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| | Fos | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa) |
| | Rxrg | Retinoic acid receptor RXR-gamma isoform X1. (463 aa) |
| | Hif1a | Hypoxia-inducible factor 1-alpha isoform X1. (246 aa) |
| | Cd247 | LOW QUALITY PROTEIN: T-cell surface glycoprotein CD3 zeta chain. (163 aa) |
| | Il2ra | Interleukin-2 receptor subunit alpha. (267 aa) |
| | H2-Ab1 | Rano class II histocompatibility antigen, A beta chain-like. (263 aa) |
| | Il1rap | Interleukin-1 receptor accessory protein. (570 aa) |
| | Mapk12 | Mitogen-activated protein kinase. (367 aa) |
| | ENSMAUP00000025679 | annotation not available (108 aa) |
| | Smad3 | Mothers against decapentaplegic homolog. (425 aa) |
| | Mapk11 | Mitogen-activated protein kinase. (355 aa) |
| | Il1r1 | Interleukin-1 receptor type 1. (293 aa) |
| | Il21 | Interleukin; Belongs to the IL-15/IL-21 family. (147 aa) |
| | Stat6 | Signal transducer and activator of transcription. (746 aa) |
| | Chuk | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa) |
| | Mapk9 | Mitogen-activated protein kinase. (423 aa) |
| | Mapk13 | Mitogen-activated protein kinase. (366 aa) |
| | Il2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (155 aa) |
| | Mapk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa) |
| | Mapk10 | Mitogen-activated protein kinase 10. (252 aa) |
| | Rxra | Retinoic acid receptor RXR-alpha. (457 aa) |
| | Runx1-2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (62 aa) |
| | Il6st | Interleukin-6 receptor subunit beta. (770 aa) |
| | Gata3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (443 aa) |
| | Foxp3 | Forkhead box protein P3 isoform X3. (427 aa) |
| | ENSMAUP00000017208 | annotation not available (174 aa) |
| | Mapk14 | Mitogen-activated protein kinase. (360 aa) |
| | Foxs1 | Forkhead box protein S1. (329 aa) |
| | LOC101824859 | Interleukin-6 receptor subunit beta-like. (142 aa) |
| | Irf4 | Interferon regulatory factor 4 isoform X3. (450 aa) |
| | Mtor | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | Il12rb1 | Interleukin-12 receptor subunit beta-1 isoform X5. (741 aa) |
| | Rela | Transcription factor p65 isoform X1. (260 aa) |
| | Rorc | Nuclear receptor ROR-gamma isoform X2. (520 aa) |
| | Stat1 | Signal transducer and activator of transcription. (749 aa) |
| | Ikbkb | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa) |
| | Nfkbib | NF-kappa-B inhibitor beta. (358 aa) |
| | Ppp3r1 | Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (157 aa) |
| | H2-Ea-ps | H-2 class II histocompatibility antigen, E-U alpha chain; Belongs to the MHC class II family. (256 aa) |
| | ENSMAUP00000014844 | annotation not available (634 aa) |
| | Rara | Retinoic acid receptor alpha isoform X1. (462 aa) |
| | Il17f | interleukin-17F. (162 aa) |
| | Il23r | Interleukin-23 receptor. (646 aa) |
| | Il17a | interleukin-17A. (158 aa) |
| | Il21r | Interleukin-21 receptor. (537 aa) |
| | H2-Oa | HLA class II histocompatibility antigen, DO alpha chain isoform X1; Belongs to the MHC class II family. (250 aa) |
| | Runx1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (68 aa) |
| | Lck | Tyrosine-protein kinase. (316 aa) |
| | Ifng | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (174 aa) |
| | Nfatc1 | Nuclear factor of activated T-cells, cytoplasmic 1. (898 aa) |
| | Tgfbr1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | Ppp3ca | Serine/threonine-protein phosphatase. (521 aa) |
| | LOC110339561 | Signal transducer and activator of transcription 5B-like. (125 aa) |
| | Mapk3 | Mitogen-activated protein kinase. (380 aa) |
| | Nfkbie | NF-kappa-B inhibitor epsilon. (362 aa) |
| | Il22 | Interleukin-22. (180 aa) |
| | Lat | Linker for activation of T-cells family member 1 isoform X1. (241 aa) |
| | Il4r | Interleukin-4 receptor subunit alpha. (42 aa) |
| | Nfatc2 | Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (929 aa) |
| | Il2rg | Cytokine receptor common subunit gamma isoform X1. (363 aa) |
| | Il23a | Interleukin-23 subunit alpha. (196 aa) |
| | Hck | Tyrosine-protein kinase. (519 aa) |
| | Il6r | Interleukin-6 receptor subunit alpha. (460 aa) |
| | Jak3 | Tyrosine-protein kinase. (1080 aa) |
| | Dusp15 | Dual specificity protein phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (192 aa) |
| | Jak1 | Tyrosine-protein kinase. (1161 aa) |
| | ENSMAUP00000008492 | annotation not available (391 aa) |
| | ENSMAUP00000008458 | annotation not available (123 aa) |
| | Cd3e | T-cell surface glycoprotein CD3 epsilon chain. (188 aa) |
| | Smad4 | Mothers against decapentaplegic homolog. (552 aa) |
| | Il4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (147 aa) |
| | Rxrb | Retinoic acid receptor RXR-beta. (414 aa) |
| | ENSMAUP00000007177 | annotation not available (91 aa) |
| | Stat3 | Signal transducer and activator of transcription. (758 aa) |
| | Jak2 | Tyrosine-protein kinase. (1132 aa) |
| | Cd4 | T-cell surface glycoprotein CD4. (397 aa) |
| | Ikbkg | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | Cd3g | T-cell surface glycoprotein CD3 gamma chain. (182 aa) |
| | Cd3d | T-cell surface glycoprotein CD3 delta chain precursor. (171 aa) |
| | H2-Ob | HLA class II histocompatibility antigen, DO beta chain. (274 aa) |
| | Jun | Transcription factor AP-1; Belongs to the bZIP family. (338 aa) |
| | Smad2 | Mothers against decapentaplegic homolog. (467 aa) |
| | Mapk8 | Mitogen-activated protein kinase. (427 aa) |
| | LOC101842510 | Signal transducer and activator of transcription 5A. (228 aa) |
| | Nfkbia | NF-kappa-B inhibitor alpha. (314 aa) |
| | ENSMAUP00000004541 | annotation not available (622 aa) |
| | Ifngr1 | Interferon gamma receptor 1. (478 aa) |
| | Ppp3cb | Serine/threonine-protein phosphatase. (483 aa) |
| | Il27ra | Interleukin-27 receptor subunit alpha isoform X1. (631 aa) |
| | Tgfb1 | Transforming growth factor beta-1. (286 aa) |
| | H2-Aa | H-2 class II histocompatibility antigen, A-U alpha chain. (173 aa) |
| | Ppp3r2 | Calcineurin subunit B type 2. (183 aa) |
| | Tgfbr2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | LOC101835654 | Signal transducer and activator of transcription. (228 aa) |
| | Plcg1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1293 aa) |
| | H2-DMa | Class II histocompatibility antigen, M alpha chain; Belongs to the MHC class II family. (261 aa) |
| | Ppp3cc | Serine/threonine-protein phosphatase. (514 aa) |
| | Il1b | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) |
| | Tbx21 | T-box transcription factor TBX21. (529 aa) |
| | Il6 | Interleukin-6. (212 aa) |
| | Tyk2 | Tyrosine-protein kinase. (1190 aa) |
| | Nfkb1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa) |
| | Ahr | Aryl hydrocarbon receptor. (731 aa) |
| | LOC101843733 | H-2 class II histocompatibility antigen, E-D beta chain-like. (181 aa) |
| | Hsp90ab1 | Heat shock protein HSP 90-beta. (724 aa) |
| | ENSMAUP00000020463 | annotation not available (168 aa) |
| | Il2rb | Interleukin-2 receptor subunit beta. (415 aa) |
| | Rora | Nuclear receptor ROR-alpha isoform X1. (523 aa) |
| | Zap70 | Tyrosine-protein kinase. (617 aa) |
| | Prkcq | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa) |
