STRINGSTRING
Camk2d Camk2d Map3k1 Map3k1 Ntrk1 Ntrk1 Jun Jun Pik3cb Pik3cb Mapk8 Mapk8 Nfkbia Nfkbia Traf6 Traf6 Mapkapk2 Mapkapk2 Camk2g Camk2g Calml3 Calml3 Cdc42 Cdc42 Psen1 Psen1 Eras Eras Map2k7 Map2k7 Irak1 Irak1 LOC101831400 LOC101831400 Ngf Ngf Dhdh Dhdh Rps6ka2 Rps6ka2 Ntrk3 Ntrk3 Rps6ka6 Rps6ka6 Pik3cd Pik3cd Plcg1 Plcg1 Zfr Zfr ENSMAUP00000001261 ENSMAUP00000001261 Sos1 Sos1 Arsi Arsi Mapk11 Mapk11 Tp53 Tp53 Calm1 Calm1 Sh2b3 Sh2b3 Mapk12 Mapk12 Ntf3 Ntf3 ENSMAUP00000025330 ENSMAUP00000025330 Map3k3 Map3k3 Csk Csk Prkcd Prkcd Bdnf Bdnf Pik3r2-2 Pik3r2-2 Shc4 Shc4 Camk4 Camk4 Crk Crk Akt2 Akt2 Rap1b Rap1b Hras Hras Nras Nras Shc1 Shc1 Pik3ca Pik3ca Camk2a Camk2a Camk2b Camk2b Ngfr Ngfr Matk Matk Calm2 Calm2 Sort1 Sort1 Irak3 Irak3 Map3k5 Map3k5 Nfkb1 Nfkb1 Rps6ka1 Rps6ka1 Frs2 Frs2 Rac1 Rac1 Kras Kras Mapk9 Mapk9 Mapk13 Mapk13 Bex3 Bex3 Mapk1 Mapk1 Mapk10 Mapk10 Grb2 Grb2 Pik3r2 Pik3r2 Crkl Crkl Zfr2 Zfr2 4930544G11Rik 4930544G11Rik Akt3 Akt3 Braf Braf Mapk14 Mapk14 Irak4 Irak4 Gsk3b Gsk3b Arhgdib Arhgdib Raf1 Raf1 Rela Rela Rps6ka3 Rps6ka3 Map2k5 Map2k5 Bax Bax Rhoa Rhoa Ikbkb Ikbkb Calml4 Calml4 Irs1 Irs1 Ntrk2 Ntrk2 Nfkbib Nfkbib ENSMAUP00000015128 ENSMAUP00000015128 Psen2 Psen2 Sh2b2 Sh2b2 Rps6ka5 Rps6ka5 Csde1 Csde1 Foxo3 Foxo3 Cep152 Cep152 Ptpn11 Ptpn11 Bad Bad Rap1a Rap1a Sos2 Sos2 Akt1 Akt1 Mapk7 Mapk7 Rapgef1 Rapgef1 Mapk3 Mapk3 Atf4 Atf4 Nfkbie Nfkbie Maged1 Maged1 Map2k2 Map2k2 ENSMAUP00000010883 ENSMAUP00000010883 Kidins220 Kidins220 Calm3 Calm3 Rhoc Rhoc Sh2b1 Sh2b1 Map2k1 Map2k1 Bcl2 Bcl2 Prdm4 Prdm4 Tp73 Tp73 Shc3 Shc3 Ywhae Ywhae Gab1 Gab1 Znf274 Znf274 Ripk2 Ripk2 Ntf4 Ntf4 Arhgdig Arhgdig Arhgdia Arhgdia Pik3r1 Pik3r1 Pdpk1 Pdpk1 ENSMAUP00000006097 ENSMAUP00000006097 Faslg Faslg Shc2 Shc2 Plcg2 Plcg2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
Map3k1Mitogen-activated protein kinase kinase kinase 1. (1475 aa)
Ntrk1Tyrosine-protein kinase receptor. (799 aa)
JunTranscription factor AP-1; Belongs to the bZIP family. (338 aa)
Pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa)
Mapk8Mitogen-activated protein kinase. (427 aa)
NfkbiaNF-kappa-B inhibitor alpha. (314 aa)
Traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
Mapkapk2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (386 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3. (559 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Cdc42Cell division control protein 42 homolog isoform X1. (191 aa)
Psen1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
ErasGTPase ERas. (228 aa)
Map2k7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (520 aa)
Irak1Interleukin-1 receptor-associated kinase 1 isoform X2. (747 aa)
LOC101831400Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa)
NgfBeta-nerve growth factor; Belongs to the NGF-beta family. (112 aa)
DhdhTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (297 aa)
Rps6ka2Ribosomal protein S6 kinase. (733 aa)
Ntrk3Tyrosine-protein kinase receptor. (864 aa)
Rps6ka6Ribosomal protein S6 kinase. (861 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
Plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1293 aa)
ZfrZinc finger RNA-binding protein isoform X2. (1077 aa)
ENSMAUP00000001261annotation not available (61 aa)
Sos1Son of sevenless homolog 1. (1319 aa)
ArsiArylsulfatase I. (573 aa)
Mapk11Mitogen-activated protein kinase. (355 aa)
Tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (395 aa)
Calm1Calmodulin 1. (149 aa)
Sh2b3SH2B adapter protein 3 isoform X1. (551 aa)
Mapk12Mitogen-activated protein kinase. (367 aa)
Ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (271 aa)
ENSMAUP00000025330annotation not available (154 aa)
Map3k3Mitogen-activated protein kinase kinase kinase 3. (550 aa)
CskTyrosine-protein kinase. (450 aa)
PrkcdProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
BdnfBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (287 aa)
Pik3r2-2Phosphoinositide-3-kinase regulatory subunit 2. (71 aa)
Shc4SHC adaptor protein 4. (204 aa)
Camk4Calcium/calmodulin-dependent protein kinase type IV isoform X1; Belongs to the protein kinase superfamily. (466 aa)
CrkAdapter molecule crk isoform X1. (304 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Rap1bRas-related protein Rap-1b. (184 aa)
HrasGTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
NrasNRAS proto-oncogene, GTPase. (98 aa)
Shc1SHC-transforming protein 1 isoform X1. (579 aa)
Pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X4. (666 aa)
NgfrTumor necrosis factor receptor superfamily member 16. (431 aa)
MatkTyrosine-protein kinase. (466 aa)
Calm2Calmodulin 2. (149 aa)
Sort1Sortilin. (835 aa)
Irak3Interleukin-1 receptor-associated kinase 3. (382 aa)
Map3k5Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1381 aa)
Nfkb1Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa)
Rps6ka1Ribosomal protein S6 kinase. (743 aa)
Frs2Fibroblast growth factor receptor substrate 2. (510 aa)
Rac1Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa)
KrasGTPase KRas isoform X3. (189 aa)
Mapk9Mitogen-activated protein kinase. (423 aa)
Mapk13Mitogen-activated protein kinase. (366 aa)
Bex3Protein BEX3 isoform X1. (120 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
Mapk10Mitogen-activated protein kinase 10. (252 aa)
Grb2Growth factor receptor-bound protein 2. (217 aa)
Pik3r2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa)
CrklCrk-like protein. (303 aa)
Zfr2Zinc finger RNA binding protein 2. (730 aa)
4930544G11RikTransforming protein RhoA-like isoform X1. (193 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
BrafSerine/threonine-protein kinase B-raf. (710 aa)
Mapk14Mitogen-activated protein kinase. (360 aa)
Irak4Interleukin-1 receptor-associated kinase 4. (461 aa)
Gsk3bGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (429 aa)
ArhgdibRho GDP-dissociation inhibitor 2. (134 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
RelaTranscription factor p65 isoform X1. (260 aa)
Rps6ka3Ribosomal protein S6 kinase. (740 aa)
Map2k5Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily. (448 aa)
BaxApoptosis regulator BAX isoform X1. (192 aa)
RhoaTransforming protein RhoA-like isoform X2. (141 aa)
IkbkbInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
Irs1Insulin receptor substrate 1. (1233 aa)
Ntrk2Tyrosine-protein kinase receptor. (823 aa)
NfkbibNF-kappa-B inhibitor beta. (358 aa)
ENSMAUP00000015128annotation not available (114 aa)
Psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
Sh2b2SH2B adapter protein 2 isoform X1. (616 aa)
Rps6ka5Ribosomal protein S6 kinase. (849 aa)
Csde1Cold shock domain-containing protein E1 isoform X3. (798 aa)
Foxo3Forkhead box protein O3. (672 aa)
Cep152Centrosomal protein of 152 kDa. (1691 aa)
Ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
BadBcl2-associated agonist of cell death isoform X1. (204 aa)
Rap1aRas-related protein Rap-1A. (184 aa)
Sos2Son of sevenless homolog 2 isoform X1. (1308 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (806 aa)
Rapgef1Rap guanine nucleotide exchange factor 1. (1202 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
NfkbieNF-kappa-B inhibitor epsilon. (362 aa)
Maged1Melanoma-associated antigen D1 isoform X1. (776 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
ENSMAUP00000010883annotation not available (214 aa)
Kidins220Kinase D-interacting substrate of 220 kDa. (1661 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
RhocRho-related GTP-binding protein RhoC. (193 aa)
Sh2b1SH2B adapter protein 1. (757 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
Bcl2Apoptosis regulator Bcl-2. (236 aa)
Prdm4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (802 aa)
Tp73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (286 aa)
Shc3SHC-transforming protein 3. (595 aa)
Ywhae14-3-3 protein epsilon isoform X1; Belongs to the 14-3-3 family. (255 aa)
Gab1GRB2-associated-binding protein 1; Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway. (665 aa)
Znf274Neurotrophin receptor-interacting factor homolog isoform X1. (848 aa)
Ripk2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (325 aa)
Ntf4Neurotrophin-4; Belongs to the NGF-beta family. (209 aa)
ArhgdigRho GDP-dissociation inhibitor 3 isoform X1. (225 aa)
ArhgdiaRho GDP-dissociation inhibitor 1. (204 aa)
Pik3r1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Pdpk13-phosphoinositide-dependent protein kinase 1 isoform X2. (559 aa)
ENSMAUP00000006097annotation not available (76 aa)
FaslgTumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa)
Shc2SHC-transforming protein 2. (573 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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