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Creb3l3 Creb3l3 Wnt3a Wnt3a Wnt5b Wnt5b Wnt9a Wnt9a Asip Asip LOC110341725 LOC110341725 Fzd2 Fzd2 Efcab3 Efcab3 Fzd5 Fzd5 Calm1 Calm1 LOC106021121 LOC106021121 Fzd6 Fzd6 Arsi Arsi Fzd4 Fzd4 Gnao1 Gnao1 Fzd1 Fzd1 Dvl2 Dvl2 Gnai1 Gnai1 Adcy4 Adcy4 Ctnnb1 Ctnnb1 Tyr Tyr Prkcg Prkcg Wnt6 Wnt6 ENSMAUP00000002428 ENSMAUP00000002428 Wnt10a Wnt10a ENSMAUP00000002714 ENSMAUP00000002714 Prkacb Prkacb Creb3l1 Creb3l1 Eras Eras Ep300 Ep300 Mitf Mitf Calml3 Calml3 Prkaca Prkaca Rem1 Rem1 Camk2g Camk2g Adcy7 Adcy7 Wnt2b Wnt2b Lef1 Lef1 Plcb2 Plcb2 Gem Gem Rrad Rrad LOC101826865 LOC101826865 Dct Dct Pomc Pomc Fzd10 Fzd10 ENSMAUP00000006097 ENSMAUP00000006097 Gnai3 Gnai3 Wnt11 Wnt11 Creb3l2 Creb3l2 Prkca Prkca Fzd9 Fzd9 Mc1r Mc1r Wnt7b Wnt7b Wnt8a Wnt8a Fzd7 Fzd7 Crebbp Crebbp ENSMAUP00000009932 ENSMAUP00000009932 Wnt4 Wnt4 Adcy6 Adcy6 Map2k1 Map2k1 Adcy5 Adcy5 Calm3 Calm3 ENSMAUP00000010883 ENSMAUP00000010883 Map2k2 Map2k2 Adcy1 Adcy1 Wnt10b Wnt10b Mapk3 Mapk3 Wnt1 Wnt1 Tcf7 Tcf7 Wnt2 Wnt2 Gnai2 Gnai2 Plcb4 Plcb4 Creb3 Creb3 Prkcb Prkcb Kit Kit Camk2d Camk2d LOC101834284 LOC101834284 Csde1 Csde1 Adcy2 Adcy2 Adcy8 Adcy8 Tcf7l2 Tcf7l2 Wnt5a Wnt5a Ednrb Ednrb Fzd8 Fzd8 Calml4 Calml4 Wnt16 Wnt16 Plcb1 Plcb1 Raf1 Raf1 Tcf7l1 Tcf7l1 Gsk3b Gsk3b Adcy9 Adcy9 Edn1 Edn1 Kitl Kitl Wnt7a Wnt7a Mapk1 Mapk1 Kras Kras Wnt9b Wnt9b Wnt8b Wnt8b Tyrp1 Tyrp1 Creb1 Creb1 Wnt3 Wnt3 Gnas Gnas Dvl3 Dvl3 Ptrhd1 Ptrhd1 Adcy3 Adcy3 Calm2 Calm2 Camk2b Camk2b Camk2a Camk2a Nras Nras Hras Hras Dvl1 Dvl1 Fzd3 Fzd3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (475 aa)
Wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
Wnt9aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (191 aa)
AsipAgouti-signaling protein. (131 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
Fzd2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
Efcab3EF-hand calcium-binding domain-containing protein 3. (430 aa)
Fzd5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
Calm1Calmodulin 1. (149 aa)
LOC106021121Uncharacterized protein LOC106021121. (209 aa)
Fzd6Frizzled-6; Belongs to the G-protein coupled receptor Fz/Smo family. (684 aa)
ArsiArylsulfatase I. (573 aa)
Fzd4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (535 aa)
Gnao1Guanine nucleotide-binding protein G(O) subunit alpha isoform X2. (354 aa)
Fzd1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa)
Dvl2Segment polarity protein dishevelled homolog DVL-2. (299 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Adcy4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
Ctnnb1Catenin beta-1. (781 aa)
TyrTyrosinase. (530 aa)
PrkcgProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (612 aa)
Wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ENSMAUP00000002428annotation not available (67 aa)
Wnt10aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (418 aa)
ENSMAUP00000002714annotation not available (58 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
ErasGTPase ERas. (228 aa)
Ep300Histone acetyltransferase p300 isoform X3. (2417 aa)
MitfMicrophthalmia-associated transcription factor isoform X1. (526 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Rem1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (297 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3. (559 aa)
Adcy7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa)
Wnt2bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
Lef1Lymphoid enhancer-binding factor 1 isoform X2. (397 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
GemGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
RradGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (307 aa)
LOC101826865Cyclic AMP-responsive element-binding protein 3-like protein 4. (213 aa)
DctL-dopachrome tautomerase. (520 aa)
PomcPro-opiomelanocortin. (234 aa)
Fzd10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
ENSMAUP00000006097annotation not available (76 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X2. (520 aa)
PrkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
Fzd9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (592 aa)
Mc1rMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (317 aa)
Wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
Wnt8aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
Fzd7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (572 aa)
CrebbpCREB-binding protein. (2433 aa)
ENSMAUP00000009932annotation not available (203 aa)
Wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Map2k1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
Adcy5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
ENSMAUP00000010883annotation not available (214 aa)
Map2k2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
Adcy1Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1118 aa)
Wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
Mapk3Mitogen-activated protein kinase. (380 aa)
Wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
Tcf7Transcription factor 7 isoform X3. (303 aa)
Wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (321 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (386 aa)
PrkcbProtein kinase C beta. (554 aa)
KitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
Csde1Cold shock domain-containing protein E1 isoform X3. (798 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
Adcy8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1248 aa)
Tcf7l2Transcription factor 7-like 2 isoform X17. (598 aa)
Wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
EdnrbEndothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (432 aa)
Fzd8LOW QUALITY PROTEIN: frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (675 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
Wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Raf1RAF proto-oncogene serine/threonine-protein kinase. (648 aa)
Tcf7l1Transcription factor 7-like 1. (558 aa)
Gsk3bGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (429 aa)
Adcy9Adenylate cyclase type 9 isoform X2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1354 aa)
Edn1Endothelin-1. (202 aa)
KitlKIT ligand. (195 aa)
Wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (318 aa)
Mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (358 aa)
KrasGTPase KRas isoform X3. (189 aa)
Wnt9bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
Wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
Tyrp15,6-dihydroxyindole-2-carboxylic acid oxidase. (537 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
Dvl3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (718 aa)
Ptrhd1LOW QUALITY PROTEIN: putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
Adcy3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
Calm2Calmodulin 2. (149 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X4. (666 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
NrasNRAS proto-oncogene, GTPase. (98 aa)
HrasGTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. (189 aa)
Dvl1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (695 aa)
Fzd3Frizzled-3 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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