STRINGSTRING
ENSMAUP00000017507 ENSMAUP00000017507 Vcam1 Vcam1 Rassf5 Rassf5 LOC101825458 LOC101825458 Cldn2 Cldn2 LOC101831400 LOC101831400 ENSMAUP00000002714 ENSMAUP00000002714 Actg1 Actg1 Pik3cd Pik3cd Plcg1 Plcg1 Prkcg Prkcg Actn4 Actn4 Ctnnb1 Ctnnb1 Ctnna2 Ctnna2 Itgb1 Itgb1 Gnai1 Gnai1 Jam3 Jam3 Arhgap35 Arhgap35 Actl9 Actl9 Ptk2 Ptk2 Cdc42 Cdc42 Actl7a Actl7a Cd99l2 Cd99l2 Vcl Vcl Mmp9 Mmp9 Actl7b Actl7b Icam1 Icam1 Esam Esam Msn Msn Pik3cb Pik3cb Ezr Ezr Plcg2 Plcg2 Arhgap5 Arhgap5 Gnai3 Gnai3 Pik3r1 Pik3r1 Cldn4 Cldn4 Vav3 Vav3 Cldn3 Cldn3 Actb Actb Prkca Prkca Cldn23 Cldn23 Cldn10 Cldn10 Cldn20 Cldn20 Cldn9 Cldn9 Cldn22 Cldn22 Cldn16 Cldn16 Actrt2 Actrt2 Vav2 Vav2 Ocln Ocln Cldn13 Cldn13 F11r F11r Mmp2 Mmp2 Noxa1 Noxa1 Mylpf Mylpf Lpxn Lpxn Cldn7 Cldn7 Itgal Itgal Rhoc Rhoc Myl9 Myl9 Pecam1 Pecam1 Jam2 Jam2 Rock1 Rock1 LOC101834491 LOC101834491 Thy1 Thy1 ENSMAUP00000012061 ENSMAUP00000012061 Cldn6 Cldn6 Gnai2 Gnai2 Afdn Afdn Ctnna3 Ctnna3 Prkcb Prkcb ENSMAUP00000013077 ENSMAUP00000013077 ENSMAUP00000013082 ENSMAUP00000013082 Rap1a Rap1a Pxn Pxn Ptpn11 Ptpn11 Sipa1 Sipa1 Itgam Itgam Cldn19 Cldn19 Rhoa Rhoa LOC101835135 LOC101835135 Mapk14 Mapk14 Rhoh Rhoh LOC101831779 LOC101831779 4930544G11Rik 4930544G11Rik Cldn14 Cldn14 Cdh5 Cdh5 Actrt1 Actrt1 Rac2 Rac2 Txk Txk Pik3r2 Pik3r2 Itga4 Itga4 LOC101844635 LOC101844635 Mapk13 Mapk13 Cxcr4 Cxcr4 Cldn8 Cldn8 Cldn17 Cldn17 Rac1 Rac1 Cldn5 Cldn5 Myl12a Myl12a Rapgef3 Rapgef3 Itk Itk Ptk2b Ptk2b Cxcl12 Cxcl12 Vasp Vasp ENSMAUP00000021721 ENSMAUP00000021721 Cldn11 Cldn11 Gabpa Gabpa Pik3ca Pik3ca Cldn15 Cldn15 Ctnnd1 Ctnnd1 Ncf4 Ncf4 Ncf2 Ncf2 Actl11 Actl11 Rap1b Rap1b Cyba Cyba Ctnna1 Ctnna1 Myl2 Myl2 Pik3r2-2 Pik3r2-2 Vav1 Vav1 Rapgef4 Rapgef4 Cldn18 Cldn18 Itgb2 Itgb2 Mapk12 Mapk12 Cldn24 Cldn24 Bcar1 Bcar1 Mapk11 Mapk11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAUP00000017507annotation not available (338 aa)
Vcam1Vascular cell adhesion protein 1. (736 aa)
Rassf5Ras association domain-containing protein 5 isoform X2. (265 aa)
LOC101825458Alpha-actinin-4. (692 aa)
Cldn2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
LOC101831400Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa)
ENSMAUP00000002714annotation not available (58 aa)
Actg1Actin gamma 1. (133 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1293 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
Actn4Actinin alpha 4. (523 aa)
Ctnnb1Catenin beta-1. (781 aa)
Ctnna2Catenin alpha-2 isoform X1. (965 aa)
Itgb1Integrin beta; Belongs to the integrin beta chain family. (92 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Jam3Junctional adhesion molecule C. (310 aa)
Arhgap35Rho GTPase-activating protein 35. (1499 aa)
Actl9Actin-like protein 9; Belongs to the actin family. (415 aa)
Ptk2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (667 aa)
Cdc42Cell division control protein 42 homolog isoform X1. (191 aa)
Actl7aActin-like protein 7A; Belongs to the actin family. (440 aa)
Cd99l2CD99 antigen-like protein 2 isoform X2. (238 aa)
VclVinculin isoform X1. (1129 aa)
Mmp9Matrix metalloproteinase-9. (718 aa)
Actl7bActin-like protein 7B; Belongs to the actin family. (417 aa)
Icam1Intercellular adhesion molecule 1 isoform X2. (516 aa)
EsamEndothelial cell-selective adhesion molecule. (391 aa)
MsnMoesin. (579 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
EzrEzrin. (576 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
Arhgap5Rho GTPase-activating protein 5. (1503 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Cldn4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
Vav3Guanine nucleotide exchange factor VAV3 isoform X1. (847 aa)
Cldn3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
ActbActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Cldn23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (294 aa)
Cldn10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (229 aa)
Cldn20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (208 aa)
Cldn9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
Cldn22Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
Cldn16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (214 aa)
Actrt2Actin-related protein T2; Belongs to the actin family. (377 aa)
Vav2Guanine nucleotide exchange factor VAV2 isoform X2. (868 aa)
OclnOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (107 aa)
Cldn13Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
F11rJunctional adhesion molecule A. (299 aa)
Mmp272 kDa type IV collagenase. (662 aa)
Noxa1NADPH oxidase activator 1 isoform X2. (434 aa)
MylpfMyosin regulatory light chain 2, skeletal muscle isoform. (169 aa)
LpxnLeupaxin; Belongs to the paxillin family. (381 aa)
Cldn7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
ItgalIntegrin alpha-L; Belongs to the integrin alpha chain family. (1159 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Myl9Myosin regulatory light polypeptide 9. (172 aa)
Pecam1Platelet and endothelial cell adhesion molecule 1. (532 aa)
Jam2Junctional adhesion molecule B isoform X2. (303 aa)
Rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
LOC101834491Cytochrome b-245 heavy chain. (93 aa)
Thy1Thy-1 membrane glycoprotein. (162 aa)
ENSMAUP00000012061annotation not available (121 aa)
Cldn6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
AfdnAfadin. (1711 aa)
Ctnna3Catenin alpha-3. (799 aa)
PrkcbProtein kinase C beta. (554 aa)
ENSMAUP00000013077annotation not available (450 aa)
ENSMAUP00000013082annotation not available (176 aa)
Rap1aRas-related protein Rap-1A. (184 aa)
PxnPaxillin; Belongs to the paxillin family. (589 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
Sipa1Signal-induced proliferation-associated protein 1. (1040 aa)
ItgamIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1152 aa)
Cldn19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
RhoaTransforming protein RhoA-like isoform X2. (141 aa)
LOC101835135Actin-like protein 9; Belongs to the actin family. (411 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
RhohRho-related GTP-binding protein RhoH. (191 aa)
LOC101831779Claudin-34-like. (212 aa)
4930544G11RikTransforming protein RhoA-like isoform X1. (193 aa)
Cldn14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa)
Cdh5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
Actrt1Actin-related protein T1; Belongs to the actin family. (376 aa)
Rac2Ras-related C3 botulinum toxin substrate 2. (192 aa)
TxkTyrosine-protein kinase. (417 aa)
Pik3r2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa)
Itga4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1030 aa)
LOC101844635Afadin-like. (157 aa)
Mapk13Mitogen-activated protein kinase. (366 aa)
Cxcr4C-X-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
Cldn8Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
Cldn17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
Rac1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
Cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
Myl12aMyosin regulatory light chain 12B. (172 aa)
Rapgef3Rap guanine nucleotide exchange factor 3 isoform X4. (926 aa)
ItkTyrosine-protein kinase. (619 aa)
Ptk2bProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
Cxcl12Stromal cell-derived factor 1 isoform X1. (119 aa)
VaspVasodilator-stimulated phosphoprotein isoform X4; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (320 aa)
ENSMAUP00000021721annotation not available (153 aa)
Cldn11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (196 aa)
GabpaGA-binding protein alpha chain. (454 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Cldn15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa)
Ctnnd1Catenin delta-1 isoform X7. (967 aa)
Ncf4Neutrophil cytosol factor 4. (260 aa)
Ncf2Neutrophil cytosol factor 2. (526 aa)
Actl11Uncharacterized protein LOC101835075; Belongs to the actin family. (1219 aa)
Rap1bRas-related protein Rap-1b. (184 aa)
CybaCytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (192 aa)
Ctnna1Catenin alpha-1. (905 aa)
Myl2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
Pik3r2-2Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
Vav1Proto-oncogene vav. (845 aa)
Rapgef4Rap guanine nucleotide exchange factor 4 isoform X1. (962 aa)
Cldn18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
Itgb2Integrin beta. (304 aa)
Mapk12Mitogen-activated protein kinase. (367 aa)
Cldn24Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
Bcar1Breast cancer anti-estrogen resistance protein 1 isoform X3. (874 aa)
Mapk11Mitogen-activated protein kinase. (355 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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