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Gucy1a3 Gucy1a3 Arsi Arsi Gucy1b1 Gucy1b1 Gng8 Gng8 Gnao1 Gnao1 Gnai1 Gnai1 Adcy4 Adcy4 Per3 Per3 Gng14 Gng14 Prkcg Prkcg Gngt1 Gngt1 ENSMAUP00000002714 ENSMAUP00000002714 Prkacb Prkacb Kcnj9 Kcnj9 Calml3 Calml3 Prkaca Prkaca Camk2g Camk2g Adcy7 Adcy7 LOC101840621 LOC101840621 Plcb2 Plcb2 ENSMAUP00000006097 ENSMAUP00000006097 Gnai3 Gnai3 Gnb5 Gnb5 Prkca Prkca Cacna1i Cacna1i Adcyap1r1 Adcyap1r1 Gria3 Gria3 Grin2a Grin2a Gnb3 Gnb3 Prkg1 Prkg1 Gng7 Gng7 Gng13 Gng13 Grin2b Grin2b Gnb2 Gnb2 Gng4 Gng4 Adcy6 Adcy6 Adcy5 Adcy5 Kcnj6 Kcnj6 Kcnj5 Kcnj5 Calm3 Calm3 Gnb4 Gnb4 ENSMAUP00000010883 ENSMAUP00000010883 Gucy1a2 Gucy1a2 Adcy1 Adcy1 Mapk3 Mapk3 Per2 Per2 ENSMAUP00000012091 ENSMAUP00000012091 Gng3 Gng3 Gnai2 Gnai2 Plcb4 Plcb4 LOC101837420 LOC101837420 Prkcb Prkcb Nos1ap Nos1ap Camk2d Camk2d LOC101834284 LOC101834284 Adcy2 Adcy2 Rps6ka5 Rps6ka5 Adcy8 Adcy8 Calml4 Calml4 Plcb1 Plcb1 Grin2d Grin2d Cacna1g Cacna1g Gng12 Gng12 Gria2 Gria2 Adcy9 Adcy9 Mtnr1a Mtnr1a Ryr1 Ryr1 Gng10 Gng10 Gria4 Gria4 Nos1 Nos1 Itpr1 Itpr1 Mapk1 Mapk1 Cacna1h Cacna1h Cacna1c Cacna1c Kcnj3 Kcnj3 Creb1 Creb1 Gm4356 Gm4356 Fbxo21 Fbxo21 Prkg2 Prkg2 Gnas Gnas Gngt2 Gngt2 Ptrhd1 Ptrhd1 Adcy3 Adcy3 Calm2 Calm2 Fos Fos Grin2c Grin2c ENSMAUP00000021947 ENSMAUP00000021947 Camk2b Camk2b Grin1 Grin1 Camk2a Camk2a Itpr3 Itpr3 Cacna1d Cacna1d Adcy10 Adcy10 Rasd1 Rasd1 Gng11 Gng11 Gng2 Gng2 Gucy1b2 Gucy1b2 Ryr3 Ryr3 Ryr2 Ryr2 LOC110341725 LOC110341725 Adcyap1 Adcyap1 Calm1 Calm1 Gria1 Gria1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gucy1a3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (128 aa)
ArsiArylsulfatase I. (573 aa)
Gucy1b1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
Gng8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
Gnao1Guanine nucleotide-binding protein G(O) subunit alpha isoform X2. (354 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
Per3LOW QUALITY PROTEIN: period circadian protein homolog 3. (515 aa)
Gng14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
Gngt1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSMAUP00000002714annotation not available (58 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
Kcnj9G protein-activated inward rectifier potassium channel 3 isoform X1. (393 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3. (559 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
LOC101840621G protein-activated inward rectifier potassium channel 1. (234 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ENSMAUP00000006097annotation not available (76 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Gnb5Guanine nucleotide-binding protein subunit beta-5. (388 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Cacna1iVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2197 aa)
Adcyap1r1Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (471 aa)
Gria3Glutamate receptor 3 isoform X2. (895 aa)
Grin2aGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
Gnb3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
Prkg1cGMP-dependent protein kinase 1. (437 aa)
Gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Gng13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
Grin2bGlutamate receptor ionotropic, NMDA 2B. (1483 aa)
Gnb2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (382 aa)
Gng4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Adcy5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
Kcnj6G protein-activated inward rectifier potassium channel 2; This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G- protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due t [...] (386 aa)
Kcnj5G protein-activated inward rectifier potassium channel 4. (343 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
Gnb4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
ENSMAUP00000010883annotation not available (214 aa)
Gucy1a2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (731 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1118 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Per2Period circadian protein homolog 2. (785 aa)
ENSMAUP00000012091annotation not available (86 aa)
Gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
LOC101837420Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein. (270 aa)
PrkcbProtein kinase C beta. (554 aa)
Nos1apCarboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein. (473 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
Rps6ka5Ribosomal protein S6 kinase. (849 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Grin2dGlutamate receptor ionotropic, NMDA 2D. (1251 aa)
Cacna1gVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (385 aa)
Gng12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (50 aa)
Gria2Glutamate receptor 2 isoform X3. (883 aa)
Adcy9Adenylate cyclase type 9 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
Mtnr1aMelatonin receptor type 1A; Belongs to the G-protein coupled receptor 1 family. (322 aa)
Ryr1LOW QUALITY PROTEIN: ryanodine receptor 1. (4094 aa)
Gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
Gria4Glutamate receptor 4 isoform X2. (433 aa)
Nos1Nitric oxide synthase; Produces nitric oxide (NO). (80 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
Cacna1hVoltage-dependent T-type calcium channel subunit alpha-1H isoform X3. (147 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
Kcnj3LOW QUALITY PROTEIN: G protein-activated inward rectifier potassium channel 1. (194 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Gm4356Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
Fbxo21F-box only protein 21 isoform X1. (627 aa)
Prkg2cGMP-dependent protein kinase. (713 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
Gngt2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Ptrhd1LOW QUALITY PROTEIN: putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
Calm2Calmodulin 2. (149 aa)
FosProto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa)
Grin2cGlutamate receptor ionotropic, NMDA 2C isoform X1. (1237 aa)
ENSMAUP00000021947annotation not available (57 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X4. (666 aa)
Grin1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha-1D; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines; B [...] (1378 aa)
Adcy10Adenylate cyclase type 10. (1601 aa)
Rasd1Dexamethasone-induced Ras-related protein 1. (280 aa)
Gng11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
Gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
Gucy1b2Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (757 aa)
Ryr3Ryanodine receptor 3. (4846 aa)
Ryr2LOW QUALITY PROTEIN: ryanodine receptor 2. (4881 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide isoform X1. (175 aa)
Calm1Calmodulin 1. (149 aa)
Gria1Glutamate receptor 1 isoform X2. (907 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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