STRINGSTRING
ENSMAUP00000006097 ENSMAUP00000006097 Ccl17 Ccl17 Ppp3cc Ppp3cc Egr3 Egr3 ENSMAUP00000001156 ENSMAUP00000001156 Cyld Cyld Pik3cd Pik3cd Clec4g Clec4g Ppp3r2 Ppp3r2 LOC101831400 LOC101831400 Eras Eras Malt1 Malt1 Ppp3cb Ppp3cb Calml3 Calml3 Clec4d Clec4d Rem1 Rem1 Mapkapk2 Mapkapk2 Nfkbia Nfkbia Pycard Pycard Mapk8 Mapk8 Il12a Il12a Map3k14 Map3k14 Gem Gem Pik3cb Pik3cb Jun Jun Rrad Rrad Ksr1 Ksr1 Plcg2 Plcg2 Ceacam9 Ceacam9 Pik3r1 Pik3r1 Ikbke Ikbke Ikbkg Ikbkg Plk5 Plk5 Il10 Il10 Irf1 Irf1 Clec1a Clec1a Clec7a Clec7a Src Src LOC110340161 LOC110340161 Casp1 Casp1 ENSMAUP00000009019 ENSMAUP00000009019 Pak1 Pak1 Mras Mras Ceacam16 Ceacam16 Il23a Il23a Bcl10 Bcl10 Rhoc Rhoc Calm3 Calm3 Tmem52b Tmem52b Nfatc2 Nfatc2 Cd209e Cd209e Mapk3 Mapk3 Ppp3ca Ppp3ca Nfatc4 Nfatc4 Psg29 Psg29 Stat2 Stat2 Itpr2 Itpr2 Akt1 Akt1 Arhgef12 Arhgef12 Nfatc1 Nfatc1 Ptpn11 Ptpn11 Csde1 Csde1 ENSMAUP00000014320 ENSMAUP00000014320 Tnf Tnf ENSMAUP00000014844 ENSMAUP00000014844 Ppp3r1 Ppp3r1 Calml4 Calml4 Ikbkb Ikbkb Rhoa Rhoa Fcer1g Fcer1g Stat1 Stat1 Rela Rela Raf1 Raf1 LOC101830849 LOC101830849 Cd209b Cd209b Mapk14 Mapk14 Akt3 Akt3 4930544G11Rik 4930544G11Rik Nfkb2 Nfkb2 Cd209a Cd209a Clec4n Clec4n Pik3r2 Pik3r2 Itpr1 Itpr1 Mapk10 Mapk10 Relb Relb Mapk1 Mapk1 Il2 Il2 Mapk13 Mapk13 Mapk9 Mapk9 Chuk Chuk Kras Kras Clec9a Clec9a Clec1b Clec1b Ccl22 Ccl22 Il1b Il1b Il6 Il6 Nfkb1 Nfkb1 Plk3 Plk3 Lsp1 Lsp1 Casp8 Casp8 Rras2 Rras2 Clec4e Clec4e LOC101840132 LOC101840132 Ptgs2 Ptgs2 Bcl3 Bcl3 Syk Syk Calm2 Calm2 Pik3ca Pik3ca Nras Nras Hras Hras Itpr3 Itpr3 Nlrp3 Nlrp3 Irf9 Irf9 Card9 Card9 Akt2 Akt2 Egr2 Egr2 Pik3r2-2 Pik3r2-2 Prkcd Prkcd Efcab3 Efcab3 Mapk12 Mapk12 LOC106021121 LOC106021121 Rras Rras MDM2 MDM2 Calm1 Calm1 Mapk11 Mapk11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAUP00000006097annotation not available (76 aa)
Ccl17C-C motif chemokine. (103 aa)
Ppp3ccSerine/threonine-protein phosphatase. (514 aa)
Egr3Early growth response protein 3 isoform X2. (387 aa)
ENSMAUP00000001156annotation not available (229 aa)
CyldUbiquitin carboxyl-terminal hydrolase CYLD isoform X1; Belongs to the peptidase C19 family. (956 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
Clec4gC-type lectin domain family 4 member G. (293 aa)
Ppp3r2Calcineurin subunit B type 2. (183 aa)
LOC101831400Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa)
ErasGTPase ERas. (228 aa)
Malt1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X2. (823 aa)
Ppp3cbSerine/threonine-protein phosphatase. (483 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Clec4dC-type lectin domain family 4 member D isoform X1. (221 aa)
Rem1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (297 aa)
Mapkapk2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (386 aa)
NfkbiaNF-kappa-B inhibitor alpha. (314 aa)
PycardApoptosis-associated speck-like protein containing a CARD. (192 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
Il12aInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (206 aa)
Map3k14Mitogen-activated protein kinase kinase kinase 14. (941 aa)
GemGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
JunTranscription factor AP-1; Belongs to the bZIP family. (338 aa)
RradGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (307 aa)
Ksr1Kinase suppressor of Ras 1 isoform X4. (912 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
Ceacam9Carcinoembryonic antigen-related cell adhesion molecule 3-like. (234 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
IkbkeInhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (715 aa)
IkbkgNF-kappa-B essential modulator isoform X1. (412 aa)
Plk5Inactive serine/threonine-protein kinase PLK5. (579 aa)
Il10Interleukin-10 isoform X1. (178 aa)
Irf1Interferon regulatory factor. (132 aa)
Clec1aC-type lectin domain family 1 member A isoform X1. (272 aa)
Clec7aC-type lectin domain family 7 member A isoform X2. (243 aa)
SrcTyrosine-protein kinase. (536 aa)
LOC110340161C-type lectin domain family 4 member A-like. (151 aa)
Casp1Caspase-1-like; Belongs to the peptidase C14A family. (313 aa)
ENSMAUP00000009019annotation not available (475 aa)
Pak1P21 (RAC1) activated kinase 1. (490 aa)
MrasRas-related protein M-Ras. (208 aa)
Ceacam16Carcinoembryonic antigen-related cell adhesion molecule 16. (431 aa)
Il23aInterleukin-23 subunit alpha. (196 aa)
Bcl10B-cell lymphoma/leukemia 10. (232 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
Tmem52bTransmembrane protein 52B. (186 aa)
Nfatc2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (929 aa)
Cd209eCD209 antigen-like protein E. (214 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Ppp3caSerine/threonine-protein phosphatase. (521 aa)
Nfatc4Nuclear factor of activated T-cells, cytoplasmic 4. (728 aa)
Psg29Pregnancy-specific glycoprotein 29. (465 aa)
Stat2Signal transducer and activator of transcription 2. (634 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (2584 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Arhgef12Rho guanine nucleotide exchange factor 12 isoform X1. (1544 aa)
Nfatc1Nuclear factor of activated T-cells, cytoplasmic 1. (898 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
Csde1Cold shock domain-containing protein E1 isoform X3. (798 aa)
ENSMAUP00000014320annotation not available (157 aa)
TnfTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ENSMAUP00000014844annotation not available (634 aa)
Ppp3r1Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (157 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa)
RhoaTransforming protein RhoA-like isoform X2. (141 aa)
Fcer1gHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
Stat1Signal transducer and activator of transcription. (749 aa)
RelaTranscription factor p65 isoform X1. (260 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
LOC101830849B-cell lymphoma 3 protein homolog. (114 aa)
Cd209bCD209 antigen-like protein B isoform X2. (326 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
4930544G11RikTransforming protein RhoA-like isoform X1. (193 aa)
Nfkb2Nuclear factor NF-kappa-B p100 subunit isoform X2. (898 aa)
Cd209aCD209 antigen-like protein A. (211 aa)
Clec4nC-type lectin domain family 6 member A. (179 aa)
Pik3r2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
RelbTranscription factor RelB. (191 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
Il2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa)
Mapk13Mitogen-activated protein kinase. (366 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
ChukInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
KrasGTPase KRas isoform X3. (189 aa)
Clec9aC-type lectin domain family 9 member A. (240 aa)
Clec1bC-type lectin domain family 1 member B isoform X1. (229 aa)
Ccl22C-C motif chemokine. (93 aa)
Il1bMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
Il6Interleukin-6. (212 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa)
Plk3Serine/threonine-protein kinase PLK. (648 aa)
Lsp1Lymphocyte-specific protein 1 isoform X1. (330 aa)
Casp8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa)
Rras2Ras-related protein R-Ras2. (204 aa)
Clec4eC-type lectin domain family 4 member E. (215 aa)
LOC101840132Carcinoembryonic antigen-related cell adhesion molecule 5-like. (141 aa)
Ptgs2Prostaglandin G/H synthase 2. (604 aa)
Bcl3B-cell lymphoma 3 protein. (292 aa)
SykTyrosine-protein kinase. (629 aa)
Calm2Calmodulin 2. (149 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
NrasNRAS proto-oncogene, GTPase. (98 aa)
HrasGTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
Nlrp3NACHT, LRR and PYD domains-containing protein 3 isoform X1. (1036 aa)
Irf9Interferon regulatory factor 9 isoform X1. (390 aa)
Card9Caspase recruitment domain-containing protein 9 isoform X2. (537 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Egr2E3 SUMO-protein ligase EGR2 isoform X1. (468 aa)
Pik3r2-2Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
PrkcdProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
Efcab3EF-hand calcium-binding domain-containing protein 3. (430 aa)
Mapk12Mitogen-activated protein kinase. (367 aa)
LOC106021121Uncharacterized protein LOC106021121. (209 aa)
RrasRas-related protein R-Ras. (218 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (270 aa)
Calm1Calmodulin 1. (149 aa)
Mapk11Mitogen-activated protein kinase. (355 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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