33 ENSMAUP00000008492 ENSMAUP00000008492 ENSMAUP00000008467 ENSMAUP00000008467 H2ax H2ax ENSMAUP00000007999 ENSMAUP00000007999 Usp21 Usp21 Chmp3 Chmp3 Capn1 Capn1 Pgam5 Pgam5 Fas Fas Ripk3 Ripk3 Stat3 Stat3 Jak2 Jak2 Parp1 Parp1 Ftl Ftl Rnf103 Rnf103 Faslg Faslg Smpd1 Smpd1 Suco Suco Chmp4c Chmp4c Vdac2 Vdac2 Mapk8 Mapk8 Pycard Pycard LOC101842510 LOC101842510 Rab44 Rab44 ENSMAUP00000004541 ENSMAUP00000004541 LOC101835406 LOC101835406 Camk2g Camk2g Ifngr1 Ifngr1 Hmgb4 Hmgb4 H2az2 H2az2 LOC101824534 LOC101824534 Sharpin Sharpin Tnfrsf1a Tnfrsf1a H2aj H2aj LOC106021192 LOC106021192 Dhdh Dhdh Capn11 Capn11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2ac1Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC101835654Signal transducer and activator of transcription. (228 aa)
CyldUbiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (956 aa)
Traf5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (550 aa)
ENSMAUP00000001718annotation not available (115 aa)
Zbp1Z-DNA-binding protein 1 isoform X1. (407 aa)
LOC101841110LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like. (321 aa)
Traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
Tmed7Transmembrane emp24 domain-containing protein 7. (225 aa)
Ripk1Receptor-interacting serine/threonine-protein kinase 1. (658 aa)
Stat6Signal transducer and activator of transcription. (746 aa)
TraddTumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (310 aa)
Eif2ak2Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (517 aa)
Aifm1Apoptosis-inducing factor 1, mitochondrial isoform X1. (612 aa)
LgsnLengsin; Belongs to the glutamine synthetase family. (563 aa)
ArsiArylsulfatase I. (573 aa)
Hmgb3High mobility group protein B3. (200 aa)
ENSMAUP00000025679annotation not available (108 aa)
Chmp5Charged multivesicular body protein 5. (219 aa)
Usp2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (317 aa)
Jmjd7Phospholipase A2. (1015 aa)
Tlr3Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
Sntb2Beta-2-syntrophin. (372 aa)
Spata2Spermatogenesis-associated protein 2. (521 aa)
Vps4aVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (439 aa)
Pgpep1Pyroglutamyl-peptidase 1. (122 aa)
Stat4Signal transducer and activator of transcription. (748 aa)
Chmp1aCharged multivesicular body protein 1a. (196 aa)
Irf9Interferon regulatory factor 9 isoform X1. (390 aa)
LOC106022166Peptidyl-prolyl cis-trans isomerase A-like. (164 aa)
Chmp4bCharged multivesicular body protein 4b. (224 aa)
ENSMAUP00000022827annotation not available (111 aa)
LOC106020873Tumor necrosis factor receptor superfamily member 26-like. (188 aa)
Nlrp3NACHT, LRR and PYD domains-containing protein 3 isoform X1. (1036 aa)
ENSMAUP00000022689annotation not available (268 aa)
CflarCASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (219 aa)
Rfwd3E3 ubiquitin-protein ligase RFWD3 isoform X2. (771 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X4. (666 aa)
Capn9Calpain-9; Belongs to the peptidase C2 family. (680 aa)
Hmgb1High mobility group protein B1. (219 aa)
Tnfaip3Tumor necrosis factor alpha-induced protein 3 isoform X1. (776 aa)
Cracr2bEF-hand calcium-binding domain-containing protein 4A isoform X1. (393 aa)
Trpm7Transient receptor potential cation channel subfamily M member 7. (1756 aa)
GlulGlutamine synthetase. (361 aa)
PpiaPeptidyl-prolyl cis-trans isomerase A. (164 aa)
Vps4bVacuolar protein sorting-associated protein 4B. (387 aa)
Sntb1Beta-1-syntrophin. (538 aa)
Slc25a4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
Il1aInterleukin-1; Belongs to the IL-1 family. (269 aa)
Casp8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa)
Capn12Calpain-12; Belongs to the peptidase C2 family. (533 aa)
Hsp90ab1Heat shock protein HSP 90-beta. (724 aa)
Ticam1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (733 aa)
ENSMAUP00000020297annotation not available (117 aa)
H1f4Histone H1.4. (219 aa)
H1f2Histone H1.2. (211 aa)
XiapE3 ubiquitin-protein ligase XIAP. (496 aa)
MlklMixed lineage kinase domain-like protein. (439 aa)
Birc2Baculoviral IAP repeat-containing protein 2. (592 aa)
Rnf31E3 ubiquitin-protein ligase RNF31. (1065 aa)
ENSMAUP00000019710annotation not available (70 aa)
Ticam2TIR domain-containing adapter molecule 2. (233 aa)
Tyk2Tyrosine-protein kinase. (1190 aa)
Chmp7Charged multivesicular body protein 7. (450 aa)
LOC101822968Tumor necrosis factor receptor superfamily member 22-like isoform X1. (108 aa)
XkrxXK-related protein. (449 aa)
ENSMAUP00000019352annotation not available (763 aa)
FaddFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
PygbAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
ENSMAUP00000018818annotation not available (199 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
Pla2g4cCytosolic phospholipase A2 gamma isoform X1. (618 aa)
Tlr4Toll-like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
Chmp1bCharged multivesicular body protein 1b. (199 aa)
Macroh2a1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LOC101837947Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)
Rbck1ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X2. (503 aa)
LOC101839247Magnesium-dependent phosphatase 1. (164 aa)
Chmp2aCharged multivesicular body protein 2a. (222 aa)
BaxApoptosis regulator BAX isoform X1. (192 aa)
Macroh2a2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
Stat1Signal transducer and activator of transcription. (749 aa)
ENSMAUP00000015122annotation not available (166 aa)
Glud1Glutamate dehydrogenase 1, mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa)
Sqstm1Sequestosome-1 isoform X1. (442 aa)
LOC101824849Histone H2A; Belongs to the histone H2A family. (121 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
Tnfsf10Tumor necrosis factor ligand superfamily member. (289 aa)
PygmGlycogen phosphorylase, muscle associated. (676 aa)
ENSMAUP00000014485annotation not available (178 aa)
Ifnar1Interferon alpha/beta receptor 1. (543 aa)
Snta1Alpha-1-syntrophin. (491 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
IfngInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (174 aa)
Fth1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (186 aa)
Capn8LOW QUALITY PROTEIN: calpain-8; Belongs to the peptidase C2 family. (729 aa)
Hmgb2High mobility group protein B2. (210 aa)
LOC106022112Histone H2A; Belongs to the histone H2A family. (64 aa)
ENSMAUP00000013239annotation not available (112 aa)
Pelp1Proline-, glutamic acid- and leucine-rich protein 1. (1132 aa)
ENSMAUP00000012618annotation not available (120 aa)
Stat2Signal transducer and activator of transcription 2. (634 aa)
PyglGlycogen phosphorylase L. (728 aa)
Slc25a31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
ENSMAUP00000011880annotation not available (232 aa)
Capn2Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (725 aa)
LOC110339561Signal transducer and activator of transcription 5B-like. (125 aa)
ENSMAUP00000011696annotation not available (450 aa)
Spata2lSpermatogenesis-associated protein 2-like protein. (426 aa)
Pla2g4ePhospholipase A2. (875 aa)
Tmed3Transmembrane emp24 domain-containing protein 3. (220 aa)
Pla2g4aPhospholipase A2. (749 aa)
Faf1FAS-associated factor 1. (593 aa)
ENSMAUP00000011068annotation not available (105 aa)
LOC101834491Cytochrome b-245 heavy chain. (93 aa)
ENSMAUP00000010883annotation not available (214 aa)
2610002M06RikCharged multivesicular body protein 1b-2. (200 aa)
Pla2g4dPhospholipase A2. (862 aa)
Bcl2Apoptosis regulator Bcl-2. (236 aa)
H2awHistone H2A; Belongs to the histone H2A family. (130 aa)
Pla2g4fPhospholipase A2. (849 aa)
Dnm1lDynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (497 aa)
Chmp6Charged multivesicular body protein 6. (200 aa)
Jak3Tyrosine-protein kinase. (1080 aa)
PpidPeptidyl-prolyl cis-trans isomerase D. (370 aa)
Cracr2aEF-hand calcium-binding domain-containing protein 4B isoform X1. (729 aa)
Casp1Caspase-1-like; Belongs to the peptidase C14A family. (313 aa)
ENSMAUP00000008766annotation not available (97 aa)
Vdac3Voltage-dependent anion-selective channel protein 3 isoform X2. (283 aa)
Jak1Tyrosine-protein kinase. (1161 aa)
Il33Interleukin-33. (155 aa)
ENSMAUP00000008492annotation not available (391 aa)
ENSMAUP00000008467annotation not available (125 aa)
H2axHistone H2A; Belongs to the histone H2A family. (143 aa)
ENSMAUP00000007999annotation not available (148 aa)
Usp21Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (567 aa)
Chmp3Charged multivesicular body protein 3. (197 aa)
Capn1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (197 aa)
Pgam5Serine/threonine-protein phosphatase PGAM5, mitochondrial isoform X1. (289 aa)
FasTumor necrosis factor receptor superfamily member 6 isoform X1. (323 aa)
Ripk3Receptor-interacting serine/threonine-protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (483 aa)
Stat3Signal transducer and activator of transcription. (758 aa)
Jak2Tyrosine-protein kinase. (1132 aa)
Parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
FtlFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa)
Rnf103E3 ubiquitin-protein ligase RNF103. (683 aa)
FaslgTumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa)
Smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
SucoSUN domain-containing ossification factor isoform X4. (1254 aa)
Chmp4cCharged multivesicular body protein 4c. (98 aa)
Vdac2Voltage-dependent anion-selective channel protein 2. (295 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
PycardApoptosis-associated speck-like protein containing a CARD. (192 aa)
LOC101842510Signal transducer and activator of transcription 5A. (228 aa)
Rab44Ras-related protein Rab-44. (726 aa)
ENSMAUP00000004541annotation not available (622 aa)
LOC101835406Calpain-3-like. (191 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3. (559 aa)
Ifngr1Interferon gamma receptor 1. (478 aa)
Hmgb4High mobility group protein B4. (175 aa)
H2az2Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC101824534Interferon alpha-12-like. (183 aa)
SharpinSharpin. (154 aa)
Tnfrsf1aTumor necrosis factor receptor superfamily member 1A. (468 aa)
H2ajHistone H2A; Belongs to the histone H2A family. (126 aa)
LOC106021192ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (248 aa)
DhdhTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (297 aa)
Capn11Calpain-11; Belongs to the peptidase C2 family. (613 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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