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| | Ndufs7 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Belongs to the complex I 20 kDa subunit family. (217 aa) |
| | Prkab1 | 5'-AMP-activated protein kinase subunit beta-1. (270 aa) |
| | Pik3r2-2 | Phosphoinositide-3-kinase regulatory subunit 2. (71 aa) |
| | Uqcrq | Cytochrome b-c1 complex subunit 8. (82 aa) |
| | Ndufa11 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. (143 aa) |
| | Yjefn3 | yjeF N-terminal domain-containing protein 3. (248 aa) |
| | Ern1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (373 aa) |
| | Ndufs2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (447 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (514 aa) |
| | COX2 | Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa) |
| | COX3 | Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa) |
| | CYTB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa) |
| | ENSMAUP00000000074 | annotation not available (98 aa) |
| | Ndufb2 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (105 aa) |
| | Ndufa1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (71 aa) |
| | Ndufa9 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. (377 aa) |
| | LOC101827130 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (173 aa) |
| | Ndufb7 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (137 aa) |
| | ENSMAUP00000000683 | annotation not available (256 aa) |
| | Eif2ak3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (1095 aa) |
| | ENSMAUP00000000801 | annotation not available (132 aa) |
| | LOC101842058 | Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | Traf2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | Prkaa1 | Non-specific serine/threonine protein kinase. (522 aa) |
| | Itch | E3 ubiquitin-protein ligase. (841 aa) |
| | ENSMAUP00000001870 | annotation not available (99 aa) |
| | Pik3cd | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa) |
| | LOC101843716 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. (493 aa) |
| | Dhdh | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (297 aa) |
| | Cox8b | Cytochrome c oxidase subunit 8B, mitochondrial. (70 aa) |
| | Cox4i2 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial. (127 aa) |
| | LOC101831400 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (430 aa) |
| | Tnfrsf1a | Tumor necrosis factor receptor superfamily member 1A. (468 aa) |
| | Cebpa | CCAAT/enhancer-binding protein alpha. (364 aa) |
| | Tgfb1 | Transforming growth factor beta-1. (286 aa) |
| | Adipor1 | Adiponectin receptor protein 1. (375 aa) |
| | Cdc42 | Cell division control protein 42 homolog isoform X1. (191 aa) |
| | Casp3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (246 aa) |
| | Cox7c | Cytochrome c oxidase subunit 7C, mitochondrial. (63 aa) |
| | ENSMAUP00000004299 | annotation not available (53 aa) |
| | Lepr | Leptin receptor. (1113 aa) |
| | Ppara | Peroxisome proliferator-activated receptor alpha isoform X2. (468 aa) |
| | Mapk8 | Mitogen-activated protein kinase. (427 aa) |
| | Prkaa2 | Non-specific serine/threonine protein kinase. (542 aa) |
| | Pik3cb | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | Jun | Transcription factor AP-1; Belongs to the bZIP family. (338 aa) |
| | LOC106021303 | Cytochrome c, somatic; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa) |
| | CUNH7orf31 | Uncharacterized protein C7orf31 homolog isoform X1. (589 aa) |
| | Ndufb10 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. (176 aa) |
| | Faslg | Tumor necrosis factor ligand superfamily member 6 isoform X1; Belongs to the tumor necrosis factor family. (279 aa) |
| | Cox4i1 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial. (169 aa) |
| | Pik3r1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | Fam71e2 | Protein FAM71E2. (766 aa) |
| | Ndufa5 | NADH:ubiquinone oxidoreductase subunit A5. (77 aa) |
| | Cox7a2 | Cytochrome c oxidase subunit 7A2, mitochondrial. (83 aa) |
| | Ndufs4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform X1. (176 aa) |
| | Cox7b | Cytochrome c oxidase subunit 7B, mitochondrial. (55 aa) |
| | Cox6a2 | Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa) |
| | Nr1h3 | Oxysterols receptor LXR-alpha isoform X1. (296 aa) |
| | Ndufv2 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (250 aa) |
| | Fas | Tumor necrosis factor receptor superfamily member 6 isoform X1. (323 aa) |
| | Prkag3 | 5'-AMP-activated protein kinase subunit gamma-3. (481 aa) |
| | Prkag2 | 5'-AMP-activated protein kinase subunit gamma-2 isoform X1. (443 aa) |
| | Ndufc2 | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa) |
| | Bcl2l11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (197 aa) |
| | Adipor2 | Adiponectin receptor protein 2. (386 aa) |
| | Ndufa12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (149 aa) |
| | Ndufs3 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (263 aa) |
| | Uqcrc1 | Cytochrome b-c1 complex subunit 1, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradie [...] (447 aa) |
| | ENSMAUP00000009257 | annotation not available (614 aa) |
| | Sdhc | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial. (153 aa) |
| | Mlx | Max-like protein X isoform X1. (298 aa) |
| | Casp7 | Caspase-7 subunit p11; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP- ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death (By similarity). (297 aa) |
| | Socs3 | Suppressor of cytokine signaling 3. (225 aa) |
| | Il6r | Interleukin-6 receptor subunit alpha. (460 aa) |
| | Cyc1 | Cytochrome c1, heme protein, mitochondrial. (173 aa) |
| | Cox6b1 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (87 aa) |
| | Mlxip | MLX-interacting protein. (812 aa) |
| | Ndufs6 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (116 aa) |
| | Ndufa7 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (113 aa) |
| | Prkag1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform X2. (330 aa) |
| | Ndufb9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family. (179 aa) |
| | Tnf | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | Gsk3a | Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (461 aa) |
| | Uqcrc2 | Cytochrome b-c1 complex subunit 2, mitochondrial; Belongs to the peptidase M16 family. (453 aa) |
| | Eif2s1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | Irs1 | Insulin receptor substrate 1. (1233 aa) |
| | LOC101833775 | Cytochrome c oxidase subunit 6A, mitochondrial. (86 aa) |
| | Ikbkb | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (757 aa) |
| | Cox8a | Cytochrome c oxidase subunit 8A, mitochondrial. (69 aa) |
| | Prkab2 | 5'-AMP-activated protein kinase subunit beta-2 isoform X1. (271 aa) |
| | Ndufa10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (89 aa) |
| | Bax | Apoptosis regulator BAX isoform X1. (192 aa) |
| | Rela | Transcription factor p65 isoform X1. (260 aa) |
| | Ndufa3 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. (99 aa) |
| | ENSMAUP00000016486 | annotation not available (125 aa) |
| | LOC101828586 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (102 aa) |
| | Gsk3b | Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (429 aa) |
| | Map3k11 | Mitogen-activated protein kinase kinase kinase 11. (265 aa) |
| | Sdhb | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) |
| | Uqcr11 | Cytochrome b-c1 complex subunit 10. (56 aa) |
| | Ndufa2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa) |
| | Srebf1 | Sterol regulatory element-binding protein 1 isoform X1. (1130 aa) |
| | Ndufa8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8. (172 aa) |
| | Akt3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | Cyct | Cytochrome c, testis-specific; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | Uqcrfs1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (273 aa) |
| | Rxra | Retinoic acid receptor RXR-alpha. (457 aa) |
| | Ndufa4l2 | NDUFA4 mitochondrial complex associated like 2. (57 aa) |
| | Pik3r2 | Phosphatidylinositol 3-kinase regulatory subunit beta isoform X2. (488 aa) |
| | Ndufa4 | Cytochrome c oxidase subunit NDUFA4. (82 aa) |
| | Ndufs1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (727 aa) |
| | Mapk10 | Mitogen-activated protein kinase 10. (252 aa) |
| | Uqcrb | Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (112 aa) |
| | Mapk9 | Mitogen-activated protein kinase. (423 aa) |
| | Ndufa5-2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (113 aa) |
| | Ndufc1 | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa) |
| | Ndufs5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (106 aa) |
| | Ndufv1 | NADH:ubiquinone oxidoreductase core subunit V1. (115 aa) |
| | Il1b | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa) |
| | Il6 | Interleukin-6. (212 aa) |
| | Ndufb3 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (106 aa) |
| | Rac1 | Ras-related C3 botulinum toxin substrate 1 isoform X1. (211 aa) |
| | LOC101834557 | Cytochrome c oxidase subunit 5B, mitochondrial. (129 aa) |
| | Cox7a1 | Cytochrome c oxidase subunit 7A1, mitochondrial. (89 aa) |
| | Ndufs8 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1. (210 aa) |
| | Ndufb5 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial. (189 aa) |
| | Nfkb1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (970 aa) |
| | Map3k5 | Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1381 aa) |
| | Cox8c | Cytochrome c oxidase subunit 8C, mitochondrial. (70 aa) |
| | Ins | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | Cox7a2l | Cytochrome c oxidase subunit 7A2 like. (96 aa) |
| | Casp8 | Caspase-8 isoform X1; Belongs to the peptidase C14A family. (481 aa) |
| | Il1a | Interleukin-1; Belongs to the IL-1 family. (269 aa) |
| | Sdhd | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) |
| | ENSMAUP00000021279 | annotation not available (98 aa) |
| | Ndufa13 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (144 aa) |
| | Ndufb6 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6. (128 aa) |
| | Ndufb11 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. (151 aa) |
| | Fos | Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity). In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and [...] (381 aa) |
| | Mlxipl | Carbohydrate-responsive element-binding protein isoform X1. (859 aa) |
| | LOC101841714 | Cytochrome b-c1 complex subunit 6, mitochondrial. (55 aa) |
| | Atf4 | Cyclic AMP-dependent transcription factor ATF-4. (350 aa) |
| | ENSMAUP00000012115 | annotation not available (87 aa) |
| | Cox5a | Cytochrome c oxidase subunit 5A, mitochondrial. (133 aa) |
| | Pklr | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | Akt1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | Xbp1 | X-box-binding protein 1. (210 aa) |
| | LOC110340045 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (136 aa) |
| | Kiaa1958 | Uncharacterized protein KIAA1958 homolog. (716 aa) |
| | Pik3ca | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | Ndufb4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa) |
| | Ndufv3 | NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1. (470 aa) |
| | Ndufb8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa) |
| | Adipoq | Adiponectin isoform X1. (244 aa) |
| | Irs2 | Insulin receptor substrate 2. (1333 aa) |
| | Sdha | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (662 aa) |
| | Akt2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | Lep | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
