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ENSMAUP00000015439 ENSMAUP00000015439 LOC101834284 LOC101834284 Camk2d Camk2d Pck2 Pck2 Akt1 Akt1 Creb3 Creb3 Itpr2 Itpr2 Plcb4 Plcb4 Pygl Pygl Ppp3ca Ppp3ca Atf4 Atf4 Parp8 Parp8 Cpt1b Cpt1b Ppargc1a Ppargc1a Prkag1 Prkag1 Ldhc Ldhc ENSMAUP00000010883 ENSMAUP00000010883 Calm3 Calm3 Fap Fap G6pc3 G6pc3 LOC101825203 LOC101825203 Crebbp Crebbp ENSMAUP00000009156 ENSMAUP00000009156 Ppp4c Ppp4c Prkag2 Prkag2 ENSMAUP00000000168 ENSMAUP00000000168 Arsi Arsi Foxo1 Foxo1 Ppp3cc Ppp3cc Crtc2 Crtc2 ENSMAUP00000001331 ENSMAUP00000001331 Prkaa1 Prkaa1 Phkg1 Phkg1 Ppp4r3a Ppp4r3a Phka2 Phka2 G6pc G6pc Pdha1 Pdha1 Ppp3r2 Ppp3r2 Prkacb Prkacb Creb3l1 Creb3l1 Gck Gck Sik2 Sik2 Ep300 Ep300 Ppp3cb Ppp3cb Calml3 Calml3 Pdhb Pdhb Prkaca Prkaca Slc2a2 Slc2a2 Camk2g Camk2g Ppara Ppara Prmt1 Prmt1 Plcb2 Plcb2 Prkaa2 Prkaa2 LOC101826865 LOC101826865 ENSMAUP00000005871 ENSMAUP00000005871 ENSMAUP00000006097 ENSMAUP00000006097 Sirt1 Sirt1 Ldhb Ldhb Creb3l2 Creb3l2 Creb5 Creb5 Phka1 Phka1 Phkg2 Phkg2 Prkag3 Prkag3 ENSMAUP00000015209 ENSMAUP00000015209 Calm1 Calm1 G6pc2 G6pc2 Nostrin Nostrin ENSMAUP00000025111 ENSMAUP00000025111 LOC110341725 LOC110341725 Pgam1 Pgam1 Pkm Pkm Prkab1 Prkab1 Creb3l3 Creb3l3 Tnik Tnik Akt2 Akt2 ENSMAUP00000023654 ENSMAUP00000023654 Pck1 Pck1 Itpr3 Itpr3 Camk2a Camk2a Camk2b Camk2b Calm2 Calm2 Ppp4r3b Ppp4r3b Acacb Acacb Gnas Gnas Sik1 Sik1 Pfkfb1 Pfkfb1 Atf2 Atf2 Creb1 Creb1 Cpt1a Cpt1a Slc2a1 Slc2a1 Pfkl Pfkl Pygb Pygb Fbp2 Fbp2 Gys2 Gys2 Acaca Acaca Itpr1 Itpr1 Phkb Phkb Pfkm Pfkm Akt3 Akt3 Gys1 Gys1 Fbp1 Fbp1 Gcgr Gcgr Cpt1c Cpt1c ENSMAUP00000016276 ENSMAUP00000016276 LOC101824340 LOC101824340 Plcb1 Plcb1 Pgam1-2 Pgam1-2 Prkab2 Prkab2 Calml4 Calml4 Ppp3r1 Ppp3r1 LOC101830866 LOC101830866 Pygm Pygm ENSMAUP00000014449 ENSMAUP00000014449 Pfkp Pfkp Adcy2 Adcy2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMAUP00000015439annotation not available (155 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
Camk2dCalcium/calmodulin-dependent protein kinase type II subunit delta. (160 aa)
Pck2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (474 aa)
Akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
Creb3Cyclic AMP-responsive element-binding protein 3 isoform X1. (386 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (2584 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
PyglGlycogen phosphorylase L. (728 aa)
Ppp3caSerine/threonine-protein phosphatase. (521 aa)
Atf4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
Parp8Poly [ADP-ribose] polymerase. (890 aa)
Cpt1bCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1. (525 aa)
Ppargc1aPeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (796 aa)
Prkag15'-AMP-activated protein kinase subunit gamma-1 isoform X2. (330 aa)
LdhcL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (300 aa)
ENSMAUP00000010883annotation not available (214 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
FapProlyl endopeptidase FAP; Belongs to the peptidase S9B family. (663 aa)
G6pc3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
LOC101825203Carnitine O-palmitoyltransferase 1, brain isoform. (57 aa)
CrebbpCREB-binding protein. (2433 aa)
ENSMAUP00000009156annotation not available (73 aa)
Ppp4cSerine/threonine-protein phosphatase. (307 aa)
Prkag25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (443 aa)
ENSMAUP00000000168annotation not available (146 aa)
ArsiArylsulfatase I. (573 aa)
Foxo1Forkhead box protein O1. (633 aa)
Ppp3ccSerine/threonine-protein phosphatase. (514 aa)
Crtc2CREB-regulated transcription coactivator 2. (513 aa)
ENSMAUP00000001331annotation not available (451 aa)
Prkaa1Non-specific serine/threonine protein kinase. (522 aa)
Phkg1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (370 aa)
Ppp4r3aSerine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1. (833 aa)
Phka2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1229 aa)
G6pcGlucose-6-phosphatase. (320 aa)
Pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
Ppp3r2Calcineurin subunit B type 2. (183 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
Creb3l1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
GckPhosphotransferase. (430 aa)
Sik2Serine/threonine-protein kinase SIK2. (899 aa)
Ep300Histone acetyltransferase p300 isoform X3. (2417 aa)
Ppp3cbSerine/threonine-protein phosphatase. (483 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
PdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Slc2a2Solute carrier family 2, facilitated glucose transporter member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
Camk2gCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3. (559 aa)
PparaPeroxisome proliferator-activated receptor alpha isoform X2. (468 aa)
Prmt1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
Prkaa2Non-specific serine/threonine protein kinase. (542 aa)
LOC101826865Cyclic AMP-responsive element-binding protein 3-like protein 4. (213 aa)
ENSMAUP00000005871annotation not available (54 aa)
ENSMAUP00000006097annotation not available (76 aa)
Sirt1NAD-dependent protein deacetylase sirtuin-1. (691 aa)
LdhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
Creb3l2Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X2. (520 aa)
Creb5Cyclic AMP-responsive element-binding protein 5 isoform X3. (508 aa)
Phka1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1037 aa)
Phkg2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; Belongs to the protein kinase superfamily. (145 aa)
Prkag35'-AMP-activated protein kinase subunit gamma-3. (481 aa)
ENSMAUP00000015209annotation not available (226 aa)
Calm1Calmodulin 1. (149 aa)
G6pc2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
NostrinNostrin. (309 aa)
ENSMAUP00000025111annotation not available (287 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
Pgam1Phosphoglycerate mutase 1. (168 aa)
PkmPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
Prkab15'-AMP-activated protein kinase subunit beta-1. (270 aa)
Creb3l3Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1. (475 aa)
TnikTRAF2 and NCK-interacting protein kinase. (538 aa)
Akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSMAUP00000023654annotation not available (488 aa)
Pck1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (623 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
Camk2aCalcium/calmodulin-dependent protein kinase type II subunit alpha; Belongs to the protein kinase superfamily. (459 aa)
Camk2bCalcium/calmodulin-dependent protein kinase type II subunit beta isoform X4. (666 aa)
Calm2Calmodulin 2. (149 aa)
Ppp4r3bSerine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1. (820 aa)
Acacbacetyl-CoA carboxylase 2. (1700 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
Sik1Serine/threonine-protein kinase SIK1. (776 aa)
Pfkfb16-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform X1. (438 aa)
Atf2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (480 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Cpt1aCarnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family. (661 aa)
Slc2a1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa)
PfklATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
PygbAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
Fbp2Fructose-1,6-bisphosphatase isozyme 2 isoform X1; Belongs to the FBPase class 1 family. (339 aa)
Gys2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (706 aa)
Acacaacetyl-CoA carboxylase 1 isoform X1. (2361 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
PhkbPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1085 aa)
PfkmATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
Akt3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
Gys1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
Fbp1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (361 aa)
GcgrGlucagon receptor isoform X2; Belongs to the G-protein coupled receptor 2 family. (492 aa)
Cpt1cCarnitine O-palmitoyltransferase 1, brain isoform; Belongs to the carnitine/choline acetyltransferase family. (349 aa)
ENSMAUP00000016276annotation not available (77 aa)
LOC101824340Poly [ADP-ribose] polymerase. (109 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
Pgam1-2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (226 aa)
Prkab25'-AMP-activated protein kinase subunit beta-2 isoform X1. (271 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
Ppp3r1Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (157 aa)
LOC101830866L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (350 aa)
PygmGlycogen phosphorylase, muscle associated. (676 aa)
ENSMAUP00000014449annotation not available (269 aa)
PfkpATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (714 aa)
Adcy2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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