57 items (Mesocricetus auratus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Mapk10	Mitogen-activated protein kinase 10. (252 aa)
	Azi2	5-azacytidine-induced protein 2 isoform X1. (405 aa)
	Ddx58	Putative ATP-dependent RNA helicase DDX58. (908 aa)
	Traf3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	Trim65	Tripartite motif-containing protein 65. (519 aa)
	Dhx58	Probable ATP-dependent RNA helicase DHX58. (678 aa)
	Irf7	Interferon regulatory factor 7 isoform X1. (394 aa)
	Coil	Coilin. (544 aa)
	Tmem173	Stimulator of interferon genes protein. (379 aa)
	Tbkbp1	TANK-binding kinase 1-binding protein 1 isoform X3. (613 aa)
	Casp8	Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa)
	Nfkb1	Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa)
	Trim47	Tripartite motif-containing protein 47. (641 aa)
	Fadd	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
	Atg12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (141 aa)
	Mapk13	Mitogen-activated protein kinase. (366 aa)
	Mapk9	Mitogen-activated protein kinase. (423 aa)
	Chuk	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
	Map3k7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (497 aa)
	Atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	Mapk14	Mitogen-activated protein kinase. (360 aa)
	Rela	Transcription factor p65 isoform X1. (260 aa)
	Otud5	OTU domain-containing protein 5 isoform X1. (567 aa)
	Ikbkb	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa)
	Nfkbib	NF-kappa-B inhibitor beta. (358 aa)
	Mavs	Mitochondrial antiviral-signaling protein isoform X1. (498 aa)
	Tnf	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	Cxcl10	C-X-C motif chemokine. (98 aa)
	Tank	TRAF family member-associated NF-kappa-B activator isoform X2. (443 aa)
	Sike1	Suppressor of IKBKE 1. (207 aa)
	Fgfr1op2	FGFR1 oncogene partner 2 isoform X1. (253 aa)
	Tkfc	triokinase/FMN cyclase. (578 aa)
	Rnf125	E3 ubiquitin-protein ligase RNF125. (126 aa)
	Isg15	Ubiquitin-like protein ISG15. (160 aa)
	Ikbkg	NF-kappa-B essential modulator isoform X1. (412 aa)
	Ikbke	Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (715 aa)
	ENSMAUP00000006088	annotation not available (179 aa)
	Trim25	E3 ubiquitin/ISG15 ligase TRIM25. (602 aa)
	Map3k1	Mitogen-activated protein kinase kinase kinase 1. (1475 aa)
	Il12a	Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (206 aa)
	Mapk8	Mitogen-activated protein kinase. (427 aa)
	Nfkbia	NF-kappa-B inhibitor alpha. (314 aa)
	Traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
	LOC101824534	Interferon alpha-12-like. (183 aa)
	Ifnk	Interferon kappa. (197 aa)
	Cyld	Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (956 aa)
	Traf2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
	Tbk1	Serine/threonine-protein kinase TBK1. (729 aa)
	Ripk1	Receptor-interacting serine/threonine-protein kinase 1. (658 aa)
	Pin1	Peptidyl-prolyl cis-trans isomerase. (165 aa)
	D1Pas1	Putative ATP-dependent RNA helicase Pl10 isoform X2; Belongs to the DEAD box helicase family. (665 aa)
	Tradd	Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2. (310 aa)
	Mapk11	Mitogen-activated protein kinase. (355 aa)
	Rnf135	E3 ubiquitin-protein ligase RNF135 isoform X2. (412 aa)
	Irf3	Interferon regulatory factor 3 isoform X1. (420 aa)
	Mapk12	Mitogen-activated protein kinase. (367 aa)
	Ddx3x	ATP-dependent RNA helicase DDX3X; Belongs to the DEAD box helicase family. (662 aa)

Your Current Organism:

Mesocricetus auratus

NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg12	Atg5	ENSMAUP00000019282	ENSMAUP00000017377	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
Atg12	Casp8	ENSMAUP00000019282	ENSMAUP00000020452	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	0.564
Atg12	Ddx58	ENSMAUP00000019282	ENSMAUP00000025205	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Putative ATP-dependent RNA helicase DDX58.	0.946
Atg12	Dhx58	ENSMAUP00000019282	ENSMAUP00000022537	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Probable ATP-dependent RNA helicase DHX58.	0.865
Atg12	Fadd	ENSMAUP00000019282	ENSMAUP00000019349	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.694
Atg12	Mavs	ENSMAUP00000019282	ENSMAUP00000015057	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Mitochondrial antiviral-signaling protein isoform X1.	0.976
Atg5	Atg12	ENSMAUP00000017377	ENSMAUP00000019282	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
Atg5	Casp8	ENSMAUP00000017377	ENSMAUP00000020452	Autophagy protein 5; Involved in autophagic vesicle formation.	Caspase-8 isoform X1; Belongs to the peptidase C14A family.	0.761
Atg5	Ddx58	ENSMAUP00000017377	ENSMAUP00000025205	Autophagy protein 5; Involved in autophagic vesicle formation.	Putative ATP-dependent RNA helicase DDX58.	0.946
Atg5	Dhx58	ENSMAUP00000017377	ENSMAUP00000022537	Autophagy protein 5; Involved in autophagic vesicle formation.	Probable ATP-dependent RNA helicase DHX58.	0.858
Atg5	Fadd	ENSMAUP00000017377	ENSMAUP00000019349	Autophagy protein 5; Involved in autophagic vesicle formation.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.783
Atg5	Mavs	ENSMAUP00000017377	ENSMAUP00000015057	Autophagy protein 5; Involved in autophagic vesicle formation.	Mitochondrial antiviral-signaling protein isoform X1.	0.973
Atg5	Ripk1	ENSMAUP00000017377	ENSMAUP00000000704	Autophagy protein 5; Involved in autophagic vesicle formation.	Receptor-interacting serine/threonine-protein kinase 1.	0.589
Azi2	Chuk	ENSMAUP00000025277	ENSMAUP00000018727	5-azacytidine-induced protein 2 isoform X1.	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	0.664
Azi2	Ikbkb	ENSMAUP00000025277	ENSMAUP00000015615	5-azacytidine-induced protein 2 isoform X1.	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	0.664
Azi2	Ikbke	ENSMAUP00000025277	ENSMAUP00000006400	5-azacytidine-induced protein 2 isoform X1.	Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1.	0.941
Azi2	Ikbkg	ENSMAUP00000025277	ENSMAUP00000006591	5-azacytidine-induced protein 2 isoform X1.	NF-kappa-B essential modulator isoform X1.	0.884
Azi2	Tank	ENSMAUP00000025277	ENSMAUP00000012333	5-azacytidine-induced protein 2 isoform X1.	TRAF family member-associated NF-kappa-B activator isoform X2.	0.925
Azi2	Tbk1	ENSMAUP00000025277	ENSMAUP00000000714	5-azacytidine-induced protein 2 isoform X1.	Serine/threonine-protein kinase TBK1.	0.996
Azi2	Tnf	ENSMAUP00000025277	ENSMAUP00000014584	5-azacytidine-induced protein 2 isoform X1.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.986

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