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| | Cdk1 | Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa) |
| | Rad1 | Cell cycle checkpoint protein RAD1 isoform X1. (280 aa) |
| | Cacna1d | Voltage-dependent L-type calcium channel subunit alpha-1D; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines; B [...] (1378 aa) |
| | ENSMAUP00000022827 | annotation not available (111 aa) |
| | Gadd45g | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | Zfp36l1 | mRNA decay activator protein ZFP36L1. (338 aa) |
| | ENSMAUP00000022689 | annotation not available (268 aa) |
| | Itpr3 | Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa) |
| | Hras | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa) |
| | Tprg1l | Tumor protein p63-regulated gene 1-like protein. (266 aa) |
| | Nras | NRAS proto-oncogene, GTPase. (98 aa) |
| | Pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | E2f3 | Transcription factor E2F3 isoform X1. (460 aa) |
| | Hipk4 | Homeodomain-interacting protein kinase 4. (616 aa) |
| | Cdkn2b | Cyclin-dependent kinase 4 inhibitor B isoform X1. (130 aa) |
| | Rad9b | Cell cycle checkpoint control protein RAD9B. (267 aa) |
| | Capn9 | Calpain-9; Belongs to the peptidase C2 family. (680 aa) |
| | Lin37 | Protein lin-37 homolog isoform X2. (247 aa) |
| | Calm2 | Calmodulin 2. (149 aa) |
| | Cdk2 | Cyclin-dependent kinase 2; Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK [...] (346 aa) |
| | Trpm7 | Transient receptor potential cation channel subfamily M member 7. (1756 aa) |
| | LOC101832695 | H-2 class I histocompatibility antigen, D-37 alpha chain-like isoform X1; Belongs to the MHC class I family. (248 aa) |
| | Traf3ip2-2 | Adapter protein CIKS isoform X2. (264 aa) |
| | Slc25a4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | Rras2 | Ras-related protein R-Ras2. (204 aa) |
| | Il1a | Interleukin-1; Belongs to the IL-1 family. (269 aa) |
| | Capn12 | Calpain-12; Belongs to the peptidase C2 family. (533 aa) |
| | Crybb3 | Beta-crystallin B3; Belongs to the beta/gamma-crystallin family. (199 aa) |
| | LOC101826335 | Saoe class I histocompatibility antigen, A alpha chain-like; Belongs to the MHC class I family. (317 aa) |
| | Tgfb2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | Vdac3 | Voltage-dependent anion-selective channel protein 3 isoform X2. (283 aa) |
| | LOC101831377 | H-2 class I histocompatibility antigen, Q10 alpha chain-like; Belongs to the MHC class I family. (210 aa) |
| | Chek2 | Serine/threonine-protein kinase Chk2. (539 aa) |
| | ENSMAUP00000007717 | annotation not available (351 aa) |
| | Rbbp7 | Histone-binding protein RBBP7. (425 aa) |
| | Capn1 | Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (197 aa) |
| | Sirt1 | NAD-dependent protein deacetylase sirtuin-1. (691 aa) |
| | Bmyc | Protein B-Myc. (173 aa) |
| | Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | ENSMAUP00000006097 | annotation not available (76 aa) |
| | ENSMAUP00000005944 | annotation not available (404 aa) |
| | H2-T24 | H-2 class I histocompatibility antigen, Q7 alpha chain-like; Belongs to the MHC class I family. (345 aa) |
| | Myc | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | Tsc2 | Tuberin. (1760 aa) |
| | Ets1 | Protein C-ets-1 isoform X2. (441 aa) |
| | Pkd1l1 | Polycystic kidney disease protein 1-like 1. (1959 aa) |
| | Rrad | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (307 aa) |
| | Pik3cb | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | Gem | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa) |
| | Vdac2 | Voltage-dependent anion-selective channel protein 2. (295 aa) |
| | Smad2 | Mothers against decapentaplegic homolog. (467 aa) |
| | Hipk3 | Homeodomain-interacting protein kinase 3 isoform X1. (1218 aa) |
| | Pten | Phosphatase and tensin homolog. (403 aa) |
| | Tgfb3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | LOC101835406 | Calpain-3-like. (191 aa) |
| | Mapkapk2 | MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (386 aa) |
| | Rem1 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (297 aa) |
| | Hipk1 | LOW QUALITY PROTEIN: homeodomain-interacting protein kinase 1. (1040 aa) |
| | Gata5 | Transcription factor GATA-5. (406 aa) |
| | Calml3 | Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa) |
| | Ppp3cb | Serine/threonine-protein phosphatase. (483 aa) |
| | E2f2 | Transcription factor E2F2 isoform X1. (449 aa) |
| | Ccnb3 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1356 aa) |
| | Rbl1 | Retinoblastoma-like protein 1 isoform X1. (1063 aa) |
| | Gata6 | Transcription factor GATA-6. (442 aa) |
| | Eras | GTPase ERas. (228 aa) |
| | H2-M2 | Class I histocompatibility antigen, Non-RT1.A alpha-1 chain-like; Belongs to the MHC class I family. (301 aa) |
| | Tgfb1 | Transforming growth factor beta-1. (286 aa) |
| | Rassf5 | Ras association domain-containing protein 5 isoform X2. (265 aa) |
| | Cdkn2a | Cyclin-dependent kinase inhibitor 2A. (157 aa) |
| | Ccne1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa) |
| | Fbxw11 | F-box/WD repeat-containing protein 11 isoform X1. (563 aa) |
| | Mcub | Calcium uniporter regulatory subunit MCUb, mitochondrial isoform X1. (343 aa) |
| | Serpine1 | Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa) |
| | LOC101831400 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa) |
| | Foxm1 | Forkhead box protein M1 isoform X2. (764 aa) |
| | Ppp3r2 | Calcineurin subunit B type 2. (183 aa) |
| | LOC106021192 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (248 aa) |
| | Tgfbr2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | LOC101825196 | mRNA decay activator protein ZFP36L3-like. (502 aa) |
| | Capn11 | Calpain-11; Belongs to the peptidase C2 family. (613 aa) |
| | Ccnb1 | G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily. (447 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | Crygn | Gamma-crystallin N; Belongs to the beta/gamma-crystallin family. (183 aa) |
| | E2f4 | Transcription factor E2F4. (81 aa) |
| | LOC101841110 | LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like. (321 aa) |
| | Cdkn1a | Cyclin-dependent kinase inhibitor 1. (163 aa) |
| | Ppp1cc | Protein phosphatase 1 catalytic subunit gamma. (216 aa) |
| | E2f1 | Transcription factor E2F1. (383 aa) |
| | LOC101827397 | HLA class I histocompatibility antigen, alpha chain F-like; Belongs to the MHC class I family. (202 aa) |
| | Ppp3cc | Serine/threonine-protein phosphatase. (514 aa) |
| | Lin9 | Protein lin-9 homolog. (465 aa) |
| | Tpte | LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like. (670 aa) |
| | Foxo1 | Forkhead box protein O1. (633 aa) |
| | ENSMAUP00000000027 | annotation not available (338 aa) |
| | Ccna2 | Cyclin-A2; Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. Belongs to the cyclin family. Cyclin AB subfamily. (421 aa) |
| | Tesmin | Tesmin. (475 aa) |
| | Nfkb1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa) |
| | Ccnb2 | G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (384 aa) |
| | ENSMAUP00000019419 | annotation not available (406 aa) |
| | ENSMAUP00000019352 | annotation not available (763 aa) |
| | Ccnd1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | Il6 | Interleukin-6. (212 aa) |
| | Hus1 | Checkpoint protein; Belongs to the HUS1 family. (281 aa) |
| | Kras | GTPase KRas isoform X3. (189 aa) |
| | Rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) |
| | Mapk13 | Mitogen-activated protein kinase. (366 aa) |
| | Mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa) |
| | Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa) |
| | Pik3r2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa) |
| | LOC101832429 | H-2 class I histocompatibility antigen, Q9 alpha chain-like; Belongs to the MHC class I family. (205 aa) |
| | Ccnd2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (288 aa) |
| | Trpv4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa) |
| | Mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (203 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Ppp1ca | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | Btrc | F-box/WD repeat-containing protein 1A isoform X2. (605 aa) |
| | Mapk14 | Mitogen-activated protein kinase. (360 aa) |
| | ENSMAUP00000016715 | annotation not available (418 aa) |
| | Mtor | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | Raf1 | RAF proto-oncogene serine/threonine-protein kinase. (648 aa) |
| | Rela | Transcription factor p65 isoform X1. (260 aa) |
| | Ppp1cb | Protein phosphatase 1 catalytic subunit beta. (298 aa) |
| | Gadd45b | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | Calml4 | Calmodulin-like protein 4 isoform X2. (141 aa) |
| | Rbl2 | Retinoblastoma-like protein 2 isoform X2. (1134 aa) |
| | Ppp3r1 | Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (157 aa) |
| | Rheb | GTP-binding protein Rheb. (109 aa) |
| | ENSMAUP00000014844 | annotation not available (634 aa) |
| | Sqstm1 | Sequestosome-1 isoform X1. (442 aa) |
| | Cdk3 | Cyclin-dependent kinase 3 isoform X2; Belongs to the protein kinase superfamily. (297 aa) |
| | Azgp1 | Zinc-alpha-2-glycoprotein; Belongs to the MHC class I family. (312 aa) |
| | Tprg | Tumor protein p63-regulated gene 1 protein. (174 aa) |
| | Gata4 | Transcription factor GATA-4 isoform X2. (443 aa) |
| | Csde1 | Cold shock domain-containing protein E1 isoform X3. (798 aa) |
| | Rbbp4 | RB binding protein 4, chromatin remodeling factor. (391 aa) |
| | Foxo3 | Forkhead box protein O3. (672 aa) |
| | Nfatc1 | Nuclear factor of activated T-cells, cytoplasmic 1. (898 aa) |
| | Capn8 | LOW QUALITY PROTEIN: calpain-8; Belongs to the peptidase C2 family. (729 aa) |
| | Atr | Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2148 aa) |
| | Traf3ip2 | Adapter protein CIKS isoform X4. (109 aa) |
| | Tgfbr1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | Rhebl1 | GTPase RhebL1 isoform X2. (182 aa) |
| | E2f5 | Transcription factor E2F5 isoform X1. (334 aa) |
| | Ccna1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | Eif4ebp1 | Eukaryotic translation initiation factor 4E-binding protein 1. (117 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Gadd45a | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | Itpr2 | Inositol 1,4,5-trisphosphate receptor type 2. (2584 aa) |
| | Igfbp3 | Insulin-like growth factor-binding protein 3. (292 aa) |
| | Chek1 | Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa) |
| | Nfatc4 | Nuclear factor of activated T-cells, cytoplasmic 4. (728 aa) |
| | ENSMAUP00000012323 | annotation not available (353 aa) |
| | Slc25a31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa) |
| | ENSMAUP00000011880 | annotation not available (232 aa) |
| | Lin54 | Protein lin-54 homolog isoform X1. (749 aa) |
| | Ppp3ca | Serine/threonine-protein phosphatase. (521 aa) |
| | Capn2 | Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (725 aa) |
| | Mapk3 | Mitogen-activated protein kinase. (380 aa) |
| | Atm | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3014 aa) |
| | Nfatc2 | Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (929 aa) |
| | Map2k2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | Ccne2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | Calm3 | Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa) |
| | Lin52 | Protein lin-52 homolog. (116 aa) |
| | Map2k1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | Hipk2 | Homeodomain-interacting protein kinase 2; Serine/threonine-protein kinase involved in transcription regulation, p53/TP53-mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1/Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53/TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53/TP53 both at the transcription level and at the protein level (by phosphorylation and indirect [...] (1180 aa) |
| | Mras | Ras-related protein M-Ras. (208 aa) |
| | Rad50 | DNA repair protein RAD50. (1312 aa) |
| | Cdk4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | Ccnd3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) |
| | Ppid | Peptidyl-prolyl cis-trans isomerase D. (370 aa) |
| | LOC101831914 | H-2 class I histocompatibility antigen, Q10 alpha chain-like; Belongs to the MHC class I family. (351 aa) |
| | Kiaa1671 | Uncharacterized protein KIAA1671 homolog isoform X3. (387 aa) |
| | Mapk11 | Mitogen-activated protein kinase. (355 aa) |
| | Smad3 | Mothers against decapentaplegic homolog. (425 aa) |
| | Tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (395 aa) |
| | Calm1 | Calmodulin 1. (149 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (270 aa) |
| | Rras | Ras-related protein R-Ras. (218 aa) |
| | LOC106021121 | Uncharacterized protein LOC106021121. (209 aa) |
| | Mapk12 | Mitogen-activated protein kinase. (367 aa) |
| | LOC101839104 | Insulin-like growth factor-binding protein 3. (177 aa) |
| | Efcab3 | EF-hand calcium-binding domain-containing protein 3. (430 aa) |
| | Nbn | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (556 aa) |
| | Tsc1 | Hamartin isoform X1. (1160 aa) |
| | Mcu | Calcium uniporter protein, mitochondrial isoform X1. (350 aa) |
| | Pik3r2-2 | Phosphoinositide-3-kinase regulatory subunit 2. (71 aa) |
| | Cdk6 | Cyclin-dependent kinase 6. (203 aa) |
| | Map2k6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (334 aa) |
| | Rb1 | Retinoblastoma-associated protein. (906 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Map2k3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
