STRINGSTRING
Htr2c Htr2c Prkg1 Prkg1 Src Src Gnaq Gnaq Csnk1d Csnk1d Tuba4a Tuba4a Pdgfb Pdgfb Drd2 Drd2 Adcy6 Adcy6 Map2k1 Map2k1 Drd1 Drd1 Adcy5 Adcy5 Gucy1a2 Gucy1a2 Map2k2 Map2k2 Prkcg Prkcg Tubb3 Tubb3 ENSMAUP00000002428 ENSMAUP00000002428 ENSMAUP00000002714 ENSMAUP00000002714 Prkacb Prkacb ENSMAUP00000002946 ENSMAUP00000002946 Grm1 Grm1 Prkg2 Prkg2 Gucy1b1 Gucy1b1 Sos1 Sos1 Tubb6 Tubb6 Gjd2 Gjd2 Egfr Egfr Tubb1 Tubb1 ENSMAUP00000000935 ENSMAUP00000000935 Gnai1 Gnai1 LOC101831620 LOC101831620 Adcy4 Adcy4 Grm5 Grm5 Eras Eras Gna11 Gna11 Ercc3 Ercc3 Tubb4b Tubb4b Prkaca Prkaca Rem1 Rem1 Adcy7 Adcy7 LOC110341725 LOC110341725 Pdgfa Pdgfa Gucy1b2 Gucy1b2 ENSMAUP00000023426 ENSMAUP00000023426 Cdk1 Cdk1 Map3k2 Map3k2 Tubb Tubb Itpr3 Itpr3 Hras Hras Nras Nras Adcy3 Adcy3 Ptrhd1 Ptrhd1 Pdgfra Pdgfra Gucy1a3 Gucy1a3 Gnas Gnas Adcy1 Adcy1 Htr2a Htr2a Pdgfrb Pdgfrb Mapk3 Mapk3 Gnai2 Gnai2 Plcb4 Plcb4 Itpr2 Itpr2 Pdgfd Pdgfd Mapk7 Mapk7 Prkcb Prkcb Sos2 Sos2 Lpar1 Lpar1 Tjp1 Tjp1 LOC101834284 LOC101834284 Csde1 Csde1 Adcy2 Adcy2 Adcy8 Adcy8 Htr2b Htr2b Pdgfc Pdgfc Plcb1 Plcb1 Map2k5 Map2k5 Raf1 Raf1 Egf Egf Adcy9 Adcy9 Tuba8 Tuba8 Gja6 Gja6 Grb2 Grb2 Itpr1 Itpr1 Mapk1 Mapk1 Kras Kras Tubb4a Tubb4a LOC106020738 LOC106020738 Tubb2a Tubb2a Plcb2 Plcb2 Gja1 Gja1 Gem Gem Rrad Rrad Gnai3 Gnai3 Tubal3 Tubal3 LOC106021271 LOC106021271 Prkca Prkca ENSMAUP00000007160 ENSMAUP00000007160
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Htr2c5-hydroxytryptamine receptor 2C. (393 aa)
Prkg1cGMP-dependent protein kinase 1. (437 aa)
SrcTyrosine-protein kinase. (536 aa)
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
Csnk1dCasein kinase I isoform X1; Belongs to the protein kinase superfamily. (415 aa)
Tuba4aTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
PdgfbPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (221 aa)
Drd2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (444 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
Drd1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
Adcy5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
Gucy1a2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (731 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
Tubb3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
ENSMAUP00000002428annotation not available (67 aa)
ENSMAUP00000002714annotation not available (58 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
ENSMAUP00000002946annotation not available (431 aa)
Grm1Metabotropic glutamate receptor 1. (829 aa)
Prkg2cGMP-dependent protein kinase. (713 aa)
Gucy1b1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
Sos1Son of sevenless homolog 1. (1319 aa)
Tubb6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
Gjd2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (321 aa)
EgfrReceptor protein-tyrosine kinase. (1207 aa)
Tubb1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (446 aa)
ENSMAUP00000000935annotation not available (393 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
LOC101831620Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
Grm5Metabotropic glutamate receptor 5 isoform X1. (1203 aa)
ErasGTPase ERas. (228 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
Ercc3TFIIH basal transcription factor complex helicase XPB subunit. (783 aa)
Tubb4bTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Rem1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (297 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
PdgfaPlatelet-derived growth factor subunit A isoform X1; Belongs to the PDGF/VEGF growth factor family. (211 aa)
Gucy1b2Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (757 aa)
ENSMAUP00000023426annotation not available (405 aa)
Cdk1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
Map3k2Mitogen-activated protein kinase kinase kinase 2 isoform X1. (619 aa)
TubbTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
HrasGTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
NrasNRAS proto-oncogene, GTPase. (98 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
Ptrhd1LOW QUALITY PROTEIN: putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
PdgfraPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
Gucy1a3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (128 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1118 aa)
Htr2a5-hydroxytryptamine receptor 2A. (471 aa)
PdgfrbPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (703 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (2584 aa)
PdgfdPlatelet-derived growth factor D. (313 aa)
Mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa)
PrkcbProtein kinase C beta. (554 aa)
Sos2Son of sevenless homolog 2 isoform X1. (1308 aa)
Lpar1Lysophosphatidic acid receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Tjp1Tight junction protein ZO-1 isoform X8; Belongs to the MAGUK family. (1685 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
Csde1Cold shock domain-containing protein E1 isoform X3. (798 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
Htr2b5-hydroxytryptamine receptor 2B. (480 aa)
PdgfcPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Map2k5Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily. (448 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
EgfPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (254 aa)
Adcy9Adenylate cyclase type 9 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
Tuba8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (397 aa)
Gja6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (284 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
KrasGTPase KRas isoform X3. (189 aa)
Tubb4aTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
LOC106020738Tubulin beta-4B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family. (100 aa)
Tubb2aTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
Gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
GemGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
RradGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (307 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Tubal3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
LOC106021271cGMP-dependent protein kinase 1-like isoform X2. (92 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ENSMAUP00000007160annotation not available (330 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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