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Camk2b Camk2b Arsi Arsi Kcnn3 Kcnn3 Adcy4 Adcy4 Prkcg Prkcg ENSMAUP00000002714 ENSMAUP00000002714 Prkacb Prkacb Creb3l1 Creb3l1 Gck Gck Gna11 Gna11 Cacna1s Cacna1s Prkaca Prkaca Slc2a2 Slc2a2 Kcnmb3 Kcnmb3 Camk2g Camk2g Rab3a Rab3a Adcy7 Adcy7 Kcnmb2 Kcnmb2 Plcb2 Plcb2 Kcnj11 Kcnj11 Chrm3 Chrm3 Abcc8 Abcc8 LOC101826865 LOC101826865 Ffar1 Ffar1 Kcnn4 Kcnn4 Creb3l2 Creb3l2 Creb5 Creb5 Prkca Prkca Vamp2 Vamp2 Adcyap1r1 Adcyap1r1 Gip Gip Kcnn1 Kcnn1 Atp1a2 Atp1a2 Gnaq Gnaq Fap Fap Adcy6 Adcy6 Adcy5 Adcy5 ENSMAUP00000010883 ENSMAUP00000010883 Adcy1 Adcy1 Atf4 Atf4 Rab3c Rab3c Rab3b Rab3b Plcb4 Plcb4 Rims2 Rims2 Creb3 Creb3 Prkcb Prkcb Kcnmb1 Kcnmb1 Atp1a4 Atp1a4 Camk2d Camk2d Kcnn2 Kcnn2 LOC101834284 LOC101834284 Glp1r Glp1r Adcy2 Adcy2 Adcy8 Adcy8 Per1 Per1 Atf6b Atf6b Kcnma1 Kcnma1 Plcb1 Plcb1 Adcy9 Adcy9 Atp1b4 Atp1b4 Cck Cck Gpr119 Gpr119 Atp1a1 Atp1a1 Atp1b1 Atp1b1 Slc2a1 Slc2a1 Kcnu1 Kcnu1 Cacna1c Cacna1c Fxyd2 Fxyd2 Creb1 Creb1 Ins Ins Atf2 Atf2 Trpm4 Trpm4 Gnas Gnas Ptrhd1 Ptrhd1 Adcy3 Adcy3 Camk2a Camk2a Itpr3 Itpr3 Cacna1d Cacna1d Cckar Cckar Tnik Tnik Creb3l3 Creb3l3 Pdx1 Pdx1 Rapgef4 Rapgef4 Kcnmb4 Kcnmb4 Cacna1f Cacna1f Ryr2 Ryr2 LOC110341725 LOC110341725 Atp1b2 Atp1b2 Snap25 Snap25 Adcyap1 Adcyap1 Stx1a Stx1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X4. (666 aa)
ArsiArylsulfatase I. (573 aa)
Kcnn3Small conductance calcium-activated potassium channel protein 3. (728 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
ENSMAUP00000002714annotation not available (58 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
GckPhosphotransferase. (430 aa)
Gna11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Slc2a2Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
Kcnmb3Calcium-activated potassium channel subunit beta-3. (182 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3. (559 aa)
Rab3aRas-related protein Rab-3A. (220 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
Kcnmb2Calcium-activated potassium channel subunit beta-2. (235 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
Kcnj11ATP-sensitive inward rectifier potassium channel 11 isoform X1. (390 aa)
Chrm3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (589 aa)
Abcc8ATP-binding cassette sub-family C member 8 isoform X2. (1582 aa)
LOC101826865Cyclic AMP-responsive element-binding protein 3-like protein 4. (213 aa)
Ffar1Free fatty acid receptor 1; G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation. Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular c [...] (300 aa)
Kcnn4Intermediate conductance calcium-activated potassium channel protein 4. (426 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X2. (520 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X3. (508 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Vamp2Vesicle-associated membrane protein 2. (115 aa)
Adcyap1r1Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (471 aa)
GipGastric inhibitory polypeptide. (141 aa)
Kcnn1Small conductance calcium-activated potassium channel protein 1 isoform X2. (533 aa)
Atp1a2Sodium/potassium-transporting ATPase subunit alpha. (918 aa)
GnaqGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
FapProlyl endopeptidase FAP; Belongs to the peptidase S9B family. (663 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Adcy5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
ENSMAUP00000010883annotation not available (214 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1118 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
Rab3cRas-related protein Rab-3C isoform X1. (228 aa)
Rab3bRas-related protein Rab-3B; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (219 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
Rims2Regulating synaptic membrane exocytosis protein 2. (1453 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (386 aa)
PrkcbProtein kinase C beta. (554 aa)
Kcnmb1Calcium-activated potassium channel subunit beta-1. (191 aa)
Atp1a4Sodium/potassium-transporting ATPase subunit alpha. (937 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
Kcnn2Small conductance calcium-activated potassium channel protein 2 isoform X1. (839 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
Glp1rGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (449 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
Per1Period circadian protein homolog 1 isoform X1. (1304 aa)
Atf6bCyclic AMP-dependent transcription factor ATF-6 beta isoform X2. (73 aa)
Kcnma1Calcium-activated potassium channel subunit alpha-1 isoform X16. (1238 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Adcy9Adenylate cyclase type 9 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
Atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (355 aa)
CckCholecystokinin precursor. (115 aa)
Gpr119Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (334 aa)
Atp1a1Sodium/potassium-transporting ATPase subunit alpha. (1019 aa)
Atp1b1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
Slc2a1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
Kcnu1Potassium channel subfamily U member 1. (1092 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
Fxyd2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (64 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
InsInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa)
Trpm4Transient receptor potential cation channel subfamily M member 4 isoform X1. (1367 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
Ptrhd1LOW QUALITY PROTEIN: putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha-1D; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines; B [...] (1378 aa)
CckarCholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (429 aa)
TnikTRAF2 and NCK-interacting protein kinase. (538 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (475 aa)
Pdx1Pancreas/duodenum homeobox protein 1; Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element [...] (283 aa)
Rapgef4Rap guanine nucleotide exchange factor 4 isoform X1. (962 aa)
Kcnmb4Calcium-activated potassium channel subunit beta-4. (210 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1979 aa)
Ryr2LOW QUALITY PROTEIN: ryanodine receptor 2. (4881 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
Atp1b2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
Snap25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide isoform X1. (175 aa)
Stx1asyntaxin-1A isoform X1; Belongs to the syntaxin family. (288 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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