STRINGSTRING
Gucy1b1 Gucy1b1 Ppp3cc Ppp3cc Gnai1 Gnai1 Ppp3r2 Ppp3r2 Prkacb Prkacb Ppp3cb Ppp3cb Calml3 Calml3 Cacna1s Cacna1s Edn2 Edn2 Prkaca Prkaca Plcb2 Plcb2 ENSMAUP00000006097 ENSMAUP00000006097 Gnai3 Gnai3 Adcyap1r1 Adcyap1r1 Nppa Nppa Agtr1 Agtr1 Adcy6 Adcy6 Adcy5 Adcy5 Calm3 Calm3 Npr1 Npr1 Gucy1a2 Gucy1a2 Ppp3ca Ppp3ca Gnai2 Gnai2 Plcb4 Plcb4 Itpr2 Itpr2 Ptger2 Ptger2 Pde1c Pde1c LOC101834284 LOC101834284 LOC101830097 LOC101830097 Ptger4 Ptger4 Ppp3r1 Ppp3r1 Kcnma1 Kcnma1 Calml4 Calml4 Plcb1 Plcb1 Ace Ace Orai1 Orai1 Edn1 Edn1 Ednra Ednra Aqp1 Aqp1 Itpr1 Itpr1 LOC101840244 LOC101840244 Clca3b Clca3b Adrb2 Adrb2 Edn3 Edn3 Cacna1c Cacna1c Creb1 Creb1 Adora1 Adora1 Prkg2 Prkg2 Agt Agt Pde1a Pde1a Gnas Gnas LOC101830628 LOC101830628 Gucy1a3 Gucy1a3 Ace3 Ace3 Pde1b Pde1b Calm2 Calm2 Ren Ren Adrb3 Adrb3 Itpr3 Itpr3 Cacna1d Cacna1d Kcnj2 Kcnj2 Clca1 Clca1 Clca2 Clca2 Gucy1b2 Gucy1b2 Cacna1f Cacna1f Ctsb Ctsb LOC110341725 LOC110341725 Pde3a Pde3a Adcyap1 Adcyap1 Calm1 Calm1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Gucy1b1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
Ppp3ccSerine/threonine-protein phosphatase. (514 aa)
Gnai1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
Ppp3r2Calcineurin subunit B type 2. (183 aa)
PrkacbcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (399 aa)
Ppp3cbSerine/threonine-protein phosphatase. (483 aa)
Calml3Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
Cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
Edn2Endothelin-2. (177 aa)
PrkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
Plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ENSMAUP00000006097annotation not available (76 aa)
Gnai3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
Adcyap1r1Pituitary adenylate cyclase-activating polypeptide type I receptor; Belongs to the G-protein coupled receptor 2 family. (471 aa)
NppaNatriuretic peptides A. (153 aa)
Agtr1Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Adcy6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
Adcy5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
Calm3Calmodulin-2 isoform X1; Belongs to the calmodulin family. (149 aa)
Npr1Guanylate cyclase. (640 aa)
Gucy1a2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (731 aa)
Ppp3caSerine/threonine-protein phosphatase. (521 aa)
Gnai2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
Plcb41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor type 2. (2584 aa)
Ptger2Prostaglandin E2 receptor EP2 subtype isoform X1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
Pde1cPhosphodiesterase. (539 aa)
LOC101834284Neuroendocrine secretory protein 55-like. (250 aa)
LOC101830097Calcium-activated chloride channel regulator 4A. (784 aa)
Ptger4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (488 aa)
Ppp3r1Protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I). (157 aa)
Kcnma1Calcium-activated potassium channel subunit alpha-1 isoform X16. (1238 aa)
Calml4Calmodulin-like protein 4 isoform X2. (141 aa)
Plcb11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
AceAngiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg- binding ability of the sperm (By similarity). (1314 aa)
Orai1Calcium release-activated calcium channel protein 1. (302 aa)
Edn1Endothelin-1. (202 aa)
EdnraEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
Aqp1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
Itpr1Inositol 1,4,5-trisphosphate receptor type 1 isoform X2. (2757 aa)
LOC101840244type-1A angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Clca3bCalcium-activated chloride channel regulator family member 3-like. (699 aa)
Adrb2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa)
Edn3Endothelin-3. (166 aa)
Cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
Creb1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
Adora1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
Prkg2cGMP-dependent protein kinase. (713 aa)
AgtAngiotensinogen; Belongs to the serpin family. (482 aa)
Pde1aPhosphodiesterase. (536 aa)
GnasGuanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2. (394 aa)
LOC101830628Epithelial chloride channel protein-like. (802 aa)
Gucy1a3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (128 aa)
Ace3Angiotensin-converting enzyme. (738 aa)
Pde1bPhosphodiesterase. (535 aa)
Calm2Calmodulin 2. (149 aa)
RenRenin; Belongs to the peptidase A1 family. (403 aa)
Adrb3Beta-3 adrenergic receptor. (404 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor type 3. (2660 aa)
Cacna1dVoltage-dependent L-type calcium channel subunit alpha-1D; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines; B [...] (1378 aa)
Kcnj2Inward rectifier potassium channel 2. (427 aa)
Clca1Calcium-activated chloride channel regulator 1. (913 aa)
Clca2Calcium-activated chloride channel regulator 2. (674 aa)
Gucy1b2Guanylate cyclase soluble subunit beta-2-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (757 aa)
Cacna1fVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1979 aa)
CtsbCathepsin B; Belongs to the peptidase C1 family. (339 aa)
LOC110341725Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas-like. (854 aa)
Pde3aPhosphodiesterase. (1144 aa)
Adcyap1Pituitary adenylate cyclase-activating polypeptide isoform X1. (175 aa)
Calm1Calmodulin 1. (149 aa)
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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